메뉴 건너뛰기




Volumn 40, Issue 5, 2005, Pages 395-401

Difficulty and hot-points on pharmacokinetics studies of traditional Chinese medicine

Author keywords

High throughput screening; Metabonomics; Pharmacokinetics; Traditional Chinese medicine

Indexed keywords

HERBACEOUS AGENT;

EID: 22244465859     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (51)
  • 1
    • 84977865122 scopus 로고
    • Absorption, excretion and distribution of derivatives of anthraquinone from Rheum, Chinese traditional medicines
    • Chen QH. Absorption, excretion and distribution of derivatives of anthraquinone from Rheum, Chinese traditional medicines. Acta Pharm Sin, 1963,10(9):525-528.
    • (1963) Acta Pharm Sin , vol.10 , Issue.9 , pp. 525-528
    • Chen, Q.H.1
  • 3
    • 22244437685 scopus 로고    scopus 로고
    • Significance of pharmacokinetics in research and development of tradition Chinese medicines
    • Liu CX. Significance of pharmacokinetics in research and development of tradition Chinese medicines. Chin Tradit Herb Drugs, 2001,32:s16-17.
    • (2001) Chin Tradit Herb Drugs , vol.32
    • Liu, C.X.1
  • 5
    • 22244441902 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics and toxicology of active constituents isolated from Ginkgo biloba L.
    • Xiao PG, Liu CX. Pharmacology, pharmacokinetics and toxicology of active constituents isolated from Ginkgo biloba L. Asia J Drug Metab Pharmacokinet, 2001, 1(3):229-232.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.3 , pp. 229-232
    • Xiao, P.G.1    Liu, C.X.2
  • 6
    • 22244452100 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, toxicology and therapeutics of Radix Notoginseng
    • Xiao PG, Liu CX. Pharmacology, pharmacokinetics, toxicology and therapeutics of Radix Notoginseng. Asia J Drug Metab Pharmacokinet, 2001,1(1):70-76.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.1 , pp. 70-76
    • Xiao, P.G.1    Liu, C.X.2
  • 7
    • 22244472742 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics and toxicology of active constituents isolated from Radix Salviae multiorrhizae
    • Liu CX, Xiao PG. Pharmacology, pharmacokinetics and toxicology of active constituents isolated from Radix Salviae multiorrhizae. Asia J Drug Metab Pharmacokinet, 2001,1(3):221-228.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.3 , pp. 221-228
    • Liu, C.X.1    Xiao, P.G.2
  • 8
    • 22244477823 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, toxicology and clinical therapeutics of active constituents isolated from Berberis plant
    • Xiao PG, Liu CX. Pharmacology, pharmacokinetics, toxicology and clinical therapeutics of active constituents isolated from Berberis plant. Asian J Drug Metab Pharmacokinet, 2001,1(2):135-139.
    • (2001) Asian J Drug Metab Pharmacokinet , vol.1 , Issue.2 , pp. 135-139
    • Xiao, P.G.1    Liu, C.X.2
  • 9
    • 22244484833 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics and therapeutics of traditional Chinese medicine: Radix Glycyrrhiza
    • Xiao PG, Liu CX. Pharmacology, pharmacokinetics and therapeutics of traditional Chinese medicine: Radix Glycyrrhiza. Asia J Drug Metab Pharmacokinet, 2001,1(2):140-150.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.2 , pp. 140-150
    • Xiao, P.G.1    Liu, C.X.2
  • 10
    • 22244492388 scopus 로고    scopus 로고
    • Recent advance in metabolic chemistry of traditional Chinese medicine
    • Yang CM, Hou SX, Zhang ZR. Recent advance in metabolic chemistry of traditional Chinese medicine. Asia J Drug Metab Pharmacokinet, 2001,1(1):57-62.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.1 , pp. 57-62
    • Yang, C.M.1    Hou, S.X.2    Zhang, Z.R.3
  • 11
    • 22244479775 scopus 로고    scopus 로고
    • The advance in studies on pharmacokinetics of Ligustrazin in China
    • Liu YM, Chen H, Zeng FD. The advance in studies on pharmacokinetics of Ligustrazin in China. Asian J Drug Metab Pharmacokinet, 2001,1(3):217-220.
