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Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 48, Issue 8, 2005, Pages 605-620

The synthesis of isotopically labeled (+)-2-amino-bicyclo[3.1.0]hexane-2,6- carboxylic acid and its 2-oxa-and 2-thia-analogs

(7) Wheeler, William J a O'Bannon, Douglas D a Kennedy, Joseph H a Monn, James A a Tharp Taylor, Roger W a Valli, Matthew J a Kuo, Fengjiun a

a ELI LILLY AND COMPANY (United States)

Author keywords

Bucherer Berg reaction; Carbon 14; mGlu agonist; Tritium

Indexed keywords

AMINO ACIDS; CARBON; KETONES; NITROGEN COMPOUNDS; SYNTHESIS (CHEMICAL); TRITIUM;

2-METHYLENE; 6-CARBOXYLIC ACID; BUCHERE-BERG REACTION; CARBON 14; GLUTAMIC ACID; ISOTOPICALLY LABELED; ISOTOPOMERS; METABOTROPIC GLUTAMATE RECEPTORS; MGLU AGONIST; SYNTHESISED;

HEXANE;

2 AMINOBICYCLO[3.1.0]HEXANE 2,6 CARBOXYLIC ACID; 2 OXABICYCLO[3.1.0]HEXANE 2,6 CARBOXYLIC ACID; 2 THIABICYCLO[3.1.0]HEXANE 2,6 CARBOXYLIC ACID; AMMONIUM CHLORIDE; AMMONIUM DERIVATIVE; CARBENE; CARBON 13; CARBON 14; GLUTAMIC ACID DERIVATIVE; HETEROCYCLIC COMPOUND; HYDANTOIN; KETONE; METABOTROPIC RECEPTOR AGONIST; NITROGEN 15; OXYGEN; POTASSIUM CYANIDE; SODIUM CARBONATE; SULFUR; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BUCHERER BERG REACTION; CHEMICAL REACTION; CHIRALITY; DRUG ABSORPTION; DRUG CONFORMATION; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG SYNTHESIS; HYDROLYSIS; IN VITRO STUDY; ISOTOPE LABELING; RACEMIC MIXTURE; STANDARD;

THIA;

EID: 22944460737 PISSN: 03624803 EISSN: None Source Type: Journal
DOI: 10.1002/jlcr.956 Document Type: Article

Times cited : (7)

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