N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 24, 1999, Pages 3411-3416

  Uckun, Fatih M ^a,b   Pendergrass, Sharon ^b   Maher, Danielle ^b   Zhu, Dan ^a   Tuel Ahlgren, Lisa ^a   Mao, Chen ^a   Venkatachalam, T K ^a,b  

^a Drug Discovery Program   (United States)

^b PARKER HUGHES INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELAVIRDINE; EMIVIRINE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; THIOUREA DERIVATIVE; TROVIRDINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; BLOOD; CHEMICAL MODIFICATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN;

EID: 0033590276     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00624-1     Document Type: Article

References (11)

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11. 13C NMR (DMSO) δ 179.8, 152.5, 151.0, 146.3, 142.7, 141.7, 114.8, 112.3, 110.8, 107.8,41.6.