Transcriptional Regulation and Renal Localization of 1,25-Dihydroxyvitamin D3-24-Hydroxylase Gene Expression: Effects of the Hyp Mutation and 1,25-Dihydroxyvitamin D3

Endocrinology

Volumn 137, Issue 7, 1996, Pages 2938-2946

  Roy, Stéphane ^a   Tenenhouse, Harriet S ^a,b  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; DACTINOMYCIN; OXYGENASE;

ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; GENE EXPRESSION REGULATION; GENE MUTATION; KIDNEY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION; VITAMIN D METABOLISM;

ANIMALS; ANTISENSE ELEMENTS (GENETICS); BASE SEQUENCE; CALCITRIOL; CELL NUCLEUS; CYTOCHROME P-450 ENZYME SYSTEM; DACTINOMYCIN; DUODENUM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPOPHOSPHATEMIA; KIDNEY; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; PHOSPHORUS, DIETARY; REFERENCE VALUES; RNA PROBES; STEROID HYDROXYLASES; TRANSCRIPTION, GENETIC; X CHROMOSOME;

EID: 0029897627     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.7.8770917     Document Type: Article

References (35)

1. Eicher EM, Southard JL, Scriver CR, Glorieux FH 1976 Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets. Proc Natl Acad Sci USA 73:4667-4671
2. Tenenhouse HS, Scriver CR 1992 X-linked hypophosphatemia. A phenotype in search of a cause. Int J Biochem 24:685-691
3. Rasmussen H, Tenenhouse HS 1995 Mendelian Hypophosphatemias. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The Metabolic and Molecular Basis of Inherited Disease, ed 7. McGraw-Hill, New York, pp 3717-3745
4. Meyer Jr RA, Gray RW, Meyer MH 1980 Abnormal vitamin D metabolism in the X-linked hypophosphatemic mouse. Endocrinology 107:1577-1581
5. Tenenhouse HS, Jones G 1990 Abnormal regulation of renal vitamin D catabolism by dietary phosphate in murine X-linked hypophosphatemic rickets. J Clin Invest 85:1450-1455
6. 3-1-hydroxylase activity in the vitamin D and calcium deficient X-linked Hyp mouse. Endocrinology 113:816-818
7. 3 in renal slices from the X-linked hypophosphatemic (Hyp) mouse: abnormal response to fall in serum calcium. Cell Calcium 5:43-55
8. Nesbitt T, Drezner MK, Lobaugh B 1986 Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D-1α-hydroxylase activity in the hypophosphatemic mouse: evidence for a generalized defect of vitamin D metabolism. J Clin Invest 77:181-187
9. Yamaoka K, Seino Y, Satomura K, Tanaka Y, Yabuuchi H, Haussler MR 1986 Abnormal relationship between serum phosphate concentration and renal 25-hydroxycholecalciferol-l-alpha-hydroxylase activity in X-linked hypophosphatemic mice. Miner Electrolyte Metab 12:194-198
10. Nesbitt T, Davidai GA, Drezner MK 1989 Abnormal adenosine 3′,5′-mophosphate stimulation of renal 1,25-dihydroxyvitamin D production in Hyp mice: evidence that 25-hydroxvvitamin D-1 α-hydroxylase dysfunction results from aberrant intracellular function. Endocrinology 124:1184-1189
11. Nesbitt T, Drezner MK 1990 Abnormal parathyroid hormone-related peptide stimulation of renal 25-hydroxyvitamin D-1-hydroxylase in Hyp mice: evidence for a generalized defect of enzyme activity in the proximal convoluted tubule. Endocrinology 127:843-848
12. 3 treatment. Biochem Cell Biol 65:853-859
13. 3 in murine X-linked hypophosphatemic rickets. J Clin Invest 81:461-465
14. 3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation. Biochem J 262:173-180
15. 3 through C-24 oxidation pathway. Biochemistry 28:1763-1769
16. 3 catabolism in X-linked hypophosphatemic rickets. Endocrinology 134:1761-1767
17. 3 24-hydroxylase gene. J Biol Chem 269:10545-10550
18. 3) 24-hydroxylase gene. Proc Natl Acad Sci USA 91:900-902
19. 24 gene. Nucleic Acids Res 22:2410-2416
20. 3 24-hydroxylase. FEBS Lett 278:195-198
21. Marzluff WF, Huang RCC 1985 Transcription of RNA in isolated nuclei. In: Hames BD, Higgins SJ (eds) Transcription and Translation: A Practical Approach. IRL Press, Oxford, pp 89-129
22. 3 and its physiological implications. Steroids 49:29-53
23. 3-24-hydroxylase. J Bone Miner Res 10:1951-1959
24. Armbrecht HJ, Boltz MA 1991 Expression of 25-hydroxyvitamin D 24-hydroxylase cytochrome P450 in kidney and intestine. FEBS Lett 292:17-20
25. 3 in rat kidney but not in intestine. J Biol Chem 267:13757-13762
26. 3 24-hydroxylase): implications for differing mechanisms of regulation and involvement of multiple factors. Endocrinology 136:3971-3982
27. Ohno S 1973 Ancient linkage groups and frozen accidents. Nature 244:259-262
28. Hahn CN, Baker E, Laslo P, May BK, Omdahl JL, Sutherland GR 1993 Localization of the human vitamin-D 24-hydroxylase gene (CYP24) to chromosome-20q13.2->q13.3. Cytogenet Cell Genet 62: 192-193
29. 450 subunit maps to a different chromosomal location than that of pseudovitamin D-deficient rickets. J Bone Miner Res 8:1397-1406
30. The HYP Consortium 1995 A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nature Genet 11:130-136
31. 3 1α-hydroxylase and 24-hydroxylase along the rat nephron. Proc Natl Acad Sci USA 78:1199-1203
32. 3-24-hydroxylase mRNA expression along rat nephron segments. Biochem Biophys Res Commun 194:659-664
33. 3 24-hydroxylase in rat kidney. J Histochem Cytochem 43:255-262
34. 28k in human kidney. Am J Physiol 266: F477-F485
35. 3 in cultured skin fibroblasts. J Clin Invest 75:954-960