Synthesis of an N-acyl sulfamate analog of luciferyl-AMP: A stable and potent inhibitor of firefly luciferase

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 17, 2005, Pages 3860-3864

  Branchini, Bruce R ^a   Murtiashaw, Martha H ^a   Carmody, Jill N ^a   Mygatt, Emily E ^a   Southworth, Tara L ^a  

^a The Holleran Center for Community Action and Public Policy   (United States)

Author keywords

Acyl adenylate; Adenylate forming; Bioluminescence; Chymotrypsin; Firefly; Inhibitor; Limited proteolysis; Luciferase; Sulfamate; Sulfonamide

Indexed keywords

ADENOSINE PHOSPHATE; CHYMOTRYPSIN; ENZYME INHIBITOR; LUCIFERASE; SULFONAMIDE;

ARTICLE; BIOLUMINESCENCE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME ANALYSIS; PROTEIN DEGRADATION; SYNTHESIS;

ADENOSINE MONOPHOSPHATE; ANIMALS; DRUG STABILITY; FIREFLY LUCIFERIN; KINETICS; LUCIFERASES, FIREFLY; MOLECULAR MIMICRY; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS;

COLEOPTERA;

EID: 23244455097     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.115     Document Type: Article

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