    • (2001) Asian J Drug Metab Pharmacokinet , vol.1 , Issue.3 , pp. 217-220
    • Liu, Y.M.1    Chen, H.2    Zeng, F.D.3
  • 12
    • 22244455502 scopus 로고    scopus 로고
    • Ethnopharmacology, pharmacology, pharmacokinetics, toxicology and therapeutics of Fructus Crataegi
    • Sun LQ. Ethnopharmacology, pharmacology, pharmacokinetics, toxicology and therapeutics of Fructus Crataegi. Asia J Drug Metab Pharmacokinet, 2002,2(4): 291-297.
    • (2002) Asia J Drug Metab Pharmacokinet , vol.2 , Issue.4 , pp. 291-297
    • Sun, L.Q.1
  • 14
    • 0015308962 scopus 로고
    • Relationships between dose, effect, time and biophasic drug levels
    • Smolen VF, Barile RG, Theophanous TG. Relationships between dose, effect, time and biophasic drug levels. J Pharm Sci, 1972,61(3):467-470.
    • (1972) J Pharm Sci , vol.61 , Issue.3 , pp. 467-470
    • Smolen, V.F.1    Barile, R.G.2    Theophanous, T.G.3
  • 15
    • 22244473421 scopus 로고
    • Perimary study on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with antipyretic model
    • Fu HY, Ho YZ, Zhou AX. Perimary study on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with antipyretic model. Pharmacol Clin Chin Mater Med, 1992,8(1):1-4.
    • (1992) Pharmacol Clin Chin Mater Med , vol.8 , Issue.1 , pp. 1-4
    • Fu, H.Y.1    Ho, Y.Z.2    Zhou, A.X.3
  • 16
    • 22244473421 scopus 로고
    • Re-studies on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with diaphoretic model
    • Fu HY, Ho YZ, Zhou AX. Re-studies on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with diaphoretic model. Pharmacol Clin Chin Mater Med, 1992,8(5):1-4.
    • (1992) Pharmacol Clin Chin Mater Med , vol.8 , Issue.5 , pp. 1-4
    • Fu, H.Y.1    Ho, Y.Z.2    Zhou, A.X.3
  • 17
    • 22244473421 scopus 로고
    • Re-studies on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with anti-inflammation model
    • Fu HY, Ho YZ, Zhou AX. Re-studies on pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method with anti-inflammation model. Pharmacol Clin Chin Mater Med, 1993,9(2):1-4.
    • (1993) Pharmacol Clin Chin Mater Med , vol.9 , Issue.2 , pp. 1-4
    • Fu, H.Y.1    Ho, Y.Z.2    Zhou, A.X.3
  • 18
    • 22244489139 scopus 로고
    • Re-studies of pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method
    • Fu HY, Zhou AX, Ho YZ. Re-studies of pharmacokinetics of Ma-huang-tang, Gui-zhi-tang, Ying-Qiao-san and Sang-Ju-yin by phamracodynamic method. J Chin Patent Drugs, 1993,15(1):35-38.
    • (1993) J Chin Patent Drugs , vol.15 , Issue.1 , pp. 35-38
    • Fu, H.Y.1    Zhou, A.X.2    Ho, Y.Z.3
  • 19
    • 22244485130 scopus 로고
    • Calcilation of half-life by death ratio method
    • Hao MS, ZhanLM, Ge JY. Calcilation of half-life by death ratio method. Acta Pharmacol Sin, 1985,6(3):213-215.
    • (1985) Acta Pharmacol Sin , vol.6 , Issue.3 , pp. 213-215
    • Hao, M.S.1    Zhan, L.M.2    Ge, J.Y.3
  • 20
    • 22244432926 scopus 로고    scopus 로고
    • Determination of toxicokinetic parameters of Guan-mu-tong
    • Long SJ, Xu LB, Qiu Y. Determination of toxicokinetic parameters of Guan-mu-tong. Pharmacol Clin Chin Mater Med, 2003,19(1):19-22.
    • (2003) Pharmacol Clin Chin Mater Med , vol.19 , Issue.1 , pp. 19-22
    • Long, S.J.1    Xu, L.B.2    Qiu, Y.3
  • 21
    • 0031657920 scopus 로고    scopus 로고
    • Study on toxicokinetics of Wu-tou ingjection in mice
    • HuangYM, Pan LH, Wu XF. Study on toxicokinetics of Wu-tou ingjection in mice. J Chin Pharmaceut, 1998,33(7):421-423.
