Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS

Experimental Cell Research

Volumn 308, Issue 1, 2005, Pages 18-28

  Kim, Shi Mun ^a   Kim, Rockki ^b   Ryu, Jae Hyun ^a   Jho, Eek Hoon ^b   Song, Ki Joon ^a   Jang, Shyh Ing ^c   Kee, Sun Ho ^a  

^a Korea University College of Medicine   (South Korea)

^b University of Seoul   (South Korea)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

AGS cells; E cadherin; Giant cell formation; ICAT; Wnt signaling; catenin

Indexed keywords

AXIN; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; MYC PROTEIN; UVOMORULIN; WNT PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL POPULATION; CELL STRUCTURE; CELL SURVIVAL; DOWN REGULATION; ENZYME ACTIVITY; GIANT CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STARVATION; STOMACH CANCER;

EID: 22244490683     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.04.002     Document Type: Article

References (52)

1. R.T. Moon, and D. Kimelman From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus BioEssays 20 1998 536 545
2. M. Peifer, and P. Polakis Wnt signaling in oncogenesis and embryogenesis-A look outside the nucleus Science 287 2000 1606 1609
3. R.H. Giles, J.H. van Es, and H. Clevers Caught up in a Wnt storm: Wnt signaling in cancer Biochim. Biophys. Acta, Rev. Cancer 1653 2003 1 24
4. R.T. Moon, A.D. Kohn, G.V. Ferrari, and A. Kaykas WNT and β-catenin signaling: disease and therapies Nat. Rev., Genet. 5 2004 691 701
5. K.M. Cadigan, and R. Nusse Wnt signaling: a common theme in animal development Genes Dev. 11 1997 3286 3305
6. P. Polakis Wnt signaling and cancer Genes Dev. 14 2000 1837 1851
7. P. Polakis Casein kinase 1: a Wnt'er of disconnect Curr. Biol. 12 2002 R499 R501
8. C. Jamora, and E. Fuchs Intercellular adhesion, signalling and the cytoskeleton Nat. Cell Biol. 4 2002 E101 E108
9. W.J. Nelson, and R. Nusse Convergence of Wnt, β-catenin, and cadherin pathways Science 303 2004 1483 1487
10. M. Takeichi Cadherin cell adhesion receptors as a morphogenetic regulator Science 251 1991 1451 1455
11. M. Takeichi Morphogenetic roles of classic cadherins Curr. Opin. Cell Biol. 7 1995 619 627
12. M. Takeichi Cadherins in cancer implications for invasion and metastasis Curr. Opin. Cell Biol. 5 1993 806 811
13. T. Oda, Y. Kanai, T. Oyama, K. Yoshiura, Y. Shimoyama, W. Birchmeier, T. Sugimura, and S. Hirohashi E-cadherin gene mutations in human gastric carcinoma cell lines Proc. Natl. Acad. Sci. U. S. A. 91 1994 1858 1862
14. K. Yoshiura, Y. Kanai, A. Ochiai, Y. Shimoyama, T. Sugimura, and S. Hirohashi Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas Proc. Natl. Acad. Sci. U. S. A. 92 1995 7416 7419
15. P. Guilford, J. Hopkins, J. Harraway, M. McLeod, N. McLeod, P. Harawira, H. Taite, R. Scoular, A. Miller, and A.E. Reeve E-cadherin germline mutations in familial gastric cancer Nature 392 1998 402 405
16. B. Ciruna, and J. Rossant FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak Dev. Cell 1 2001 37 49
17. M. Conacci-Sorrell, I. Simcha, T. Ben-Yedidia, J. Blechman, P. Savagner, and A. Ben-Ze'ev Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of β-catenin signaling, Slug, and MAPK J. Cell Biol. 163 2003 847 857
18. A.U. Jawhari, M. Noda, M.J. Farthing, and M. Pignatelli Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines Br. J. Cancer 80 1999 322 330
19. V. Horsley, and G.K. Pavlath Forming a multinucleated cell: molecules that regulate myoblast fusion Cells Tissues Organs 176 2004 67 78
20. B.H. Long, and C.R. Fairchild Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase Cancer Res. 54 1994 4355 4361
21. M. Jordan, R. Toso, D. Thrower, and L. Wilson Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations Proc. Natl. Acad. Sci. U. S. A. 90 1993 9552 9556
22. T.M. Illidge, M.S. Cragg, B. Fringes, P. Olive, and J.A. Erenpreisa Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage Cell Biol. Int. 24 2000 621 633
23. M. Nitta, H. Tsuiki, Y. Arima, K. Harada, T. Nishizaki, K. Sasaki, T. Mimori, Y. Ushio, and H. Saya Hyperploidy induced by drugs that inhibit formation of microtubule promotes chromosome instability Genes Cells 7 2002 151 162
24. J.L. Stow ICAT is a multipotent inhibitor of β-catenin. Focus on "Role for ICAT in β-catenin-dependent nuclear signaling and cadherin functions" Am. J. Physiol.: Cell Physiol. 286 2004 C745 C746
25. F. Fagotto, E.-h. Jho, L. Zeng, T. Kurth, T. Joos, C. Kaufmann, and F. Costantini Domains of Axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization J. Cell Biol. 145 1999 741 756
26. J. Lyu, F. Costantini, E.-h. Jho, and C.-k. Joo Ectopic expression of Axin blocks neuronal differentiation of embryonic carcinoma P19 cells J. Biol. Chem. 278 2003 13487 13495
