Tumor DNA in plasma at diagnosis of breast cancer patients is a valuable predictor of disease-free survival

Clinical Cancer Research

Volumn 8, Issue 12, 2002, Pages 3761-3766

  Silva, Jose M ^a   Silva, Javier ^a   Sanchez, Antonio ^a   Garcia, Jose M ^a   Dominguez, Gemma ^a   Provencio, Mariano ^a   Sanfrutos, Luis ^b   Jareño, Eugenia ^b   Colas, Antonio ^a   España, Pilar ^a   Bonilla, Felix ^a  

^a HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^b HOSPITAL UNIVERSITARIO SANTA CRISTINA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P53; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DNA DETERMINATION; GENE MUTATION; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CASE-CONTROL STUDIES; DISEASE-FREE SURVIVAL; DNA, NEOPLASM; FEMALE; FOLLOW-UP STUDIES; GENES, P53; GENETIC MARKERS; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHATIC METASTASIS; MASTECTOMY; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 0036897543     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Greenlee, R. T., Murray, T., Bolden, S., and Wingo, P. A. Cancer statistics, 2000. CA Cancer J. Clin., 50: 7, 33, 2000.
2. Clarke, D. H., and Martinez, A. A. Identification of patients who are a high risk for locoregional breast cancer recurrence after conservative surgery and radiotherapy: A review article for surgeons, pathologists, and radiation oncologists. J. Clin. Oncol., 10: 474-483, 1992.
3. Leitch, A. M., Dodd, G. D., and Constanza, M. American Cancer Society guidelines for the early detection of breast cancer. CA Cancer J. Clin., 47: 150-153, 1997.
4. Caponigro, F. CA 15.3 in human breast cancer. Comparison with tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA). Int. J. Biol. Markers, 5: 73-76, 1990.
5. Mao, L., Hruban, R. H., Boyle, J. O., Tockman, M., and Sidransky, D. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res., 54: 1634-1637, 1994.
6. Sidransky, D., Von Eschenbach, A., Tsai, Y. C., Jones, P., Summerhayes, I., Marshall. F., Paul, M., Green, P., Hamilton, S. R., Frost, P., and Vogelstein, B. Identification of p53 gene mutations in bladder cancers and urine samples. Science (Wash. DC), 252: 706-709, 1991.
7. Kondo, H., Sugano, K., Fukamaya, N., Kyogoku, A., Nose, H., Shimada, K., Ohkura, H., Ohtsu, A., Yishida, S., and Shimosato, Y. Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma. Cancer (Phila.), 73: 1589-1594, 1994.
8. Sidransky, D., Tokino, T., Hamilton, S. R., Kinzler, K. W., Levin, B., Frost, P., and Vogelstein, B. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science (Wash. DC), 256: 102-105, 1992.
9. Toyama, T., Iwase, M., Yamashita, H., Iwata, H., Yamashita, T., Ito, K., Hara, Y., Suchi, M., Kato, T., Nakamura, T., and Kobayashi, S. Microsatellite instability in sporadic human breast cancer. Int. J. Cancer, 68: 447-451, 1996.
10. Phelan, C. M., Borg, A., Cuny, M., Crichon, C. N., Baldersson, T., Andersen, T. I., Caligo, M. A., Lidereau, R., Lindblom, A., Seitz, S., Kelsell, D., Hamann, U., Rio, P., Thorlacius, S., Papp, J., Olah, E., Ponder, B., Bignon, Y-J., Scherneck, S., Barkardottir, R., Borresen-Dale, A-L., Eyfjörd, J., Theillet, C., Thompson, A. M., Devilee, P., and Larsson, C. Consortium study on 1280 breast carcinomas: Allelic loss on chromosome 17 target subregions associated with family history and clinical parameters. Cancer Res., 58: 1004-1012, 1998.
11. Deng, G., Lu, Y., Zlotnikov, G., Thor, A. N., and Smith, H. S. Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science (Wash. DC), 274: 2057-2059, 1996.
12. Kumar, R., Sukumar, S., and Barbacid, M. Activation of ras oncogenes preceding the onset of neoplasia. Science (Wash. DC), 248: 1101-1104, 1990.
13. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. p53 mutations in human cancers. Science (Wash. DC), 253: 49-53, 1991.
14. Sjögren, S., Inganäs, M., Norberg, T. Lindgren, A., Nordgren, H., Holmberg, L., and Bergh, J. The p53 gene in breast cancer: Prognostic value of complementary DNA sequencing versus immunohistochemistry. J. Natl. Cancer Inst. (Bethesda), 88: 173-182, 1996.
15. Silva, J. M., Dominguez, G., Garcia, J. M., Gonzalez, R., Villanuea, M. J., Navarro, F., Provencio, M., San Martin, S., España, P., and Bonilla, F. Presence of tumor DNA in plasma of breast cancer patients: Clinicopathological correlations. Cancer Res., 59: 3251-3256, 1999.
16. Chen, X., Bonnefoi, H., Diebol-Berger, S., Lyautey, J., Lederrey, C., Faltin-Traub, E., Stroun, M., and Anker, P. Detecting tumor-related alterations in plasma or serum DNA of patients diagnosed with breast cancer. Clin. Cancer Res., 5: 2297-2303, 1999.
17. Mayall, F., Fairweather, S., Wilkins, R., Chang, B., and Nicolls, R. Microsatellite abnormalities in plasma of patients with breast carcinomas: Concordance with primary tumour. J. Clin. Pathol. (Lond.), 5: 363-366, 1999.
