Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys

Clinical and Experimental Allergy

Volumn 35, Issue 7, 2005, Pages 894-906

  Miller, Lisa A ^a,c   Hurst, S D ^b,d   Coffman, R L ^b,e   Tyler, N K ^a   Stovall, M Y ^a   Chou, D L ^a   Putney, L F ^a   Gershwin, L J ^a   Schelegle, E S ^a   Plopper, C G ^a   Hyde, D M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GENENTECH INC   (United States)

^e Dynavax Technologies Corporation   (United States)

Author keywords

CD25; Dendritic cell; Dermatophagoides farinae; Eosinophil; IgE; Lung; Primate; T lymphocyte

Indexed keywords

ALLERGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; IMMUNOGLOBULIN E; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; T6 ANTIGEN;

AIRWAY OBSTRUCTION; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DERMATOPHAGOIDES FARINAE; HELPER CELL; IMMUNOCOMPETENT CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; TRACHEA MUCOSA; TRACHEOBRONCHIAL TREE;

ANIMALS; ANTIGENS, CD1; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; CD4-POSITIVE T-LYMPHOCYTES; CHEMOKINES; CYTOKINES; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; EOSINOPHILS; FEMALE; IMMUNOGLOBULIN E; IMMUNOHISTOCHEMISTRY; MACACA MULATTA; RECEPTORS, CHEMOKINE; RECEPTORS, INTERLEUKIN-2; RESPIRATORY SYSTEM; RNA, MESSENGER;

EID: 22344446514     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02271.x     Document Type: Article

References (62)

