A computational model of electrical stimulation of the retinal ganglion cell

IEEE Transactions on Biomedical Engineering

Volumn 46, Issue 5, 1999, Pages 505-514

  Greenberg, Robert J ^a   Veite, Toby J ^a   Humayun, Mark S ^a   Scarlatis, George N ^a   De Juan Jr , Eugene ^a  

^a Johns Hopkins University   (United States)

Author keywords

Amphibian; Extracellular fields; Ganglion cell; Human; Modeling; Retina; Visual prosthesis

Indexed keywords

BIOELECTRIC POTENTIALS; CELL MEMBRANES; COMPUTATIONAL METHODS; ELECTRODES; FUNCTIONAL NEURAL STIMULATION; MATHEMATICAL MODELS;

HODGKIN-HUXLEY MODEL; RETINAL GANGLION CELL;

FUNCTIONAL ELECTRIC STIMULATION;

ARTICLE; ELECTRIC FIELD; ELECTROSTIMULATION; HUMAN; MATHEMATICAL ANALYSIS; RETINA GANGLION CELL; TARGET ORGAN; VISUAL PROSTHESIS;

ACTION POTENTIALS; ANIMALS; COMPUTER SIMULATION; ELECTRIC STIMULATION; ELECTRODES; ELECTROMAGNETIC FIELDS; ION CHANNELS; LINEAR MODELS; MODELS, NEUROLOGICAL; NECTURUS MACULOSUS; NONLINEAR DYNAMICS; RETINAL GANGLION CELLS;

EID: 0033007217     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/10.759051     Document Type: Article

References (41)

