Dichotomy in regioselective cross-coupling reactions of 6,8-dichloropurines with phenylboronic acid and methylmagnesium chloride: Synthesis of 6,8-di-substituted purines

Synthesis

Volumn , Issue 6, 2004, Pages 889-894

  Hocek, Michal ^a   Hocková, Dana ^a   Dvořáková, Hana ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

Cross coupling reactions; Iron; Nucleobases; Palladium; Purines

Indexed keywords

CATALYSIS; CHLORINE COMPOUNDS; MAGNESIUM COMPOUNDS; ORGANIC ACIDS; SUBSTITUTION REACTIONS;

NUCLEOPHILIC SUBSTITUTION; PHENYLBORONIC ACID; REGIOSELECTIVITY;

SYNTHESIS (CHEMICAL);

6 AMINO 8 METHYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 6 AMINO 8 METHYLPURINE; 6 BENZYL 8 METHYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 6 BENZYL 8 METHYLPURINE; 6 CHLORO 8 METHYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 6 CHLORO 8 METHYLPURINE; 6,8 DIMETHYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 6,8 DIMETHYLPURINE; 6,8 DIPHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 6,8 DIPHENYLPURINE; 8 AMINO 6 PHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 8 AMINO 6 PHENYLPURINE; 8 BENZYL 6 PHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 8 BENZYL 6 PHENYLPURINE; 8 CHLORO 6 PHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 8 CHLORO 6 PHENYLPURINE; 8 METHOXY 6 PHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 8 METHOXY 6 PHENYLPURINE; 8 METHYL 6 PHENYL 9 (TETRAHYDROPYRAN 2 YL)PURINE; 8 METHYL 6 PHENYLPURINE; 9 BENZYL 6 CHLOROMETHYLPURINE; BENZENEBORONIC ACID; BENZYL CHLORIDE; BROMIDE; IRON; MAGNESIUM CHLORIDE; METHYL CHLORIDE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CROSS COUPLING REACTION; DRUG SYNTHESIS; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 2342473773     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-816012     Document Type: Article

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