1. Busse WW, Lemanske RF. Asthma. N Engl J Med 2001; 344: 350-62.
2. Tunon-De-Lara JM, Redington AE, Bradding P et al. Dendritic cells in normal and asthmatic airways: expression of the alpha subunit of the high affinity immunoglobulin E receptor (Fc epsilon RI-alpha). Clin Exp Allergy 1996; 26:648-55.
3. Moller GM, Overbeek SE, van Helden-Meeuwsen CG et al. Increased numbers of dendritic cells in the bronchial mucosa of atopic asthmatic patients: downregulation of inhaled corticosteroids. Clin Exp Allergy 1996; 26:517-24.
4. Bertorelli G, Bocchino V, Zhou X et al. Dendritic cell number is related to IL-4 expression in the airways of atopic asthmatic subjects. Allergy 2000; 55:449-54.
5. Azzawi M, Bradley B, Jeffery PK et al. Identification of activated T-lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990; 142:1407-13.
6. Bradley BL, Azzawi M, Jacobson M et al. Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness. J Allergy Clin Immunol 1991; 88:661-74.
7. Bentley AM, Meng Q, Robinson DS, Hamid Q, Kay AB, Durham SR. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics. Am J Respir Cell Mol Biol 1993; 8:35-42.
8. Bellini A, Vittori E, Marini M, Ackerman V, Mattoli S. Intraepithelial dendritic cells and selective activation of Th2-like lymphocytes in patients with atopic asthma. Chest 1993; 103: 997-1005.
9. Durham SR, Gould HJ, Thienes CP et al. Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid. Eur J Immunol 1997; 27:2899-906.
10. Wilson DR, Merrett TG, Varga EM et al. Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics. Am J Respir Crit Care Med 2002; 165:22-6.
11. Chung KF, Barnes PJ. Cytokines in asthma. Thorax 1999; 54:825-57.
12. Panina-Bordignon P, Papi A, Mariani M et al. The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J Clin Invest 2001; 107:1357-64.
13. Ying S, Meng Q, Zeibecoglou K et al. Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics. J Immunol 1999; 163:6321-9.
14. Haley KJ, Sunday ME, Wiggs BR et al. Inflammatory cell distribution within and along asthmatic airways. Am J Respri Crit Care Med 1998; 158:565-72.
15. Carroll N, Cooke C, James A. The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. Eur Respir J 1997; 10:292-300.
16. Hamid Q. Gross pathology and histopathology of asthma. J Allergy Clin Immunol 2003; 111:431-2.
17. Hamid Q, Song Y, Kotsimbos TC et al. Inflammation of small airways in asthma. J Allergy Clin Immunol 1997; 100: 44-51.
18. Minshall EM, Hogg JC, Hamid QA. Cytokine mRNA expression in asthma is not restricted to the large airways. J Allergy Clin Immunol 1998; 101:386-90.
19. Schelegle ES, Gershwin LJ, Miller LA et al. Allergic asthma induced in rhesus monkeys by house dust mite (dermatophadoides farinae). Am J Pathol 2001; 158:333-41.
20. Hyde DM, Miller LA, McDonald RJ et al. Neutrophils enhance clearance of necrotic epithelial cells in ozone-induced lung injury in rhesus monkeys. Am J Physiol 1999; 277:L1190-8.
21. Duan X, Buckpitt AR, Plopper CG. Variation in antioxidant enzyme activities in anatomic subcompartments within rat and rhesus monkey lung. Toxicol Appl Pharmacol 1993; 123:73-82.
22. Hurst SD, Muchamuel T, German DM et al. New IL-17 family members promote ThI or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 2002; 169:443-53.
23. Gundel RH, Kinkade P, Torcellini CA et al. Antigen-induced mediator release in primates. Am Rev Respir Dis 1991; 144:76-82.
24. Miadonna A, Tedeschi A, Brasca C, Folco G, Sala A, Murphy RC. Mediator release after endobronchial antigen challenge in patients with respiratory allergy. J Allergy Clin Immunol 1990; 85: 906-13.
25. Reimann KA, Waite BCD, Lee-Parritz DE et al. Use of human leukocyte-specific monoclonal antibodies for clinically immunophenotyping lymphocytes of rhesus monkeys. Cytometry 1994; 17:102-8.
26. Wagner G. E-cadherin: a distant member of the immunoglobulin superfamily. Science 1995; 267:342.
27. Wells E, Harper ST, Jackson CG, Mann J, Eady RP. Characterization of primate bronchoalveolar mast cells. I. IgE-dependent release of histamine, leukotrienes, and prostaglandins. J Immunol 1986; 137:3933-40.
28. Yasue M, Nakamura S, Yokota T, Okudaira H, Okumura Y. Experimental monkey model sensitized with mite antigen. Int Arch Allergy Immunol 1998; 115:303-11.
29. Plopper CG, Heidsiek JG, Weir AJ, George JA, Hyde DM. Tracheobronchial epithelium in the adult rhesus monkey: a quantitative histochemical and ultrastructural study. Am J Anat 1989; 184:31-40.
30. Plopper CG, Alley JL, Weir AJ. Differentiation of tracheal epithelium during fetal lung maturation in the rhesus monkey Macaca mulatta. Am J Anat 1986; 175:59-71.
31. Plopper CG, Weir AJ, Nishio SJ, Cranz DL, St George JA. Tracheal submucosal gland development in the rhesus monkey, Macaca mulatta: ultrastructure and histochemistry. Anat Embryol (Berl) 1986; 174:167-78.
