Synthesis and Pharmacological Evaluation of 3-(3,4-Dichlorophenyl)-1-indanamine Derivatives as Nonselective Ligands for Biogenic Amine Transporters

Journal of Medicinal Chemistry

Volumn 47, Issue 10, 2004, Pages 2624-2634

  Yu, Han ^a,e   Kim, Jong ^a   Folk, John E ^a   Tian, Xinrong ^a,d   Rothman, Richard B ^b   Baumann, Michael H ^b   Dersch, Christina M ^b   Flippen Anderson, Judith L ^c,f   Parrish, Damon ^c   Jacobson, Arthur E ^a   Rice, Kenner C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c NAVAL RESEARCH LABORATORY   (United States)

^d PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^e ELI LILLY AND COMPANY   (United States)

^f RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3,4 DICHLOROPHENYL) 1 INDANAMINE DERIVATIVE; 3 (3,4 DICHLOROPHENYL) 6 HYDROXY N METHYL 1 INDANAMINE; CENTRAL STIMULANT AGENT; DOPAMINE TRANSPORTER; INDAN DERIVATIVE; METHAMPHETAMINE; NORADRENALIN TRANSPORTER; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG FORMULATION; DRUG SCREENING; DRUG SYNTHESIS; NEUROTRANSMITTER RELEASE; NONHUMAN; RAT;

ANIMALS; AUTORADIOGRAPHY; BIOGENIC AMINES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; EXTRACELLULAR FLUID; INDANS; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; NUCLEUS ACCUMBENS; RATS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 2342446618     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0305873     Document Type: Article

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