Simvastatin Prevents Load-Induced Protein Tyrosine Nitration in Overloaded Hearts

Hypertension

Volumn 43, Issue 5, 2004, Pages 1060-1066

  Nadruz Jr , Wilson ^a   Lagosta, Valquer Jose ^a   Moreno Jr , Heitor ^a   Coelho, Otavio Rizzi ^a   Franchini, Kleber Gomes ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Cardiac function; Heart; Hypertrophy; Oxidative stress; Statins

Indexed keywords

3 NITROTYROSINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DRUG EFFECT; ENZYME SUBUNIT; HEART FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART MUSCLE; HEART RIGHT VENTRICLE; HEART VENTRICLE OVERLOAD; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STROMA;

ANIMALS; ANTIOXIDANTS; AORTA; CONSTRICTION; CORONARY VESSELS; ENZYME INDUCTION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERTROPHY, LEFT VENTRICULAR; ISOENZYMES; MALE; MEMBRANE TRANSPORT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH DEHYDROGENASE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PHOSPHOPROTEINS; PRESSURE; PROTEINS; RATS; RATS, WISTAR; SIMVASTATIN; TYROSINE; VENTRICULAR REMODELING;

EID: 2342473975     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000124252.43470.2c     Document Type: Article

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