    • (1998) J Chin Pharmaceut , vol.33 , Issue.7 , pp. 421-423
    • Huang, Y.M.1    Pan, L.H.2    Wu, X.F.3
  • 22
    • 0035937452 scopus 로고    scopus 로고
    • Pharmacokinetics of tetramethylpyrazine in rat blood and brain using microdialysis
    • Tai TH, Liang CC. Pharmacokinetics of tetramethylpyrazine in rat blood and brain using microdialysis. Int J Pharmaceut, 2001,216:61-65.
    • (2001) Int J Pharmaceut , vol.216 , pp. 61-65
    • Tai, T.H.1    Liang, C.C.2
  • 23
    • 84977827320 scopus 로고    scopus 로고
    • Pharmacokinetic study of Shao-yao and Gan-cao decoctionin rats
    • Xiang QJ, Cheng G, Chen JM. Pharmacokinetic study of Shao-yao and Gan-cao decoctionin rats. J Chin Pharmaceut, 2000,30(4):384-386.
    • (2000) J Chin Pharmaceut , vol.30 , Issue.4 , pp. 384-386
    • Xiang, Q.J.1    Cheng, G.2    Chen, J.M.3
  • 24
    • 22244433269 scopus 로고    scopus 로고
    • On significance of gastroenterouos pharmacokinetics
    • Yang K, Pu XF. On significance of gastroenterouos pharmacokinetics. Chin J Exper Rescript, 1998,4(1):36-39.
    • (1998) Chin J Exper Rescript , vol.4 , Issue.1 , pp. 36-39
    • Yang, K.1    Pu, X.F.2
  • 25
    • 1642427350 scopus 로고
    • Effect of shassaikoto, a Japanese and Chinese herbal medicinal mixture, on the mitogentic activity of Lipopolysaccharide. A new pharmacological tesing method
    • Hiroko I, Sakae A, Yukio O. Effect of shassaikoto, a Japanese and Chinese herbal medicinal mixture, on the mitogentic activity of Lipopolysaccharide.. A new pharmacological tesing method. J Ethnopharmacol, 1987,211(1):45-50.
    • (1987) J Ethnopharmacol , vol.211 , Issue.1 , pp. 45-50
    • Hiroko, I.1    Sakae, A.2    Yukio, O.3
  • 26
    • 22244474388 scopus 로고    scopus 로고
    • Serum pharmacological application in pharmacokinetic studies of complex traditional Chinese medicines
    • Ma J, Tang Z, Li ZQ. Serum pharmacological application in pharmacokinetic studies of complex traditional Chinese medicines. Pharmacol Clin Chin Mater Med, 1999,15(1):44-48.
    • (1999) Pharmacol Clin Chin Mater Med , vol.15 , Issue.1 , pp. 44-48
    • Ma, J.1    Tang, Z.2    Li, Z.Q.3
  • 28
    • 1642590910 scopus 로고    scopus 로고
    • The concepts of recipe-derived component spectrum and target component in vivo/serum and their significance
    • Huang X. The concepts of recipe-derived component spectrum and target component in vivo/serum and their significance. J Fourth Mil Med Univ, 1999,20(4):277-280.
    • (1999) J Fourth Mil Med Univ , vol.20 , Issue.4 , pp. 277-280
    • Huang, X.1
  • 29
    • 0034620261 scopus 로고    scopus 로고
    • Herb-drug interactions
    • Fugh-Berman A. Herb-drug interactions. Lancet, 2000,355(9198):134-138.
    • (2000) Lancet , vol.355 , Issue.9198 , pp. 134-138
    • Fugh-Berman, A.1
  • 30
    • 85015564429 scopus 로고    scopus 로고
    • Herbal Supplements: Indications, Clinical Concerns, and Safety
    • Fugh-Berman A. Herbal Supplements: Indications, Clinical Concerns, and Safety. Nutr Today, 2002, 37(3):122-124.
    • (2002) Nutr Today , vol.37 , Issue.3 , pp. 122-124
    • Fugh-Berman, A.1
  • 31
    • 0035512382 scopus 로고    scopus 로고
    • Herb-drug interactions: Review and assessment of report reliability
    • Fugh-Berman A, Ernst E. Herb-drug interactions: review and assessment of report reliability. Br J Clin Pharmacol, 2001,52(5):587-595.
