A reappraisal of preoperative chemoradiation for localized pancreatic head ductal adenocarcinoma in a 5-year single-institution experience

Journal of Gastrointestinal Surgery

Volumn 8, Issue 4, 2004, Pages 502-510

  Moutardier, V ^a   Turrini, O ^b   Huiart, L ^b   Viret, F ^b   Giovannini, M H ^b   Magnin, V ^b   Lelong, B ^b   Bories, E ^b   Guiramand, J ^b   Sannini, A ^b   Giovannini, M ^b   Houvenaeghel, G ^b   Blache, J L ^b   Moutardier, J C ^b   Delpero, J R ^b  

^a INSTITUT PAOLI CALMETTES   (France)

^b NONE

Author keywords

neoadjuvant chemoradiation; Pancreatic ductal adenocarcinoma; pancreaticoduodenectomy; pathologic response

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PANCREAS CARCINOMA; PANCREAS DUCT; PANCREATICODUODENECTOMY; PATIENT SELECTION; PREOPERATIVE CARE; PREOPERATIVE RADIOTHERAPY; SURVIVAL RATE; SURVIVAL TIME; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; CARCINOMA, PANCREATIC DUCTAL; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PREOPERATIVE CARE; SURVIVAL RATE; TIME FACTORS;

EID: 2342425629     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gassur.2003.11.013     Document Type: Article

References (29)

1. Ghaneh P., Kawesha A., Howes N., Jones L., Neoptolemos J.P. Adjuvant therapy for pancreatic cancer. World J Surg. 23:1999;937-945
2. Snady H., Bruckner H., Cooperman A., Paradiso J., Kiefer L. Survival advantage of combined chemoradiotherapy compared with resection as the initial treatment of patients with regional pancreatic carcinoma. Cancer. 89:2000;316-327
3. Bramhall S.R., Allum W.H., Jones A.G., Allwood A., Cummins C., Neoptolemos J.P. Treatment and survival in 13, 560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study. Br J Surg. 82:1995;111-115
4. Du W., Touchette D., Vaitkevicious V.K., Peters W.P., Shields A.P. Cost analysis of pancreatic carcinoma treatment. Cancer. 89:2000;1917-1924
5. Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer. 59:1987;2006-2010
6. Spitz F.R., Abbruzzese J.L., Lee J.E., et al. Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. J Clin Oncol. 15:1997;928-937
7. Wanebo H.J., Glicksman A.S., Verzeridis M.P., et al. Preoperative chemotherapy, radiotherapy, and surgical resection of locally advanced pancreatic cancer. Arch Surg. 135:2000;81-87
8. White R.R., Hurwitz H.I., Morse M.A., et al. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas. Ann Surg Oncol. 8:2001;758-765
9. Breslin T.M., Hess K.R., Harbison D.B., et al. Neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreas: Treatment variables and survival duration. Ann Surg Oncol. 8:2001;123-132
10. Wolff R.A. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas: Great logic, grim reality. Ann Surg Oncol. 810:2001;747-748
11. Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 53:1958;457-481
12. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 50:1966;163-170
13. Monges G., Mathoulin-Portier M.P., Acres B., et al. Differential MUC 1. Expression in normal and neoplastic human pancreatic tissue. Am J Clin Pathol. 112:1999;635-640
14. Geer R.J., Brennan M.F. Resection of pancreatic adenocarcinoma: Pronostic indicators for survival. Am J Surg. 165:1993;68-73
15. Yeo C.J., Cameron J.L., Lillemoe K.D., et al. Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients. Ann Surg. 221:1995;721-733
16. Coia L., Hoffman J., Scher R., et al. Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum. Int J Radiat Oncol Biol Phys. 30:1994;161-167
17. Hoffman J.P., Weese J.L., Solin L.J., et al. A pilot study of preoperative chemoradiation for patients with localized adenocarcinoma of the pancreas. Am J Surg. 169:1995;71-77
18. Rich T.A., Evans D.B. Preoperative combined modality therapy for pancreatic cancer. World J Surg. 19:1995;264-269
19. Weese J.L., Nussbaum M.L., Paul A.R., et al. Increased resectability of locally advanced pancreatic and periampullary carcinoma with neoadjuvant chemoradiotherapy. Int J Pancreatol. 7:1990;177-185
20. Jessup J.M., Steele G. Jr., Mayer R.J., et al. Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg. 128:1993;559-564
21. Kamthan A.G., Morris J.C., Dalton J., et al. Combined modality therapy for stage II and stage III pancreatic carcinoma. J Clin Oncol. 15:1997;2920-2927
22. Pisters P.W., Hudec W.A., Lee J.E., et al. Preoperative chemoradiation for patients with pancreatic cancer: Toxicity of endobiliary stents. J Clin Oncol. 18:2000;860-867
23. Ishikawa O., Ohigashi H., Imaoka S., et al. Concomitant benefit of preoperative irradiation in preventing pancreas fistula formation after pancreatoduodenectomy. Arch Surg. 126:1991;885-889
24. Hoffman J.P., Lipsitz S., Pisansky T., et al. Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group Study. J Clin Oncol. 16:1998;317-323
25. Mehta V.K., Fisher G., Ford J.A., et al. Preoperative chemoradiation for marginally resectable adenocarcinoma of the pancreas. J GASTROINTEST SURG. 5:2001;27-35
26. Pingpank J.F., Hoffman J.P., Ross E.A., et al. Effect of preoperative chemoradiotherapy on surgical margin status of resected adenocarcinoma of the head of the pancreas. J GASTROINTEST SURG. 5:2001;121-130
27. Willet C.G., Lewandrowski K., Warshaw A.L., Efird J., Compton C.C. Resection margins in carcinoma of the head of the pancreas. Implication for radiation therapy. Ann Surg. 217:1993;144-148
28. Neoptolemos J.P., Stocken D.D., Dunn J.A., et al. Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial. Ann Surg. 234:2001;758-768
29. Pisters P.W., Wolff R.A., Janjan N.A. Preoperative paclitaxel and concurrent rapid-fractionation radiation for resectable pancreatic adenocarcinoma: Toxicities, histologic response rates, and event-free outcome. J Clin Oncol. 20:2002;2537-2544