Vascular calcification in patients with renal failure: Culprit or innocent bystander?

Cardiology Clinics

Volumn 23, Issue 3, 2005, Pages 373-384

  Dellegrottaglie, Santo ^a   Saran, Rajiv ^b   Rajagopalan, Sanjay ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FETUIN; MINERAL; OSTEOPROTEGERIN; PHOSPHATE; TIOPRONIN;

ATHEROSCLEROSIS; BLOOD VESSEL CALCIFICATION; BONE METABOLISM; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; DIALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; ELECTRON BEAM TOMOGRAPHY; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; MINERAL METABOLISM; MOLECULE; MORTALITY; MULTIDETECTOR COMPUTED TOMOGRAPHY; PATHOGENESIS; PATIENT; POPULATION; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; REVIEW; TREATMENT PLANNING; UREMIA;

ATHEROSCLEROSIS; CALCINOSIS; CHRONIC DISEASE; HUMANS; KIDNEY DISEASES; RISK FACTORS; VASCULAR DISEASES;

EID: 23244433984     PISSN: 07338651     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccl.2005.04.001     Document Type: Review

References (82)

1. El. Meguid, A. Nahas, and A.K. Bello Chronic kidney disease: the global challenge Lancet 365 9456 2005 331 340
2. J. Coresh, B.C. Astor, and T. Greene Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey Am J Kidney Dis 41 1 2003 1 12
3. N.B. Shulman, C.E. Ford, and W.D. Hall Prognostic value of serum creatinine and effect of treatment of hypertension on renal function. Results from the hypertension detection and follow-up program. The Hypertension Detection and Follow-up Program Cooperative Group Hypertension 13 5 Suppl 1989 I80 I93
4. G. Manjunath, H. Tighiouart, and H. Ibrahim Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community J Am Coll Cardiol 41 1 2003 47 55
5. L.F. Fried, M.G. Shlipak, and C. Crump Renal insufficiency as a predictor of cardiovascular outcomes and mortality in elderly individuals J Am Coll Cardiol 41 8 2003 1364 1372
6. M.G. Shlipak, P.A. Heidenreich, and H. Noguchi Association of renal insufficiency with treatment and outcomes after myocardial infarction in elderly patients Ann Intern Med 137 7 2002 555 562
7. A.S. Go, G.M. Chertow, and D. Fan Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization N Engl J Med 351 13 2004 1296 1305
8. M.J. Sarnak, A.S. Levey, and A.C. Schoolwerth Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention Circulation 108 17 2003 2154 2169
9. U. Schwarz, M. Buzello, and E. Ritz Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure Nephrol Dial Transplant 15 2 2000 218 223
10. P. Jungers, Z.A. Massy, and T.N. Khoa Incidence and risk factors of atherosclerotic cardiovascular accidents in predialysis chronic renal failure patients: a prospective study Nephrol Dial Transplant 12 12 1997 2597 2602
11. S.M. Moe, and N.X. Chen Calciphylaxis and vascular calcification: a continuum of extra-skeletal osteogenesis Pediatr Nephrol 18 10 2003 969 975
12. G.M. London, S.J. Marchais, and A.P. Guerin Arterial structure and function in end-stage renal disease Nephrol Dial Transplant 17 10 2002 1713 1724
13. K. Nitta, T. Akiba, and K. Suzuki Assessment of coronary artery calcification in hemodialysis patients using multi-detector spiral CT scan Hypertens Res 27 8 2004 527 533
14. H.C. Stary, A.B. Chandler, and R.E. Dinsmore A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association Circulation 92 5 1995 1355 1374
15. J.A. Beckman, J. Ganz, and M.A. Creager Relationship of clinical presentation and calcification of culprit coronary artery stenoses Arterioscler Thromb Vasc Biol 21 10 2001 1618 1622
16. H. Huang, R. Virmani, and H. Younis The impact of calcification on the biomechanical stability of atherosclerotic plaques Circulation 103 8 2001 1051 1056
17. H.M. Loree, R.D. Kamm, and R.G. Stringfellow Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels Circ Res 71 4 1992 850 858
18. M. Abedin, Y. Tintut, and L.L. Demer Vascular calcification: mechanisms and clinical ramifications Arterioscler Thromb Vasc Biol 24 7 2004 1161 1170
19. K. Bostrom, K.E. Watson, and S. Horn Bone morphogenetic protein expression in human atherosclerotic lesions J Clin Invest 91 4 1993 1800 1809
20. L.A. Fitzpatrick, A. Severson, and W.D. Edwards Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis J Clin Invest 94 4 1994 1597 1604
21. S.M. Moe, K.D. O'Neill, and D. Duan Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins Kidney Int 61 2 2002 638 647
22. C.M. Shanahan, N.R. Cary, and J.C. Metcalfe High expression of genes for calcification-regulating proteins in human atherosclerotic plaques J Clin Invest 93 6 1994 2393 2402
23. N.M. Hujairi, B. Afzali, and D.J. Goldsmith Cardiac calcification in renal patients: what we do and don't know Am J Kidney Dis 43 2 2004 234 243
