An efficient and convenient synthesis of tetrahydrocycloheptapyridines: New precursors for CNS agents

Synthesis

Volumn , Issue 10, 2005, Pages 1593-1600

  Yoshizumi, Takashi ^a   Miyazoe, Hiroshi ^a   Sugimoto, Yuichi ^a   Takahashi, Hirobumi ^a   Okamoto, Osamu ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Cycloheptanone; Hydroxymethylation; Iodomethylation; Radical reaction; Ring expansion

Indexed keywords

KETONES; NITROGEN COMPOUNDS; ORGANIC COMPOUNDS; REACTION KINETICS;

CYCLOHEPTANONES; IODOMETHYLATION; RADICAL RING EXPANSION; TETRAHYDROCYCLOHEPTAPYRIDINES;

SYNTHESIS (CHEMICAL);

1,1' AZOBIS(CYCLOHEXANECARBONITRILE); 5 OXOTETRAHYDROISOQUINOLINE DERIVATIVE; 5 OXOTETRAHYDROQUINOLINE DERIVATIVE; 5,6,7,8 TETRAHYDROCYCLOHEPTAPYRIDIN 9 ONE DERIVATIVE; 6,7,8,9 TETRAHYDROCYCLOHEPTAPYRIDIN 5 ONE DERIVATIVE; 8 OXOTETRAHYDROISOQUINOLINE DERIVATIVE; 8 OXOTETRAHYDROQUINOLINE DERIVATIVE; CENTRAL NERVOUS SYSTEM AGENTS; CYCLOALKANONE; CYCLOHEPTANONE DERIVATIVE; CYCLOHEXANE DERIVATIVE; ETHYL 5 OXO 5,6,7,8 TETRAHYDROISOQUINOLINE 6 CARBOXYLATE; ETHYL 5 OXO 5,6,7,8 TETRAHYDROQUINOLINE 6 CARBOXYLATE; ETHYL 8 OXO 5,6,7,8 TETRAHYDROISOQUINOLINE 7 CARBOXYLATE; ETHYL 8 OXO 5,6,7,8 TETRAHYDROQUINOLINE 7 CARBOXYLATE; ETHYL 9 OXO 6,7,8,9 TETRAHYDRO 5H CYCLOHEPTA[B]PYRIDINE 7 CARBOXYLATE; FUNCTIONAL GROUP; HETEROCYCLIC COMPOUND; PYRIDINE DERIVATIVE; QUINOLINE DERIVATIVE; TETRAHYDROCYCLOHEPTAPYRIDINE DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE; TRIBUTYLTIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; IODOMETHYLATION; PRECURSOR; RADICAL REACTION; RADICAL RING EXPANSION; SYNTHESIS;

EID: 22244459151     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865306     Document Type: Article

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