    • (2001) Br J Clin Pharmacol , vol.52 , Issue.5 , pp. 587-595
    • Fugh-Berman, A.1    Ernst, E.2
  • 32
    • 0033661825 scopus 로고    scopus 로고
    • Herb-drug interactions: Potentially important but woefully under-researched
    • Ernst E. Herb-drug interactions: potentially important but woefully under-researched. Eur J Clin Pharmacol, 2000,56(8):523-524.
    • (2000) Eur J Clin Pharmacol , vol.56 , Issue.8 , pp. 523-524
    • Ernst, E.1
  • 33
    • 0026096161 scopus 로고
    • A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagenicity testing
    • Crespi CL, Gonzalez FJ, Steimel DT, et al. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chem Res Toxicol, 1991,4(5):566-572.
    • (1991) Chem Res Toxicol , vol.4 , Issue.5 , pp. 566-572
    • Crespi, C.L.1    Gonzalez, F.J.2    Steimel, D.T.3
  • 34
    • 0033974910 scopus 로고    scopus 로고
    • Ginkgo biloba: A living fossil
    • 32
    • Jacobs BP, Browner WS. Ginkgo biloba: a living fossil. Am J Med, 2000,108(4):341-342(32).
    • (2000) Am J Med , vol.108 , Issue.4 , pp. 341-342
    • Jacobs, B.P.1    Browner, W.S.2
  • 36
    • 0033811070 scopus 로고    scopus 로고
    • Interaction of drugs and Chinese herbs: Pharmacokinetic changes of tolbutamide and diazepam caused by extract of Angelica dahurica
    • 34
    • Ishihara K, Kushida H, Yuzurihara M, et al. Interaction of drugs and Chinese herbs: pharmacokinetic changes of tolbutamide and diazepam caused by extract of Angelica dahurica. J Pharm Pharmacol, 2000,52(8): 1023-1029. (34)
    • (2000) J Pharm Pharmacol , vol.52 , Issue.8 , pp. 1023-1029
    • Ishihara, K.1    Kushida, H.2    Yuzurihara, M.3
  • 37
    • 0033866180 scopus 로고    scopus 로고
    • Grapefruit juice-felodipine interaction in the elderly
    • 35
    • Dresser GK, Bailey DG, Carruthers SG. Grapefruit juice-felodipine interaction in the elderly. Clin Pharmacol Ther, 2000,68(1):28-34(35).
    • (2000) Clin Pharmacol Ther , vol.68 , Issue.1 , pp. 28-34
    • Dresser, G.K.1    Bailey, D.G.2    Carruthers, S.G.3
  • 40
    • 85026138107 scopus 로고    scopus 로고
    • Herbal interactions with cardiovascular drugs
    • Awang DV, Fugh-Berman A. Herbal interactions with cardiovascular drugs. J Cardiovasc Nurs, 2002,16 (4):64-70.
    • (2002) J Cardiovasc Nurs , vol.16 , Issue.4 , pp. 64-70
    • Awang, D.V.1    Fugh-Berman, A.2
  • 41
    • 0344088459 scopus 로고    scopus 로고
    • Siberian ginseng (Elecutheroccus senticosus) effects on CYP2D6 and CYP3A4 activity in normal volunteers
    • Donovan JL, DeVane CL, Chavin KD, Taylor RM, Markowitz JS. Siberian ginseng (Elecutheroccus senticosus) effects on CYP2D6 and CYP3A4 activity in normal volunteers. Drug Metab Dispos, 2003,31 (5):519-522.
    • (2003) Drug Metab Dispos , vol.31 , Issue.5 , pp. 519-522
    • Donovan, J.L.1    DeVane, C.L.2    Chavin, K.D.3    Taylor, R.M.4    Markowitz, J.S.5
  • 42
    • 0036206368 scopus 로고    scopus 로고
    • In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1
    • Chang TK, Chen J, Benetton SA. In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1. Drug Metab Dispos, 2002,30(4): 378-384.
    • (2002) Drug Metab Dispos , vol.30 , Issue.4 , pp. 378-384
    • Chang, T.K.1    Chen, J.2    Benetton, S.A.3
  • 43
    • 0037025060 scopus 로고    scopus 로고
    • In vivo effects of Panax ginseng extracts on the cytochrome P450-dependent monooxygenase system in the liver of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-exposed guinea pig
    • Lee HC, Hwang SG, Lee YG, et al. In vivo effects of Panax ginseng extracts on the cytochrome P450-dependent monooxygenase system in the liver of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-exposed guinea pig. Life Sci, 2000,71(7):759-769.