24. C.M. Shanahan, N.R. Cary, and J.R. Salisbury Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification Circulation 100 21 1999 2168 2176
25. S. Jono, Y. Nishizawa, and A. Shioi Parathyroid hormone-related peptide as a local regulator of vascular calcification. Its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells Arterioscler Thromb Vasc Biol 17 6 1997 1135 1142
26. W.S. Simonet, D.L. Lacey, and C.R. Dunstan Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 2 1997 309 319
27. J.J. Kaden, S. Bickelhaupt, and R. Grobholz Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulate aortic valve calcification J Mol Cell Cardiol 36 1 2004 57 66
28. I. Avbersek-Luznik, I. Malesic, and I. Rus Increased levels of osteoprotegerin in hemodialysis patients Clin Chem Lab Med 40 10 2002 1019 1023
29. S. Jono, M.D. McKee, and C.E. Murry Phosphate regulation of vascular smooth muscle cell calcification Circ Res 87 7 2000 E10 E17
30. P. Ducy, R. Zhang, and V. Geoffroy Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 5 1997 747 754
31. N.X. Chen, K.D. O'Neill, and D. Duan Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells Kidney Int 62 5 2002 1724 1731
32. C.M. Giachelli Vascular calcification mechanisms J Am Soc Nephrol 15 12 2004 2959 2964
33. M. Ketteler, P. Bongartz, and R. Westenfeld Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study Lancet 361 9360 2003 827 833
34. R. Mehrotra, R. Westenfeld, and P. Christenson Serum fetuin-A in nondialyzed patients with diabetic nephropathy: relationship with coronary artery calcification Kidney Int 67 3 2005 1070 1077
35. A. Farzaneh-Far, D. Proudfoot, and P.L. Weissberg Matrix Gla protein is regulated by a mechanism functionally related to the calcium-sensing receptor Biochem Biophys Res Commun 277 3 2000 736 740
36. G. Luo, P. Ducy, and M.D. McKee Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein Nature 386 6620 1997 78 81
37. T. Wada, M.D. McKee, and S. Steitz Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin Circ Res 84 2 1999 166 178
38. S.A. Steitz, M.Y. Speer, and M.D. McKee Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification Am J Pathol 161 6 2002 2035 2046
39. C.M. Giachelli, N. Bae, and M. Almeida Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques J Clin Invest 92 4 1993 1686 1696
40. M.Y. Speer, M.D. McKee, and R.E. Guldberg Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo J Exp Med 196 8 2002 1047 1055
41. W.G. Goodman, G. London, and K. Amann Vascular calcification in chronic kidney disease Am J Kidney Dis 43 3 2004 572 579
42. J. Zimmermann, S. Herrlinger, and A. Pruy Inflammation enhances cardiovascular risk and mortality in hemodialysis patients Kidney Int 55 2 1999 648 658
43. P. Raggi Effects of excess calcium load on the cardiovascular system measured with electron beam tomography in end-stage renal disease Nephrol Dial Transplant 17 2 2002 332 335
44. W.G. Goodman, J. Goldin, and B.D. Kuizon Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis N Engl J Med 342 20 2000 1478 1483
45. J. Oh, R. Wunsch, and M. Turzer Advanced coronary and carotid arteriopathy in young adults with childhood-onset chronic renal failure Circulation 106 1 2002 100 105
46. S.M. Moe, K.D. O'Neill, and N. Fineberg Assessment of vascular calcification in ESRD patients using spiral CT Nephrol Dial Transplant 18 6 2003 1152 1158
47. R.A. O'Rourke, B.H. Brundage, and V.F. Froelicher American College of Cardiology/American Heart Association Expert Consensus document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease Circulation 102 1 2000 126 140
48. R.C. Cury, M. Ferencik, and U. Hoffmann Epidemiology and association of vascular and valvular calcium quantified by multidetector computed tomography in elderly asymptomatic subjects Am J Cardiol 94 3 2004 348 351
49. C.R. Becker, T. Kleffel, A. Crispin, and A. Knez Coronary artery calcium measurement: agreement of multirow detector and electron beam CT AJR Am J Roentgenol 176 5 2001 1295 1298
50. W. Stanford, B.H. Thompson, and T.L. Burns Coronary artery calcium quantification at multi-detector row helical CT versus electron-beam CT Radiology 230 2 2004 397 402
51. J. Horiguchi, H. Yamamoto, and Y. Akiyama Coronary artery calcium scoring using 16-MDCT and a retrospective ECG-gating reconstruction algorithm AJR Am J Roentgenol 183 1 2004 103 108
52. A.S. Agatston, W.R. Janowitz, and F.J. Hildner Quantification of coronary artery calcium using ultrafast computed tomography J Am Coll Cardiol 15 4 1990 827 832
53. T.Q. Callister, B. Cooil, and S.P. Raya Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method Radiology 208 3 1998 807 814
