The Shizosaccharomyces pombe homolog (SpMYH) of the Escherichia coli MutY is required for removal of guanine from 8-oxoguanine/guanine mispairs to prevent G:C to C:G transversions

Journal of Radiation Research

Volumn 46, Issue 2, 2005, Pages 205-214

  Doi, Takashi ^a   Yonekura, Shin Ichiro ^a   Tano, Keizo ^b   Yasuhira, Shinji ^b   Yonei, Shuji ^a   Zhang, Qiu Mei ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

8 Oxoguanine; Base Excision repair; Base substitution; MutY S; S. pombe

Indexed keywords

DNA; ESCHERICHIA COLI; IONIZING RADIATION; OLIGONUCLEOTIDES; PURIFICATION; REPAIR;

8-OXOGUANINE; BASE EXCISION REPAIRS; BASE SUBSTITUTION; DNA GLYCOSYLASE; E. COLI; FISSION YEAST; GUANINE; MUTY/S; REACTIVE OXYGEN SPECIES; S POMBE;

POSITIVE IONS;

ESCHERICHIA COLI; SCHIZOSACCHAROMYCES POMBE;

8 HYDROXYGUANINE; 8-HYDROXYGUANINE; BACTERIAL DNA; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; DRUG DERIVATIVE; GUANINE;

ARTICLE; BASE MISPAIRING; CHEMISTRY; DNA BASE COMPOSITION; DNA DAMAGE; DNA REPAIR; ENZYMOLOGY; GENETICS; SCHIZOSACCHAROMYCES;

BASE COMPOSITION; BASE PAIR MISMATCH; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; DNA, BACTERIAL; GUANINE; SCHIZOSACCHAROMYCES;

EID: 23244467798     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.46.205     Document Type: Article

References (55)