1. M. S. Humayun, E. de Juan, Jr., G. Dagnelie, R. J. Greenberg, R. Propst, and D. H. Phillips, Visual perception elicited by electrical stimulation of retina in blind humans," Arch. Ophthalmol., vol. 114, pp. 40-16, 1996.
2. J. Wyatt and J. Rizzo, Ocular implants for the blind," IEEE Spectrum, Mag. pp. 47-53, 1996.
3. J. I. Perlman, A. Y. Chow, and N. S. Peachey, Subretinal implantation of a high density microphotodiode array in the cat retina," Invest. Ophthalmol. Vis. Sei. Suppl., vol. 37, no. 3, p. S961996, Abstract.
4. W. Roush, Envisioning an artificial retina [news]," Sei., vol. 268, pp. 637-638, 1995.
5. R. J. Greenberg, M. S. Humayun, G. Dagnelie, R. S. Rader, and E. de Juan, Jr., Electrical stimulation of the human retina: An update," Invest. Ophthalmol. Vis. Sei. Suppl., vol. 36, no. 4, p. S-2341995, Abstract.
6. J. G. Flannery, D. B. Farber, A. C. Bird, and D. Bok, Degenerative changes in a retina affected with autosomal dominant retinitis pigmentosa," Invest. Ophthalmol. Vis. Sei., vol. 30, pp. 191-211, 1989.
7. J. L. Stone, W. E. Barlow, M. S. Humayun, E. de Juan, Jr., and A. H. Milam, Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa," Arch. Ophthalmol., vol. 110, pp. 1634-1639, 1992.
8. A. M. Potts, J. Inoue, and D. Buffum, The electrically evoked response of the visual system (EER)," Invest. Ophthalmol., vol. 7, pp. 269-278, 1968.
9. Y. Miyake, K. Yanagida, and K. Yagasaki, Visual function proximal to the photoreceptors in primary retinitis pigmentosa," Folia Ophthalmol. Jpn., vol. 32, pp. 302-308, 1981.
10. S. Kato, M. Saito, and T. Tanino, Response of the visual system evoked by an alternating current," Med. Biol. Eng. Comput., vol. 21, pp. 47-50, 1983.
11. Anonymous, Field defects in open-angle glaucoma," in Clinical Glaucoma, G. Gorin, Ed. New York: Marcel Dekker, 1977, pp. 111-123.
12. C. B. Toris, J. L. Eiesland, and R. F. Miller, Morphology of ganglion cells in the neotenous tiger salamander retina," J. Comp. Neural., vol. 352, pp. 535-559, 1995.
13. B. Coburn, Neural modeling in electrical stimulation [review]," Crit. Rev. Biomed. Eng., vol. 17, pp. 133-178, 1989.
14. J. T. Rubinstein and F. A. Spelman, Analytical theory for extracellular electrical stimulation of nerve with focal electrodes," Biophys. J., vol. 54, pp. 975-981, 1988.
15. R. Plonsey and R. C. Barr, Electric field stimulation of excitable tissue," IEEE Trans. Biomed. Eng., vol. 42, pp. 329-336, 1995.
16. L. Hause, A mathematical model for transmembrane potentials secondary to extracellular fields," in Electroanaesthesia: Biomédical and Biophysical Studies, A. J. Sances and S. J. Larson, Eds. New York: Academic, 1975, pp. 176-200.
17. W. Rail, Core conductor theory and cable properties of neurons," in Handbook of Physiology, J. M. Brookhart and V. B. Mountcastle, Eds. Bethesda, MD: Amer. Physiological Soc., 1977, pp. 39-97.
18. M. Hines, NEURON-A program for simulation of nerve equations," in Neural Systems: Analysis and Modeling, F. Eeckman, Ed. Norwell, MA: Kluwer Academic, 1993, pp. 127-136.
19. T. J. Veite and R. F. Miller, Dendritic integration in ganglion cells of the mudpuppy," Retina Visual Neurosci., vol. 12, pp. 165-175, 1995.
20. J. J. Capowski and M. J. Sedivee, Accurate computer reconstruction and graphics display of complex neurons utilizing state-of-the-art interactive techniques," Comput. Biomed. Res., vol. 14, pp. 518-532, 1981.
21. D. F. Wann, T. A. Woolsey, M. L. Dieker, and W. M. Cowan, An on-line digital computer system for the semi-automatic analysis of Golgi-impregnated neurons," IEEE Trans. Biomed. Eng., vol. 20, pp. 233-247, 1973.
22. P. A. Coleman and R. F. Miller, Measurement of passive membrane parameters with whole-cell recording from neurons in the intact amphibian retina," J. Neurophysiol., vol. 61, pp. 218-230, 1989.
23. F. Rattay, Electrical Nerve Stimulation: Theory, Experiments and Applications. New York: Springer-Verlag, 1990.
24. A. L. Hodgkin and A. F. Huxley, A quantitative description of membrane current and its application to conduction and excitation in nerve," J. Physiol., London, U.K., vol. 117, pp. 500-544, 1952.
25. J. F. Fohlmeister, P. A. Coleman, and R. F. Miller, Modeling the repetitive firing of retinal ganglion cells," Brain Res., vol. 510, pp. 343-345, 1990.
26. J. F. Fohlmeister and R. F. Miller, A comprehensive model of repetitive impulse encoding in retinal ganglion cells," Invest. Ophthalmol. Vis. Sei. Suppl, vol. 36, no. 4, pp. S-9301995, Abstract.
27. _, Mechanisms by which cell geometry controls repetitive impulse firing in retinal ganglion cells,"/ Neurophysiol., vol. 78, pp. 1948-1964, 1997.
28. R. Plonsey and R. C. Barr, Bioelectricity, A Quantitative Approach. New York: Plenum, 1988, pp. 285-286.
29. D. R. McNeal, Analysis of a model for excitation of myelinated nerve," IEEE Trans. Biomed. Eng., vol. BME-23, pp. 329-337, 1976.
30. L. A. Geddes and L. E. Baker, The specific resistance of biological material-A compendium of data for the biomédical engineer and physiologist," Med. Biol. Eng., vol. 5, pp. 271-293, 1967.
31. P. R. Wheater, H. G. Burkitt, and V. G. Daniels, Functional Histology, A Text and Color Atlas. Edinburgh, Scotland: Churchill Livingstone, 1995, pp. 318-329.
32. J. D. Wiley and J. G. Webster, Analysis and control of the current distribution under circular dispersive," Electrodes IEEE Trans. Biomed. Eng., vol. BME-29, pp. 381-385, 1982.
33. I. Segev, J. W. Fleshman, and R. E. Burke, Compartmental models of complex neurons," in Methods in Neuronal Modeling, C. Koch and I. Segev, Eds. Cambridge, MA: MIT Press, 1989, pp. 63-96.
34. P. L. Carras, P. A. Coleman, and R. F. Miller, Site of action potential initiation in amphibian retinal ganglion cells," J. Neurophysiol., vol. 67, pp. 292-304, 1992.
35. J. B. Ranck, Which elements are excited in electrical stimulation of mammalian central nervous system: A review," Brain Res., vol. 98, pp. 417-440, 1975.
36. J. W. Moore and M. Westerfield, Action potential propagation and threshold parameters in inhomogeneous regions of squid axons," J. Physiol., London, U.K., vol. 336, pp. 285-300, 1983.
37. M. Humayun, R. Propst, E. de Juan, Jr., K. McCormick, and D. Hickingbotham, Bipolar surface electrical stimulation of the vertebrate retina," Arch. Ophthalmol., vol. 112, pp. 110-116, 1994.
38. J. L. Wyatt, J. F. Rizzo, A. Grumet, D. Edell, and R. J. Jensen, Development of a silicon retinal implant: Epiretinal stimulation of retinal ganglion cells in the rabbit," Invest. Ophthalmol. Vis. Sei. SuppL, vol. 35, no. 4, p. 593, 1994, Abstract.
39. R. N. Weinreb, A. W. Dreher, A. Coleman, H. Quigley, B. Shaw, and K. Reiter, Histopathalogic validation of Fourier-ellipsometry measurements of retinal nerve fiber layer thickness," Arch. Ophthalmol., vol. 108, pp. 557-560, 1990.
40. J. E. Dowling, The Retina, An Approachable Part of the Brain. Cambridge, MA: Harvard Univ. Press, 1987, pp. 131-132.
41. J. Stone, F. Makarov, and H. Holländer, The glial ensheathment of the soma and axon hillock of retinal ganglion cells," Visual Neurosci., vol. 12, pp. 273-279, 1995.