Analysis of tumour-derived DNA in serum in advanced non-microcytic lung cancer: Might it be a prognostic factor?;Análisis de la concentración sérica del ADN tumoral en el cáncer de pulmón no microcítico y avanzado: ¿Es útil como factor pronóstico?

Clinical and Translational Oncology

Volumn 7, Issue 3, 2005, Pages 122-126

  Herrero, Carlos Camps ^a   Zaera, Pilar Bayo ^a   Pérez, Rafael Sirera ^a   Salvador, Eva Sancho ^a   Cordellat, Ana Blasco ^a   Aguilera, María José Safont ^a  

^a HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

Author keywords

Blood; Dna; Non microcytic lung cancer; Serum

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; BLOOD; FEMALE; GENETICS; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; MIDDLE AGED; PREDICTION AND FORECASTING; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; DNA, NEOPLASM; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS;

EID: 22244439561     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/BF02708745     Document Type: Article

References (21)

1. Wang BG, Huang HY, Chen YC, et al. Increased plasma DNA integrity in cancer patients. Cancer Res. 2003; 63: 3966-8.
2. Silva JM, Silva J, Sanchez A, et al. Tumor DNA in plasma at diagnosis of breast cancer patients is a valuable predictor of disease-free survival. Clin Cancer Res. 2002; 8: 3761-6.
3. Anker P, Stroun M. Tumor-related alterations in circulating DNA, potential for diagnosis, prognosis and detection of minimal residual disease. Leukemia. 2001; 15: 289-91.
4. Rosell R, O'Brate A, Monzo M, et al. Pharmacogenomic research and serum DNA analysis in the treatment of non-small cell lung cancer. Rev Oncología. 2001; 3: 60-71.
5. Ramírez JL, Taron M, Balana C, et al. Serum DNA as a tool for cancer patient management. Rocz Akad Med Bialymst. 2003; 48: 34-41.
6. Chen X, Bonnefoi H, Diebold-Berger S, et al. Detecting tumor-related alterations in plasma or serum DNA of patients diagnosed with breast cancer. Clin Cancer Res. 1999; 5: 2297-303.
7. Ziegler A, Zangemeister-Wittke U, Stahel RA. Circulating DNA: a new diagnostic gold mine? Cancer Treat Rev. 2002; 28: 255-71.
8. Sozzi G, Conte D, Mariani L, et al. Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res. 2001; 61: 4675-8.
9. De Kok JB, van Solinge WW, Ruers TJ, et al. Detection of tumour DNA in serum of colorectal cancer patients. Scand J Clin Lab Invest. 1997; 57: 601-4.
10. Leon SA, Shapiro B. Sklaroff DM, Yaros MJ. Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res. 1977; 37: 646-50.
11. Sozzi G, Conte D, Leon M, et al. Quantification of free circulating DNA as a diagnostic marker in lung cancer. J Clin Oncol. 2003; 21: 3902-8.
12. Silva JM, Domínguez G, García JM, et al. Presence of tumor DNA in plasma of breast cancer patients: clinico-pathological correlations. Cancer Res. 1999; 59: 3251-6.
13. Jung K, Stephan C, Lewandowski M, et al. Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer. Cancer Lett. 2004; 205: 173-80.
14. Lecomte T, Berger A, Zinzindohoue F, et al. Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis. Int J Cancer. 2002; 100: 542-8.
15. Coulet F, Blons H, Cabelguenne A, et al. Detection of plasma tumor DNA in head and neck squamous cell carcinoma by microsatellite typing and p53 mutation analysis. Cancer Res. 2000; 60: 707-11.
16. Wu TL, Zhang D, Chia JH, Tsao KH, Sun CF, Wu JT. Cell-free DNA: measurement in various carcinomas and establishment of normal reference range. Clin Chim Acta. 2002; 321: 77-87.
17. Lee TH, Montalvo L, Chrebtow V, et al Quantitation of genomic DNA in plasma and serum samples: higher concentrations of genomic DNA found in serum than in plasma. Transfusion. 2001; 41: 276-82.
18. Chiu RWK, Poon LLM, Lau TK, et al. Effects of blood-processing protocols on fetal and total DNA quantification in maternal plasma. Clin Chem. 2001; 47: 1607-13.
19. De Kok JB, Hendriks JCM, van Solinge WW, et al. Use of real-time quantitative PCR to compare DNA isolation methods. Clin Chem. 1998; 44: 2201-4.
20. Jahr S, Hentze H, Englisch S, et al. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res. 2001; 61: 1659-65.
21. Bunn PA Jr. Early detection of lung cancer using serum RNA or DNA markers: Ready for "prime time" or for Validation? J Clin Oncol. 2003; 21: 3891-3.