18. Shaw, J. A., Smith, B. M., Walsh, T., Johnson, S., Primrose, L., Slade, M. J., Walker, R. A., and Coombes, R. C. Microsatellite alterations plasma DNA of primary breast cancer patients. Clin. Cancer Res., 6: 1119-1124, 2000.
19. Silva, J. M., Gonzalez, R., Dominguez, G., Garcia, J. M., España, P., and Bonilla, F. TP53 gene mutations in plasma DNA of cancer patients. Genes Chromosomes Cancer, 24: 160-161, 1999.
20. 16INK4a gene in plasma DNA of breast cancer patients. Br. J. Cancer, 80: 1262-1264, 1999.
21. Castells, A., Puig, P., Mora, J., Boadas, J., Boix, L., Urgell, E., Solé, M., Capellá, G., Lluis, F., Fernandez-Cruz, L., Navarro, S., and Farré A. K-ras mutations in DNA extracted from the plasma of patients with pancreatic carcinoma: Diagnostic utility and prognostic significance. J. Clin. Oncol., 17: 578-584, 1999.
22. Kawakami, K., Brabender, J., Lord, R. V., Groshen, S., Greenwald, B. D., Krasna, M. J., Yin, J., Fleisher, S., Abraham, J. M., Beer, D. G., Sidransky, D., Huss, H. T., Demeester, T. R., Eads, C., Laird, P. W., Ilson, D. J., Kelsen, D. P., Harpole, D., Moore, M-B., Danenberg, K. D., Danenberg, K. V., and Meltzer, S. J. Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma. J. Natl. Cancer Inst. (Bethesda), 92: 1805-1811, 2000.
23. Sozzi, G., Conte, D., Mariani, L., Lo Vullo, S., Roz, L., Lombardo, C., Pierotti, M. A., and Tavecchio, L. Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients. Cancer Res., 61: 4675-4678, 2001.
24. Taback, B., Fujiwara, Y., Wang, H-J., Foshag, L. J., Morton, D. L., and Hoon, D. S. B. Prognostic significance of circulating microsatellite markers in the plasma of melanoma patients. Cancer Res., 61: 5723-5726, 2001.
25. Nawroz, H., Koch, W., Anker, P., Stroun, M., and Sidransky, D. Microsatellite alterations in serum DNA of head and neck cancer patients. Nat. Med., 2: 1035-1037, 1996.
26. Frickhofen, N., Muller, E., Sandherr, M., Binder, T., Bangerter, M., Wiest, C., Enz, M., and Heimpel, H. Rearranged Ig heavy chain DNA is detectable in cell-free blood samples of patients with B-cell neoplasia. Blood, 90: 4953-4960, 1997.
27. Goldhirsch, A., Wood, W. C., Senn, H-J., Glick, J. H., and Gelber, R. D. Meeting highlights: International consensus panel on the treatment of primary breast cancer. J. Natl. Cancer Inst. (Bethesda), 87: 1441-1445, 1995.
28. Anderson, L. A., Friedman, L., Osborne-Lawrence, S., Lynch, E., Weissenbach, J., Bowcock, A., and King. M-C. High-density genetic map of the BRCA1 region of chromosome 17q12-q21. Genomics, 17: 618-623, 1993.
29. Steiner, G., Schoenberg, M. P., Linn, J. F., Mao, L., and Sidransky, D. Detection of bladder cancer recurrence by microsatellite analysis of urine. Nat. Med., 3: 621-624, 1997.
30. Skirnisdottir, S., Eiriksdottir, G., Baldursson, T., Barkardottir, R. B., Egilsson, V., and Ingvarsson, S. High frequency of allelic imbalance at chromosome region 16q22-23 in human breast cancer: Correlation with high PgR and low S phase. Int. J. Cancer, 64: 112-116, 1995.
31. Patel, U., Grundfest-Broniatowski, S., Gupta, M., and Banerjee, S. Microsatellite instabilities at five chromosomes in primary breast tumors. Oncogene, 9: 3695-3700, 1994.
32. Brenner, A. J., and Aldaz, C. M. Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells. Cancer Res., 55: 2892-2895, 1995.
33. Armitage, P., and Berry, G. Statistical Methods in Medical Research. Oxford: Blackwell Scientific Publications, 1987.
34. Kaplan, E. L., and Meier, P. Non-parametric estimation from incomplete observations. J. Am. Stat. Assoc., 53: 457-481, 1958.
35. Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., Mantel, N., McPherson, K., Peto, J., and Smith, P. G. Design and analysis of randomized clinical trials requiring prolonged observations of each patient. II. Analysis and examples. Br. J. Cancer. 35: 1-39, 1977.
36. Cox, D. R. Regression models and life tables. J. Stat. Soc., 34: 187-220, 1972.
37. Chen, X. Q., Stroun, M., Magnenat, J. L., Nicod, N. P., Kurt, A-M., Lyautey, J., Lederrey, C., and Anker, P. Microsatellite alterations in plasma DNA of small cell lung cancer patients. Nat. Med., 2: 1033-1035, 1996.
38. Bates, C. Clinical applications of serum tumor markers. Ann. Intern. Med., 115: 623-638, 1991.
39. Gonzalez, R., Silva, J. M., Sanchez, A., Dominguez, G., Garcia, J. M., Chen, X., Stroun, M., Provencio, M., España, P., Anker, P., and Bonilla, F. Microsatellite alterations and TP53 mutations in plasma DNA of small-cell lung cancer patients: Follow-up study and prognostic significance. Ann. Oncol., 11: 1097-1104, 2000.
40. Veronesi, U., Goldhirsch, A., and Yarnold, J. Breast cancer. In: M. Peckham, H. M. Pinedo, and U. Veronesi (eds.), Oxford Textbook of Oncology, Vol. 2, pp. 1243-1289. Oxford: Oxford University Press, 1995.