32. Plopper C, George JS, Cardoso W, Wu R, Pinkerton K, Buckpitt A. Development of airway epithelium: patterns of expression for markers of differentiation. Chest 1992; 101:2S-5S.
33. Shortman K, Liu YJ. Mouse and human dendritic cell subtypes. Nat Rev Immunol 2002; 2:151-61.
34. Ordonez C, Ferrando R, Hyde DM, Wong HH, Fahy JV. Epithelial desquamation in asthma: artifact or pathology? Am J Respir Crit Care Med 2000; 162:2324-9.
35. Demedts IK, Brusselle GG, Vermaelen KY, Pauwels RA. Identification and characterization of human pulmonary dendritic cells. Am J Resp Cell Mol Biol 2005, 32:177-84.
36. Uchiyama T, Broder S, Waldmann TA. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac(+) cells. J Immunol 1981; 126:1393-403.
37. Mittler R, Rao P, Olini G et al. Activated human Be cells display a functional IL-2 receptor. J Immunol 1985; 134:2393-9.
38. Rand TH, Silberstein DS, Kornfeld H, Weller PF. Human eosinophils express functional interleukin 2 receptors. J Clin Invest 1991; 88:825-32.
39. H5, and indicates local clonal expansion, somatic mutation and isotype switch events. Immunology 1999; 98:646-51.
40. Crimi E, Scordamaglia A, Crimi P, Zupo S, Barocci S. Total and specific IgE in serum, bronchial lavage and bronchoalveolar lavage of asthmatic patients. Allergy 1983; 38:553-9.
41. Campbell AM, Vachier I, Chanez P et al. Expression of the high-affinity receptor for IgE on bronchial epithelial cells of asthmatics. Am J Respir Cell Mol Biol 1998; 19:92-7.
42. Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am Rev Respir Dis 1988; 137:62-9.
43. De Monchy JG, Kauffman HF, Venge P et al. Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions. Am Rev Respir Dis 1985; 131:373-6.
44. Hamid Q, Azzawi M, Ying S et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991; 87:1541-6.
45. Robinson DS, Ying S, Bentley AM et al. Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methucholine responsiveness in atopic asthma. J Allergy Clin Immunol 1993; 92:397-403.
46. Humbert M, Durham SR, Ying S et al. IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med 1996; 154:1497-504.
47. Humbert M, Corrigan CJ, Kimmitt P, Till SJ, Kay AB, Durham SR. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med 1997; 156:704-8.
48. Humbert M, Durham SR, Kimmitt P et al. Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J Allergy Clin Immunol 1997; 99:657-65.
49. Walter MJ, Kajiwara N, Karanja P, Castro M, Holtzman MJ. Interleukin 12 p40 production by barrier epithelial cells during airway inflammation. J Exp Med 2001; 193: 339-51.
50. Campbell JJ, Bowman EP, Murphy K et al. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3beta receptor CCR7. J Cell Biol 1998; 141:1053-9.
51. Sallusto F, Schaerli P, Loetscher P et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol 1998; 28:2760-9.
52. Julia V, Hessel EM, Malherbe L, Glaichenhaus N, O'Garra A, Coffman RL. A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. Immunity 2002; 16:271-83.
53. Salvi S, Babu K, Holgate S. Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? Am J Respir Crit Care Med 2001; 164:1343-6.
54. Synek M, Beasley R, Frew AJ et al. Cellular infiltration of the airways in asthma of varying severity. Am J Respir Crit Care Med 1996; 154:224-30.
55. Tulic MK, Christodoulopoulos P, Hamid Q. Small airway inflammation in asthma. Respir Res 2001; 2:333-9.
56. Wagner EM, Liu MC, Weinmann GG, Permutt S, Bleecker ER. Peripheral lung resistance in normal and asthmatic subjects. Am Rev Respir Dis 1990; 141:584-8.
57. Ingram RH Jr Physiological assessment of inflammation in the peripheral lung of asthmatic patients. Lung 1990; 168: 237-47.
58. Yanai M, Sekizawa K, Ohrui T, Sasaki H, Takishima T. Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure. J Appl Physiol 1992; 72: 1016-23.
59. Wagner EM, Bleecker ER, Permutt S, Liu MC. Direct assessment of small airways reactivity in human subjects. Am J Respir Crit Care Med 1998; 157:447-52.
60. Gosset P, Tillie-Leblond I, Janin A et al. Expression of E-selectin, ICAM-1 and VCAM-1 on bronchial biopsies from allergic and non-allergic asthmatic patients. Int Arch Allergy Immunol 1995; 106:69-77.
61. Ohkawara Y, Yamauchi K, Maruyama N et al. In situ expression of the cell adhesion molecules in bronchial tissues from asthmatics with air flow limitation: in vivo evidence of VCAM-1/VLA-4 interaction in selective eosinophil infiltration. Am J Respir Cell Mol Biol 1995; 12:4-12.
62. Bentley AM, Durham SR, Robinson DS et al. Expression of endothelial and leukocyte adhesion molecules interacellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma. J Allergy Clin Immunol 1993; 92:857-68.