Passive immunization against nicotine attenuates nicotine discrimination

Life Sciences

Volumn 70, Issue 23, 2002, Pages 2793-2798

  Malin, David H ^a   Alvarado, Candice L ^a   Woodhouse, Katherine S ^a   Karp, Hilary ^a   Urdiales, Evelyn ^a   Lay, Diana ^a   Appleby, Phillipa ^a   Moon, William D ^a   Ennifar, Sofiane ^b   Basham, Lisa ^b   Fattom, Ali ^b  

^a UNIVERSITY OF HOUSTON CLEAR LAKE   (United States)

^b Nabi Biopharmaceuticals   (United States)

Author keywords

Drug discrimination; Nicotine; Nicotine immunization

Indexed keywords

IMMUNOGLOBULIN G; NICOTINE; NICOTINE VACCINE; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; MALE; NONHUMAN; PASSIVE IMMUNIZATION; RAT; REST; STIMULATION; TASK PERFORMANCE; TASTE DISCRIMINATION;

ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING (PSYCHOLOGY); CUES; DISCRIMINATION LEARNING; FEMALE; IMMUNIZATION, PASSIVE; MALE; NICOTINE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE; SODIUM CHLORIDE;

ORYCTOLAGUS CUNICULUS;

EID: 0037177472     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01523-0     Document Type: Article

References (14)

1. Nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats
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5. Discriminability of nicotine in tobacco smoke: Implications for titration
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13. Relation of nicotine yield in cigarettes to blood nicotine concentrations in smokers
14. Laboratory and clinical evaluation of conjugate vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides bound to Pseudomonas aeruginosa recombinant exoprotein A