1. Ames, B. N., Shigenaga, M. K. and Hagen, T. M. (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA, 90: 7915-7922.
2. Halliwell, B., Gutteridge, J. M. C. (1990) Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol., 186: 1-85.
3. Fridovich, I. (1995) Superoxide radical and superoxide dismutases. Annu. Rev. Biochem., 64: 97-112.
4. von Sonntag, C. (1987) The chemical basis of radiation biology, Taylor and Francis, London.
5. Breen, A. P. and Murphy, J. A. (1995) Reactions of oxyl radicals with DNA. Free Radic. Biol. Med., 18: 1033-1077.
6. Cadet, J., Delatour, T., Douki, T., Gasparutto, D., Pouget, J.-P., Ravanat, J.-L. and Sauvaigo, S. (1999) Hydroxyl radicals and DNA base damage. Mutat. Res., 424: 9-21.
7. Cooke, M. S., Evans, M. D., Dizdaroglu, M. and Lunec, J. (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J., 17: 1195-1214.
8. Boiteux, S. and Radicella, J. P. (1999) Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress. Biochimie, 81: 59-67.
9. Grollman, A. P. and Moriya, M. (1993) Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet., 9: 246-249.
10. Wallace, S. S. (2002) Biological consequences of free radical-damaged DNA bases. Free Radical Biol. Med., 33: 1-14.
11. Hazra, T. K., Hill, J. W., Izumi, T. and Mitra, S. (2001) Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions. Prog. Nucleic Acids Res. Mol. Biol., 68: 193-205.
12. Michaels, M. L. and Miller, J. H. (1992) The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J. Bacteriol. 174: 6321-6325.
13. Eisen, J. A., and Hanawalt, P. C. (1999) A phylogenomic study of DNA repair genes, proteins, and processes. Mutat. Res., 435: 171-213.
14. Mitra, S., Izumi, T., Boldogh, I., Bhakat, K. K., Hill, J. W. and Hazra, T. K. (2002) Choreography of oxidative damage repair in mammalian genomes. Free Radical Biol. Med., 33: 15-28.
15. Gros, L., Saparbaev, M. K. and Laval, J. (2002) Enzymology of the repair of free radicals-induced DNA damage. Oncogene, 21: 8905-8925.
16. Bjelland, S. and Seeberg, E. (2003) Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat. Res., 531: 37-80.
17. Michaels, M. L., Pham, L., Cruz, C. and Miller, J. H. (1991) MutM, a protein that prevents G:C→T:A transversions, is formamidopyrimidine-DNA glycosylase. Nucleic Acids Res., 19: 3629-3632.
18. Tchou, J., Kasai, H., Shibutani, S., Chung, M.-H., Laval, J., Grollman, A. P. and Nishimura, S. (1991) 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity. Proc. Natl. Acad. Sci. USA, 88: 4690-4694.
19. Orimo, H., Mei, N., Boiteux, S., Tokura, Y. and Kasai, H. (2004) Analysis of 8-hydroxyguanine (8-OH-Gua) released from DNA by the formamidepyrimidine DNA glycosylase (Fpg) protein: a reliable method to estimate cellular oxidative stress. J. Radiat. Res., 45: 455-460.
20. Moriya, M., Ou, C., Bodepudi, V., Johnson, F., Takeshita, M. and Grollman, A. P. (1991) Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine. Mutat. Res., 254: 281-288.
21. Hsu, G. W., Ober, M., Carell, T. and Beese, L. S. (2004) Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Nature, 431: 217-221.
22. Gogos, A., Cillo, A. J., Clarke, N. D. and Lu, A-L. (1996) Specific recognition of A/G and A/7,8-dihydro-8-oxoguanine (8-oxoG) mismatches by Escherichia coli MutY: removal of the C-terminal domain preferentially affects A/8-oxoG recognition. Biochemistry, 35: 16665-16671.
23. McCann, J. A. and Berti, P. J. (2003) Adenine release is fast in MutY-catalyzed hydrolysis of G:A and 8-oxoG:A DNA mismatches. J. Biol. Chem., 278: 29587-29592.
24. Fromme, J. C., Banerjee, A., Huang, S. L. and Verdine, G. L. (2004) Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature, 427: 652-656.
25. Michaels, M. L., Cruz, C., Grollman, A. P. and Miller, J. H. (1992) Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc. Natl. Acad. Sci. USA, 89: 7022-7025.
26. Tajiri, T., Maki, H. and Sekiguchi, M. (1995) Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia col. Mutat. Res., 336: 257-267.
27. Fowler, R. G., White, S. J., Koyama, C., Moore, S. C., Dunn, R. L. and Schaaper, R. M. (2003) Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathways. DNA Repair, 2: 159-173.
28. Miller, J. H. and Michaels, M. (1996) Finding new mutator strains of Escherichia coli-a review. Gene, 179: 129-132.
29. Fleck, O., Kunz, C., Rudolph, C. and Kohli, J. (1998) The high mobility group domain protein Cmbl of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines. J. Biol. Chem., 273: 30398-30405.
30. Nakahara, T., Zhang, Q.-M., Hashiguchi, K. and Yonei, S. (2000) Identification of proteins of Escherichia coli and Saccharomyces cerevisiae that specifically bind to C/C mismatches in DNA. Nucleic Acids Res., 28: 2551-2556.
