Perceptual thresholds and electrode impedance in three retinal prosthesis subjects

IEEE Transactions on Neural Systems and Rehabilitation Engineering

Volumn 13, Issue 2, 2005, Pages 201-206

  Mahadevappa, Manjunatha ^a   Weiland, James D ^b,c,e,f   Yanai, Douglas ^b,g   Fine, Ione ^c   Greenberg, Robert J ^d   Humayun, Mark S ^b,h,i  

^a UNIVERSITY OF KENTUCKY   (United States)

^b DOHENY EYE INSTITUTE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d Second Sight Medical Products Inc   (United States)

^e Doheny Retina Institute   (United States)

^f University of Southern California ^*  (United States)

^g USC ^*

^h UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

ⁱ IEEE

Author keywords

Electrical stimulation; Implantable medical device; Low vision; Neural prosthesis; Retinal prosthesis

Indexed keywords

ELECTRODE IMPEDANCE; PERCEPTION THRESHOLDS; RETINAL PROSTHESES; RETINITIS PIGMENTOSA;

ELECTRODES; EYE MOVEMENTS; IMPLANTS (SURGICAL); PLATINUM; PROSTHETICS;

SENSORY PERCEPTION;

ARTICLE; BLINDNESS; CASE REPORT; ELECTRODE; ELECTRONICS; ELECTROSTIMULATION; HUMAN; IMPEDANCE; OPTICAL COHERENCE TOMOGRAPHY; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; PROSTHESIS; RETINA; RETINA PROSTHESIS; RETINITIS PIGMENTOSA;

BLINDNESS; DIFFERENTIAL THRESHOLD; ELECTRIC IMPEDANCE; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; EQUIPMENT FAILURE ANALYSIS; MICROELECTRODES; PROSTHESIS DESIGN; RETINAL GANGLION CELLS; RETINITIS PIGMENTOSA; VISUAL PERCEPTION;

EID: 22544447400     PISSN: 15344320     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNSRE.2005.848687     Document Type: Article

References (25)

