Quinovic acid glycosides from Mitragyna stipulosa - First examples of natural inhibitors of snake venom phosphodiesterase I

Natural Product Letters

Volumn 16, Issue 6, 2002, Pages 389-393

  Fatima, Naheed ^a   Tapondjou, Leon Azefack ^a   Lontsi, David ^a   Sondengam, B L ^a   Atta Ur Rahman, ^a   Choudhary, M Iqbal ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Enzyme inhibition; Mitragyna stipulosa; Phosphodiesterase I; Quinovic acid glycosides

Indexed keywords

3 BETA ACETYL URSOLIC ACID; ALPHA AMYRIN; BETA SITOSTEROL GLUCOPYRANOSIDE; MITRAGYNA STIPULOSA EXTRACT; OLEANOLIC ACID; PHOSPHODIESTERASE I; PHOSPHODIESTERASE I INHIBITOR; PHOSPHODIESTERASE INHIBITOR; PLANT EXTRACT; QUINOVIC ACID; QUINOVIC ACID 3 O (BETA DEXTRO QUINOVOPYRANOSIDE) 27 O BETA DEXTRO GLUCOPYRANOSYL) ESTER; QUINOVIC ACID 3 O GLUCOPYRANOSIDE; QUINOVIC ACID GLYCOSIDE DERIVATIVE; QUINOVIN GLYCOSIDE C; SNAKE VENOM; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID;

ARTICLE; BARK; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME INHIBITION; EXTRACTION; MEDICINAL PLANT; MITRAGYNA STIPULOSA; NONHUMAN; PHYTOCHEMISTRY; RUBIACEAE; STRUCTURE ANALYSIS;

CAMEROON; GLUCOSIDES; MITRAGYNA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLEANOLIC ACID; PHOSPHODIESTERASE INHIBITORS; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; SNAKE VENOMS; STEREOISOMERISM; TRITERPENES;

EID: 0036890260     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575630290033169     Document Type: Article

References (17)

1. E.J. Shellard (1974). Bulletin on Narcotics, issue 2-004.
2. J. Vivien and J.J. Faure (1985). Arbres des Forests Denses d'Afrique Centrale, p. 378. Republique Francaise, Minitere des Relatiuons Exterieures, Cooperation et Technique, Paris.
3. F.R. Irvine (1961). Woody Plants of Ghana, pp. 685-686. Oxford University Press, London.
4. J.M. Wall and M.G. Breyer-Brandwijk (1962). The Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd Edn., p. 900. E. & S. Livingstone Ltd., Edinburgh.
5. P.J. Houghton, P.K. Lala, E.J. Shellard and K. Sarpong (1976). J. Pharm. Pharmacol., 28, 664-666.
6. H. Hiller (1987). Biologically Active Natural Products. In: K. Hostettmann and P. Lean (Eds.), p. 167. Oxford Science Publication, London.
7. B.M. Shashi, K.S. Sudip and G. Poddar (1988). Phytochemistry, 27, 3037-3067.
8. K.-T. Lee, I.C. Sohn, H.J. Park, D.W. Kim, G.O. Jung and K.Y. Park (2000). Planta Medica, 66, 329-332.
9. L.E. Lei-Ijo, K.C. Tsou, K.W. Lo, C.G. Lopez, M. Balasegaram and S. Ganesan (1980). Cancer, 45, 795-798.
10. R. Aquino, F. De Simone, C. Pizza and J.F. De Mello (1988). Phytochemistry, 27, 2927-2930.
11. M.E.O. Matos, M.P. Sousa, M.I.L. Machado and B.R. Filho (1986). Phytochemistry, 25, 1419-1422.
12. Dictionary of Natural Products (1994). Vol. 3, pp. 3243-3244. Chapman Hall Chemical Database, London.
13. R. Mamillapalli, R. Haimovitz, M. Ohad and M. Shinitzky (1998). FEBS Lett., 436, 256-258.
14. W.E. Razzell (1963). Methods in Enzymology, Vol. VI, pp. 236-242. Academic Press, New York.
15. W.E. Razzell and H.G. Khorana (1959). J. Biol. Chem., 234, 2105-2113.
16. T. Nakabayashi, Y. Matsuoka, H. Ikezawa and Kimura (1994). Int. J. Biochem., 26, 171-179.
17. J.L. Gomez, M.J. Costas, J.M. Ribeiro, A. Ferandez, A. Romero, M. Avalos and J.C. Cameselle (1998). FEBS Lett., 421, 77-79.