    • (2000) Life Sci , vol.71 , Issue.7 , pp. 759-769
    • Lee, H.C.1    Hwang, S.G.2    Lee, Y.G.3
  • 44
    • 42749094526 scopus 로고    scopus 로고
    • Study on influence of ginsenoside Re on cytochrome P450 isoforms by cocktail approach using probe drugs, caffeine, chlorzoxazone, omeprazole and dapsone in rats
    • Fan HR, He F, Li QS, et al. Study on influence of ginsenoside Re on cytochrome P450 isoforms by cocktail approach using probe drugs, caffeine, chlorzoxazone, omeprazole and dapsone in rats. Asia J Drug Metab Pharmacokinet, 2004,4(3):177-186.
    • (2004) Asia J Drug Metab Pharmacokinet , vol.4 , Issue.3 , pp. 177-186
    • Fan, H.R.1    He, F.2    Li, Q.S.3
  • 45
    • 22244449739 scopus 로고    scopus 로고
    • CY3A4 and P-glycoprotein in small intestinal epithelial cells and their affects to some oral drugs
    • Yu LS, Zeng S. CY3A4 and P-glycoprotein in small intestinal epithelial cells and their affects to some oral drugs. Asia J Drug Metab Pharmacokinet, 2001,1 (4):305-312.
    • (2001) Asia J Drug Metab Pharmacokinet , vol.1 , Issue.4 , pp. 305-312
    • Yu, L.S.1    Zeng, S.2
  • 46
    • 0033739725 scopus 로고    scopus 로고
    • Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine
    • Hiroshi S, Yuchi S. Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine. Eur J Pharm Sci, 2000,12(1):3-12.
    • (2000) Eur J Pharm Sci , vol.12 , Issue.1 , pp. 3-12
    • Hiroshi, S.1    Yuchi, S.2
  • 47
    • 0042338519 scopus 로고    scopus 로고
    • So what's the deal with metabonomics?
    • Lindon JC, Holmes E, Nicholson JK. So what's the deal with metabonomics?. Anal Chem, 2003,75(17): 384A-391A.
    • (2003) Anal Chem , vol.75 , Issue.17
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 48
    • 22244451442 scopus 로고    scopus 로고
    • Significance of metabonomics in drug discovery and development
    • Liu CX, Li C, Lin DH, et al. Significance of metabonomics in drug discovery and development. Asia J Drug Metab Pharmacokinet, 2004,4(2):87-96.
    • (2004) Asia J Drug Metab Pharmacokinet , vol.4 , Issue.2 , pp. 87-96
    • Liu, C.X.1    Li, C.2    Lin, D.H.3
  • 49
    • 22244449060 scopus 로고    scopus 로고
    • Metabonomics in drug discovery and development [A]. He FC
    • Beijnig: Beijing Military Medical Press
    • Liu CX. Metabonomics in drug discovery and development [A]. He FC. New Drug Discovery in Postgene Time [M]. Beijnig: Beijing Military Medical Press, 2004. 17-20.
    • (2004) New Drug Discovery in Postgene Time [M] , pp. 17-20
    • Liu, C.X.1
  • 50
    • 22244437994 scopus 로고    scopus 로고
    • Significance of metabonomics in modern research of tradition Chinese medicines
    • Liu CX. Significance of metabonomics in modern research of tradition Chinese medicines. Chin Tradit Herb Drugs, 2004,35(6):601-605.
    • (2004) Chin Tradit Herb Drugs , vol.35 , Issue.6 , pp. 601-605
    • Liu, C.X.1
  • 51
    • 22244439625 scopus 로고    scopus 로고
    • Studies on pharmacodynamics and its biochemical mechanism of Ucncariastem mixture for treating children's hyperactivity syndrome by metabonomic method
    • Huang YR, Wei GL, Xiao SH, et al. Studies on pharmacodynamics and its biochemical mechanism of Ucncariastem mixture for treating children's hyperactivity syndrome by metabonomic method. Chin Tradit Herb Drugs, 2005,36(3):301-305.
    • (2005) Chin Tradit Herb Drugs , vol.36 , Issue.3 , pp. 301-305
    • Huang, Y.R.1    Wei, G.L.2    Xiao, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.