Successful long-term implantation of electrically inactive epiretinal microelectrode arrays in rabbits

Retina

Volumn 19, Issue 6, 1999, Pages 546-552

  Walter, Peter ^a   Szurman, Peter ^a   Vobig, Michael ^a   Berk, Hüsnü ^a   Lüdtke Handjery, Hans Christian ^b   Richter, Horst ^b   Mittermayer, Christian ^b   Heimann, Klaus ^a   Sellhaus, Bernd ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Electrical stimulation; Microelectrode array; Rabbit; Retinal prosthesis; Retinal tack; Retinitis pigmentosa; Vitrectomy; Vitreoretinal surgery

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATARACT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; LONG TERM CARE; MICROELECTRODE; NONHUMAN; POSTOPERATIVE COMPLICATION; PROSTHESIS FIXATION; RABBIT; RETINA; RETINA DETACHMENT; RETINA GANGLION CELL; TREATMENT OUTCOME; VISUAL PROSTHESIS;

EID: 0033506272     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006982-199919060-00012     Document Type: Article

References (21)

1. Karny H. Clinical and physiological aspects of the cortical visual prosthesis. Surv Ophthalmol 1997;20:47-58.
2. Sterling TD, Bering EA, Pollack SU, Vaughn HG, eds. Visual Prosthesis: The Interdisciplinary Dialogue. New York: Academic Press, 1971.
3. Dawson WW, Radtke ND. Stimulation of the vertebrate retina by indwelling electrodes. Invest Ophthalmol Vis Sci 1977;16: 249-252.
4. Chow AY, Chow VY. Subretinal electrical stimulation of the rabbit retina. Neurosci Lett 1997;225:13-16.
5. Zrenner E, Miliczek KD, Gabel VP, et al. The development of subretinal microphotodiodes for replacement of degenerated photoreceptors. Ophthalmic Res 1997;29:269-280.
6. Peyman G, Chow AY, Liang C, Chow VY, Perlman JI, Peachey NS. Subretinal semiconductor microphotodiode array. Ophthalmic Surg Lasers 1998;29:234-241.
7. Humayun MS, deJuan E, Dagnelie G, Greenberg RJ, Probst RH, Phillips DH. Visual perception elicited by electrical stimulation of retina in blind humans. Arch Ophthalmol 1996;114: 40-46.
8. Humayun MS, deJuan E, Greenberg RJ, Dagnelie G, Rader RS, Katona S. Electrical stimulation of the retina in patients with photoreceptor loss (abstract). Invest Ophthalmol Vis Sci 1997;38:S39.
9. Stone JL, Barlow WE, Humayun MS, deJuan E, Milam AH. Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa. Arch Ophthalmol 1992;110:1634-1639.
10. Eckmiller R. Retina implants with adaptive retina encoders. RESNA Research Symposium 1996:21-24.
11. Eckmiller R. Learning retina implants with epiretinal contacts. Ophthalmic Res 1997;29:281-289.
12. Rizzo JF, Wyatt J. Silicon retinal implant to aid patients suffering from certain forms of blindness. RESNA Research Symposium 1996:1-3.
13. Eckmiller R. Electronic simulation of the vertebrate retina. IEEE Trans Biomed Eng 1975;22:305-311.
14. Eckmiller R. Towards retina implants for improvement of vision in human with RP - challenges and first results. Proc WCNN 1995, INNS Press. Hillsdale, NJ: Lawrence Earlbaum, 1995:228-233.
15. Trieu HK, Ewe L, Mokwa W, Schwartz M, Hosticka BJ. Flexible silicon structures for a retina implant. Piscataway, NJ: IEEE Symposium Micro-electro Mechanical Systems, 1998: 515-519.
16. Stieglitz T, Blau C, Beutel H, Keller R, Meyer JU. Conception and development of flexible stimulator structures within a retinal implant system. Biomed Tech 1997;42(Suppl):458-459.
17. Miller B, Ryan SJ. Experimental vitrectomy. A lens-sparing technique in the rabbit eye. Arch Ophthalmol 1985;103:1382-1384.
18. Walter P, Szurman P, Berk H, Heimann K. Experimental implantation of devices for electrical retinal stimulation in rabbits - preliminary results. In: Green K, Edelhauser HF, Hackett RB, Hull DS, Potter DE, Tripathi RC, eds. Advances in Ocular Toxicology. New York: Plenum Press, 1997:113-120.
19. van der Zee WAM, Lean JS, Ryan SJ. Unexpected traction retinal detachment: a complication of an animal model of pars plana vitrectomy. Graefes Arch Clin Exp Ophthalmol 1984; 221:182-185.
20. Algvere P, Jahnberg P. Fibrovascular response to retinal tacks in the rabbit and monkey eye. Acta Ophthalmol 1990;68:543-548.
21. Bartz-Schmidt KU, Brunner R, Esser P, Lueke C, Walter P, Sickel W. The triple flash electroretinogram and its significance in macular diseases. Graefes Arch Clin Exp Ophthalmol 1996;234:604-611.