31. Akasaka, S. and Yamamoto, K. (1994) Hydrogen peroxide induces G:C to T:A and G:C to C:G transversions in the supF gene of Escherichia col. Mol. Gen. Genet., 243: 500-505.
32. Ono, T., Negishi, K. and Hayatsu, H. (1995) Spectra of superoxide-induced mutations in the lacI gene of a wild-type and a mutM strain of Escherichia coli K-12. Mutat. Res., 326: 175-183.
33. 2-induced mutagenesis in bacteria. Nucleic Acids Res., 29: 2899-2903.
34. McBride, T. J., Schneider, J. E., Floyd, R. A. and Loeb, L. A. (1992) Mutations induced by methylene blue light in single-stranded M13mp2. Proc. Natl. Acad. Sci. USA, 89: 6866-6870.
35. Kino, K., Saito, I. and Sugiyama, H. (1998) Product analysis of GG-specific photooxidation of DNA via electron transfer: 2-aminoimidazolone as a major guanine oxidation product. J. Am. Chem. Soc., 120: 7373-7374.
36. Zhang, Q.-M., Ishikawa, N., Nakahara, T. and Yonei, S. (1998) Escherichia coli MutY protein has a guanine-DNA glycosylase that acts on 7,8-dihydro-8-oxoguanine:guanine mispair to prevent spontaneous GC-CG transversions. Nucleic Acids Res., 26: 4669-4675.
37. Lu, A.-L. and Fawcett, W. P. (1998) Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe. J. Biol. Chem., 273: 25098-25105.
38. Chang, D.-Y. and Lu, A-L. (2002) Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe. J. Biol. Chem., 277: 11853-11858.
39. Cupples, C. G. and Miller, J. H. (1989) A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions. Proc. Natl. Acad. Sci. USA, 86: 5345-5349.
40. Chang, D.-Y., Gu, Y. and Lu, A.-L. (2001) Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide. Mol. Gen. Genomics, 266: 336-342.
41. Maki, H. and Sekiguchi, M. (1992) MutT protein specifically hydrolyzes a potent mutagenic substrate for DNA synthesis. Nature, 355: 273-275.
42. Tassotto, M. L. and Mathews, C. K. (2002) Assessing the metabolic function of the MutT 8-oxodeoxyguanosine triphosphate in Escherichia coli by nucleotide pool analysis. J. Biol. Chem., 277: 15807-15812.
43. Timms, A. R., Muriel, W. and Bridges, B. A. (1999) A umuD, C-dependent pathway for spontaneous G:C to C:G transversions in stationary phase Escherichia coli mutY. Mutat. Res., 435: 77-80.
44. Matsumoto, Y., Zhang, Q.-M., Takao, M., Yasui, A. and Yonei, S. (2001) Escherichia coli Nth and human hNTH1 DNA glycosylases are involved in removal of 8-oxoguanine from 8-oxoguanine/guanine mispairs in DNA. Nucleic Acids Res., 29: 1975-1981.
45. Sugiyama, H., Ikeda, S. and Saito, I. (1996) Remarkably stable parallel-stranded oligonucleotides containing 5-methylisocytosine and isoguanine. J. Am. Chem. Soc., 118: 9994-9995.
46. Duarte, V., Muller, J. G. and Burrows, C. J. (1999) Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res., 27: 496-502.
47. Kino, K. and Sugiyama, H. (2001) Possible cause of G:C→ C:G transversions mutation by guanine oxidation product, imidazolone. Chem. Biol., 8: 369-378.
48. Cadet, J., Berger, M., Buchno, G. W., Joshi, P. C., Raoul, S. and Ravanat, J.-L. (1994) 2,2-Diamino-4-[(3, 5-di-O-acetyl-2-deosy-β-D-erythro- pentofuranosyl)amino]-5-(2H)-oxazolone: a novel and predominant radical oxidation product of 3′, 5′-di-O-acetyl-2′-deoxyguanosine. J. Am. Chem. Soc., 116: 7403-7404.
49. Ikeda, H. and Saito, I. (1999) 8-Methoxydeoxyguanine as an effective precursor of 2-aminoimidazolone, a major guanine oxidation product in one-electron oxidation of DNA. J. Am. Chem. Soc., 121: 10836-10837.
50. Takimoto, K., Tano, K., Hashimoto, M., Hori, M., Akasaka, S. and Utsumi, H. (1999) Delayed transfection of DNA after riboflavin mediated photosensitization increases G:C to C:G transversions of supF gene in Escherichia coli mutY strain. Mutat. Res., 445: 93-98.
51. Ireland, C. M. (1989) Activated N-ras oncogenes in human neuroblastoma. Cancer Res., 49: 5530-5533.
52. Giaretti, W., Rapallo, A., Geido, E., Sciutto, A., Merlo, F., Risio, M. and Rossini, F. P. (1998) Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation. Am. J. Pathol., 153: 1201-1209.
53. McGoldrick, J. P., Yen, Y.-C., Solomon, M., Essigmann, J. M. and Lu, A.-L. (1995) Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair protein. Mol. Cell. Biol., 15: 989-996.
54. Slupska, M. M., Baikalov, C., Luther, W. M., Chiang, J.-H., Wei, Y.-F. and Miller, J. H. (1996) Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. J. Bacteriol., 178: 3885-3892.
55. Takao, M., Zhang, Q.-M., Yonei, S. and Yasui, A. (1999) Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanineDNA glycosylase. Nucleic Acids Res., 27: 3638-3644.