Early detection of lung cancer using serum RNA or DNA markers: Ready for "prime time" or for validation?

Journal of Clinical Oncology

Volumn 21, Issue 21, 2003, Pages 3891-3893

  Bunn Jr , Paul A ^a  

^a UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; RNA; TELOMERASE REVERSE TRANSCRIPTASE; TUMOR MARKER;

BREAST CANCER; CANCER DIAGNOSIS; CLINICAL FEATURE; EDITORIAL; GENE EXPRESSION; GENE MUTATION; HUMAN; LUNG CANCER; ONCOGENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; BLOOD; CASE CONTROL STUDY; GENETICS; LUNG TUMOR; NOTE; POLYMERASE CHAIN REACTION; REPRODUCIBILITY; STANDARD;

CASE-CONTROL STUDIES; DNA, NEOPLASM; HUMANS; LUNG NEOPLASMS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL;

EID: 0642373293     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2003.07.976     Document Type: Editorial

References (16)

1. Marcus PM, Bergstralh EJ, Fagerstrom RM, et al: Lung cancer mortality in the Mayo Lung Project: Impact of extended follow-up. J Natl Cancer Inst 92:1308-1316, 2000
2. Hirsch FR, Franklin WA, Gazdar AF, et al: Early dectection of lung cancer: Clinical perspectives of recent advances in biology and radiology. Clin Cancer Res 1:5-22, 2001
3. Sozzi G, Conte D, Leon M, et al: Quantification of free circulating DNA as a diagnostic marker in lung cancer. J Clin Oncol 21:3902-3908, 2003
4. Fournie GJ, Courtin JP, Laval F, et al: Plasma DNA as a marker of cancerous cell death: Investigations in patients suffering from lung cancer and in nude mice bearing human tumours. Cancer Lett 91:221-227, 1995
5. Sozzi G, Conte D, Mariani L, et al: Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res 61:4675-4678, 2001
6. Chen XQ, Bonnefoi H, Pelte MF, et al: Telomerase RNA as a detection marker in the serum of breast cancer patients. Clin Cancer Res 6(10):3823-3826, 2000
7. Kopreski MS, Benko FA, Gocke CD: Circulating RNA as a tumor marker: Detection of 5T4 mRNA in breast and lung cancer patient serum. Ann N Y Acad Sci 945:172-178, 2001
8. Usadel H, Brabender J, Danenberg KD, et al: Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer. Cancer Res 62:371-375, 2002
9. Ramirez JL, Sarries C, de Castro PL, et al: Methylation patterns and K-ras mutations in tumor and paired serum of resected non-small-cell lung cancer patients. Cancer Lett 193:207-216, 2003
10. Bearzatto A, Conte D, Frattini M, et al: p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer. Clin Cancer Res 8:3782-3787, 2002
11. Esteller M, Sanchez-Cespedes M, Rosell R, et al: Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 59:67-70, 1999
12. Sozzi G, Musso K, Ratcliffe C, et al: Detection of microsatellite alterations in plasma DNA of non-small cell lung cancer patients: A prospect for early diagnosis. Clin Cancer Res 5:2689-2692, 1999
13. Bruhn N, Beinert T, Oehm C, et al: Detection of microsatellite alterations in the DNA isolated from tumor cells and from plasma DNA of patients with lung cancer. Ann N Y Acad Sci 906:72-82, 2000
14. Cuda G, Gallelli A, Nistico A, et al: Detection of microsatellite instability and loss of heterozygosity in serum DNA of small and non-small cell lung cancer patients: A tool for early diagnosis? Lung Cancer 30:211-214, 2000
15. Chen XQ, Stroun M, Magnenat JL, et al: Microsatellite alterations in plasma DNA of small cell lung cancer patients. Nat Med 2:1033-1035, 1996
16. Gonzalez R, Silva JM, Sanchez A, et al: Microsatellite alterations and TP53 mutations in plasma DNA of small-cell lung cancer patients: Follow-up study and prognostic significance. Ann Oncol 11:1097-1104, 2000