54. B. Ohnesorge, T. Flohr, and R. Fischbach Reproducibility of coronary calcium quantification in repeat examinations with retrospectively ECG-gated multisection spiral CT Eur Radiol 12 6 2002 1532 1540
55. J.A. Rumberger, and L. Kaufman A Rosetta stone for coronary calcium risk stratification: Agatston, volume, and mass scores in 11,490 individuals AJR Am J Roentgenol 181 3 2003 743 748
56. G. Sangiorgi, J.A. Rumberger, and A. Severson Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology J Am Coll Cardiol 31 1 1998 126 133
57. B.K. Nallamothu, S. Saint, and L.F. Bielak Electron-beam computed tomography in the diagnosis of coronary artery disease: a meta-analysis Arch Intern Med 161 6 2001 833 838
58. H. Yamamoto, D. Shavelle, and J. Takasu Valvular and thoracic aortic calcium as a marker of the extent and severity of angiographic coronary artery disease Am Heart J 146 1 2003 153 159
59. R.C. Cury, M. Ferencik, and U. Hoffmann Epidemiology and association of vascular and valvular calcium quantified by multidetector computed tomography in elderly asymptomatic subjects Am J Cardiol 94 3 2004 348 351
60. P. Raggi, T.Q. Callister, and B. Cooil Identification of patients at increased risk of first unheralded acute myocardial infarction by electron-beam computed tomography Circulation 101 8 2000 850 855
61. L.J. Shaw, P. Raggi, and E. Schisterman Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality Radiology 228 3 2003 826 833
62. P. Raggi, L.J. Shaw, and D.S. Berman Prognostic value of coronary artery calcium screening in subjects with and without diabetes J Am Coll Cardiol 43 9 2004 1663 1669
63. R.C. Detrano, N.D. Wong, and T.M. Doherty Coronary calcium does not accurately predict near-term future coronary events in high-risk adults Circulation 99 20 1999 2633 2638
64. Y. Arad, L.A. Spadaro, and K. Goodman Prediction of coronary events with electron beam computed tomography J Am Coll Cardiol 36 4 2000 1253 1260
65. P. Greenland, L. LaBree, and S.P. Azen Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals JAMA 291 2 2004 210 215
66. M.J. Pletcher, J.A. Tice, and M. Pignone What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk BMC Med 2 1 2004 31
67. P.G. O'Malley, A.J. Taylor, and J.L. Jackson Prognostic value of coronary electron-beam computed tomography for coronary heart disease events in asymptomatic populations Am J Cardiol 85 8 2000 945 948
68. I.B. Salusky, and W.G. Goodman Cardiovascular calcification in end-stage renal disease Nephrol Dial Transplant 17 2 2002 336 339
69. M.R. Davies, and K.A. Hruska Pathophysiological mechanisms of vascular calcification in end-stage renal disease Kidney Int 60 2 2001 472 479
70. J. Braun, M. Oldendorf, and W. Moshage Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients Am J Kidney Dis 27 3 1996 394 401
71. P. Raggi, A. Boulay, and S. Chasan-Taber Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease? J Am Coll Cardiol 39 4 2002 695 701
72. T. Shoji, M. Emoto, and T. Tabata Advanced atherosclerosis in predialysis patients with chronic renal failure Kidney Int 61 6 2002 2187 2192
73. R. Mehrotra, M. Budoff, and P. Christenson Determinants of coronary artery calcification in diabetics with and without nephropathy Kidney Int 66 5 2004 2022 2031
74. A.A. Haydar, N.M. Hujairi, and A.A. Covic Coronary artery calcification is related to coronary atherosclerosis in chronic renal disease patients: a study comparing EBCT-generated coronary artery calcium scores and coronary angiography Nephrol Dial Transplant 19 9 2004 2307 2312
75. R.L. Perlman, M. Kiser, and F. Finkelstein The longitudinal chronic kidney disease study: a prospective cohort study of predialysis renal failure Semin Dial 16 6 2003 418 423
76. M. Tamashiro, K. Iseki, and O.T. Sunagawa Significant association between the progression of coronary artery calcification and dyslipidemia in patients on chronic hemodialysis Am J Kidney Dis 38 1 2001 64 69
77. M.J. Budoff, K.L. Lane, and H. Bakhsheshi Rates of progression of coronary calcium by electron beam tomography Am J Cardiol 86 1 2000 8 11
78. M. Bursztyn, M. Motro, and E. Grossman Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation J Hypertens 21 10 2003 1953 1959
79. T.Q. Callister, P. Raggi, and B. Cooil Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography N Engl J Med 339 27 1998 1972 1978
80. T.P. Stompor, M. Pasowicz, and W. Sulowicz Trends and dynamics of changes in calcification score over the 1-year observation period in patients on peritoneal dialysis Am J Kidney Dis 44 3 2004 517 528
81. G.M. Chertow, S.K. Burke, and P. Raggi Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients Kidney Int 62 1 2002 245 252
82. G.M. London, A.P. Guerin, and S.J. Marchais Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality Nephrol Dial Transplant 18 9 2003 1731 1740