In vivo effects of Panax ginseng extracts on the cytochrome P450-dependent monooxygenase system in the liver of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed guinea pig

Life Sciences

Volumn 71, Issue 7, 2002, Pages 759-769

  Lee, Hyung Chul ^a   Hwang, Sang Gu ^a   Lee, Young Gu ^b   Sohn, Hyung Ok ^b   Lee, Dong Wook ^b   Hwang, Seok Youn ^c   Kwak, Yi Swong ^b   Wee, Jae Joon ^b   Joo, Woo Hong ^a   Cho, Yong Kweon ^a   Moon, Ja Young ^a  

^a Changwon National University   (South Korea)

^b Korea Ginseng Corporation   (South Korea)

^c Chungbuk National University Hospital   (South Korea)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; 7 Ethoxycoumarin O deethylase; Cytochrome P450; Guinea pig; Panax ginseng

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; BENZPHETAMINE; CYTOCHROME B5; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 2B; CYTOCHROME P450 INHIBITOR; GINSENG EXTRACT; ISOENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; GINSENG; GUINEA PIG; IN VIVO STUDY; LIVER LEVEL; LIVER MICROSOME; MALE; METHYLATION; NONHUMAN; STATISTICAL SIGNIFICANCE;

7-ALKOXYCOUMARIN O-DEALKYLASE; ANIMALS; BODY WEIGHT; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; GUINEA PIGS; INJECTIONS, INTRAPERITONEAL; LIVER; MALE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDOREDUCTASES, N-DEMETHYLATING; PANAX; PLANT EXTRACTS; TETRACHLORODIBENZODIOXIN;

CAVIA; CAVIA PORCELLUS; PANAX; PANAX GINSENG; SUS SCROFA;

EID: 0037025060     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01742-3     Document Type: Article

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