27. S.-H. Kee, and P.M. Steinert Microtubule disruption in keratinocytes induces cell-cell adhesion through activation of endogenous E-cadherin Mol. Biol. Cell 12 2001 1983 1993
28. M.C. Hsieh, C.W. Wu, L.H. Wu, W.Y. Lui, F.K. Peng, and C.L. Yu Heat shock and cytokines modulate the expression of adhesion molecules on different human gastric cancer cell lines Int. J. Cancer 67 1996 690 694
29. T.-C. He, A.B. Sparks, C. Rago, H. Hermeking, L. Zawel, L.T. da Costa, P.J. Morin, B. Vogelstein, and K.W. Kinzler Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512
30. O. Tetsu, and F. McCormick β-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426
31. A. Peled, D. Schwartz, N.B. Elkind, R. Wolkowicz, R. Li, and V. Rotter The role of p53 in the induction of polyploidy of myelomonocytic leukemic M1/2 cells Oncogene 13 1996 1677 1685
32. P. Olive, J. Banath, and R. Durand Development of apoptosis and polyploidy in human lymphoblast cells as a function of the cell cycle at the time of irradiation Radiat. Res. 146 1996 595 602
33. R. Allman, R.J. Errington, and P.J. Smith Delayed expression of apoptosis in human lymphoma cells undergoing low-dose taxol-induced mitotic stress Br. J. Cancer 88 2003 1649 1658
34. A. Masuda, and T. Takahashi Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis Oncogene 21 2002 6884 6897
35. S.S. Taylor, and F. McKeon Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage Cell 89 1997 727 735
36. D.P. Cahill, C. Lengauer, J. Yu, G.J. Riggins, J.K. Willson, S.D. Markowitz, K.W. Kinzler, and B. Vogelstein Mutations of mitotic checkpoint genes in human cancers Nature 392 1998 300 303
37. H. Grabsch, S. Takeno, W.J. Parsons, N. Pomjanski, A. Boecking, H.E. Gabbert, and W. Mueller Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer-association with tumor cell proliferation J. Pathol. 200 2003 16 22
38. R. Bharadwaj, and H. Yu The spindle checkpoint, aneuploidy, and cancer Oncogene 23 2004 2016 2027
39. M. Melixetian, A. Ballabeni, L. Masiero, P. Gasparini, R. Zamponi, J. Bartek, J. Lukas, and K. Helin Loss of Geminin induces rereplication in the presence of functional p53 J. Cell Biol. 165 2004 473 482
40. W. Zhu, Y. Chen, and A. Dutta Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint Mol. Cell. Biol. 24 2004 7140 7150
41. S.I. Iida, T. Hirota, T. Morisaki, T. Marumoto, T. Hara, S. Kuninaka, S. Honda, K.I. Kosai, M. Kawasuji, D.C. Pallas, and H. Saya Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function Oncogene 23 2004 5266 5274
42. Y. Uetake, and G. Sluder Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint" J. Cell Biol. 165 2004 609 615
43. K. Rother, C. Johne, K. Spiesbach, U. Haugwitz, K. Tschop, M. Wasner, L. LKlei-Hitpass, T. Moroy, J. Mossner, and K. Engeland Identification of Tcf-4 as a transcriptional target of p53 signalling Oncogene 23 2004 3376 3384
44. K.B. Kaplan, A.A. Burds, J.R. Swedlow, S.S. Bekir, P.K. Sorger, and I.S. Nathke A role for the adenomatous polyposis coli protein in chromosome segregation Nat. Cell Biol. 3 2001 429 432
45. P. Fodde, J. Kuipers, C. Rosenberg, R. Smits, M. Kielman, C. Gaspar, J.H. van Es, C. Breukel, J. Wiegant, R.H. Giles, and H. Clevers Mutations in the APC tumour suppressor gene cause chromosomal instability Nat. Cell Biol. 3 2001 433 438
46. T. Sekiya, T. Nakamura, Y. Kazuki, M. Oshimura, K. Kohu, K.-i. Tago, S. Ohwada, and T. Akiyama Overexpression of Icat induces G2 arrest and cell death in tumor cell mutants for adenomatous polyposis coli, β-catenin, or axin Cancer Res. 62 2002 3322 3326
47. M. Creane, C.B. Seymour, S. Colucci, and C. Mothersill Radiobiological effects of docetaxel (Taxotere): a potential radiation sensitizer Int. J. Radiat. Biol. 75 1999 731 737
48. T. Koyama, K.-i. Tago, T. Nakamura, S. Ohwada, Y. Morishita, J. Yokota, and T. Akiyama Mutation and expression of the β-catenin-interacting protein ICAT in human colorectal tumors Jpn. J. Clin. Oncol. 32 2002 358 362
49. L. Ciani, O. Krylova, J. Smalley, T.C. CDale, and C. Salinas A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules J. Cell Biol. 164 2004 243 253
50. D.P. Hanger, K. Hughes, J.R. Woodgett, J.P. Brion, and B.H. Anderton Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase Neurosci. Lett. 147 1992 58 62
51. F.R. Lucas, R.G. Goold, P.R. Gordon-Weeks, and P.C. Salinas Inhibition of GSK-3b leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium J. Cell Sci. 111 1988 1351 1361
52. G. Morfini, G. Szebenyi, R. Elluru, N. Ratner, and S.T. Brady Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility EMBO J. 21 2002 281 293