1. J. R. Heckenlively, J. Boughman, and L. Friedman, "Diagnosis and classification of retinitis pigmentosa," in Retinitis Pigmentosa, J. R. Heckenlively, Ed. Philadelphia, PA: Lippincott, 1988, p. 21.
2. E. Margalit and S. Sadda, "Retinal and optic nerve diseases," Artif. Organs, vol. 27, no. 11, pp. 963-974, 2003.
3. M. S. Humayun, J. D. Weiland, G. Fujii, R. J. Greenberg, R. Williamson, J. Little, B. Mech, V. Cimmarusti, G. van Boemel, G. Dagnelie, and E. de Juan Jr, "Visual perception in a blind subject with a chronic micro-electronic retinal prosthesis," Vis. Res., vol. 43, no. 24, pp. 2573-2581, 2003.
4. E. Zrenner, "Will retinal implants restore vision?," Science, vol. 295, no. 5557, pp. 1022-1025, Feb. 2002.
5. M. S. Humayun, E. J. de Juan, J. D. Weiland, G. Dagnelie, S. Katona, R. J. Greenberg, and S. Suzuki, "Pattern electrical stimulation of the human retina," Vis. Res., vol. 39, pp. 2569-2576, 1999.
6. J. F. Rizzo 3rd, J. Wyatt, J. Loewenstein, S. Kelly, D. Shire, and J. Wyatt, "Methods and perceptual thresholds for short-term electrical stimulation of human retina with microelectrode arrays," Invest Ophthalmol. Vis. Sci., vol. 44, no. 12, pp. 5355-5361, 2003.
7. A. Santos, M. S. Humayun, E. J. de Juan, R. J. Greenburg, M. J. Marsh, I. B. Klock, and A. H. Milam, "Preservation of the inner retina in retinitis pigmentosa. A morphometric analysis," Arch. Ophthalmol., vol. 115, no. 4, pp. 511-515, 1997.
8. M. S. Humayun, M. Prince, E. J. de Juan, Y. Barron, M. Moskowitz, I. B. Klock, and A. H. Milam, "Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa," Invest Ophthalmol. Vis. Sci., vol. 40, no. 1, pp. 143-148, 1999.
9. J. L. Stone, W. E. Barlow, M. S. Humayun, E. J. de Juan, and A. H. Milam, "Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa," Arch. Ophthalmol., vol. 110, no. 11, pp. 1634-1639, 1992.
10. R. E. Marc, B. W. Jones, C. B. Watt, and E. Strettoi, "Neural remodeling in retinal degeneration," Prog. Retin. Eye Res., vol. 22, no. 5, pp. 607-655, 2003.
11. D. Yanai, R. J. Lakhanpal, J. D. Weiland, M. Mahadevappa, G. van Boemel, G. Y. Fujii, R. J. Greenberg, S. Caffey, E. de Juan Jr, and M. S. Humayun, "The value of preoperative tests in the selection of blind patients for a permanent microelectronic implant," Trans. Amer. Ophth. Soc., vol. 101, pp. 43-50, 2004.
12. D. L. Tucci and J. K. Niparko, "Medical and surgical aspects of cochlear implantation," in Cochlear Implants Principles & Practices, J. K. Niparko, K. I. Kirk, and N. K. Mellon, Eds. Philadelphia, PA: Lippincott Williams & Wilkins, 2000, pp. 189-221.
13. A. B. Watson and J. G. Robson, "Discrimination at threshold: Labeled detectors in human vision," Vis. Res., vol. 21, no. 7, pp. 1115-1121, 2004.
14. R. J. Jensen, J. F. Rizzo, 3rd, O. R. Ziv, A. E. Grumet, and J. Wyatt, "Thresholds for activation of rabbit retinal ganglion cells with an ultrafine extracellular microelectrode," Invest. Ophthalmol. Vis. Sci., vol. 44, no. 8, pp. 3533-3543, 2004.
15. S. B. Brummer, L. S. Robblee, and F. T. Hambrecht, "Criteria for selecting electrodes for electrical stimulation: Theoretical and practical considerations," Ann. NY Acad. Sci., vol. 405, pp. 159-171, 1983.
16. X. Beebe and T. L. Rose, "Charge injection limits of activated iridium oxide electrodes with 0.2 ms pulses in bicarbonate buffered saline," IEEE Trans. Biomed. Eng., vol. 35, no. 6, pp. 494-495, June 1988.
17. J. S. Hayes, J. T. Yin, D. V. Piyathaisere, J. D. Weiland, M. S. Humayun, and G. Dagnelie, "Visually guided performance of simple tasks using simulated prosthetic vision," Artif. Organs, vol. 27, no. 11, pp. 1016-1028, 2003.
18. R. W. Thompson, G. D. Barnett, M. S. Humayun, and G. Dagnelie, "Facial recognition using simulated prosthetic pixelized vision," Invest. Ophthalmol Vis. Sci., vol. 44, no. 11, pp. 5035-5042, 2003.
19. J. D. Weiland, D. Guven, M. Magrhibi, C. Davidson, S. Pannu, M. Mahadevappa, P. Krulevtitch, R. A. Sanchez, and M. S. Humayun, "Chronic implantation of an inactive poly (dimethyl siloxane) electrode array in dogs," Invest. Ophthalmol. Vis. Sci., vol. 45, 2004.
20. P. Walter, P. Szurman, M. Vobig, H. Berk, H. C. Ludtke-Handjery, H. Richter, C. Mittermayer, K. Heimann, and B. Sellhaus, "Successful long-term implantation of electrically inactive epiretinal microelectrode arrays in rabbits," Retina, vol. 19, no. 6, pp. 546-552, 1999.
21. R. J. Jensen, O. R. Ziv, and J. F. Rizzo, 3rd, "Activation of rabbit retinal ganglion cells with large diameter electrodes: effects of pulse duration," Invest. Ophthalmol. Vis. Sci., vol. 45, 2004.
22. R. J. Greenberg, T. J. Velte, M. S. Humayun, G. Scarlatis, and E. de Juan, "A computational model of electrical stimulation of the retinal ganglion cell," IEEE Trans. Biomed. Eng., vol. 46, no. 5, pp. 505-514, May 1999.
23. J. S. Shyu, M. Maia, J. D. Weiland, M. S. Humayun, S. J. Chen, E. Margalit, S. Suzuki, E. de Juan, and D. V. Piyathaisere, "Electrical stimulation of isolated rabbit retina," in Proc. Biomedical Engineering Soc. Annu. Meeting, Seattle, WA, 2000.
24. J. P. Reilly, "Sensory responses to electrical stimulation," in Applied Bioelectricity: From Electrical Stimulation to Electropathology, J. P. Reilly, Ed. New York: Springer-Verlag, 1998, pp. 240-298.
25. D. P. McCreery, V. Pikov, A. Lossinksy, L. Bullara, and W. F. Agnew, "Arrays for chronic microstimulation of the lumbro-sacral spinal cord," IEEE Trans. Neural Syst. Rehab. Eng., vol. 12, no. 2, pp. 195-207,2004.