Trefoil factor family (TFF) peptides of normal human Vater's ampulla

Cell and Tissue Research

Volumn 321, Issue 1, 2005, Pages 67-74

  Paulsen, Friedrich ^a   Varoga, Deike ^b   Paulsen, Andreas ^c   Tsokos, Michael ^c  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Hepatopancreatic ampulla; Human; Major duodenal papilla; Mucin; Trefoil family peptides

Indexed keywords

TREFOIL PEPTIDE;

ARTICLE; AUTOPSY; BRUNNER GLAND; CARCINOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DUODENUM MUCOSA; GOBLET CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NORMAL HUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VATER PAPILLA; WESTERN BLOTTING;

ADULT; AGED; AMPULLA OF VATER; BLOTTING, WESTERN; BRUNNER GLANDS; DUODENUM; FEMALE; GOBLET CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PEPTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEINS;

LOTUS;

EID: 22144436918     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-005-1131-7     Document Type: Article

References (64)

1. Albores-Saavedra J, Henson DE, Klimstra DS (2000) Tumors of the gallbladder, extrahepatic bile ducts, and ampulla of Vater. In: Rosai J, Sobin L (eds) Atlas of tumor pathology. Third series, fascicle 27. Armed Forces Institute of Pathology, Washington DC, pp 259-316
2. Babyatsky MW, Beaumont M de, Thim L, Podolsky DK (1996) Oral trefoil peptides protect against ethanol and indomethacin-induced gastric injury in rats. Gastroenterology 110:489-497
3. Becker V (1973) Bauchspeicheldrüse (Inselapparat ausgenommen). In: Doerr W, Seifert G, Uehlinger E (eds) Spezielle pathologische Anatomie, Bd 6. Springer, Berlin Heidelberg New York, pp 38-52
4. Bossenmeyer-Pourie C, Kannan R, Ribieras S, Wndling C, Stoll I, Thim L, Tomasetto C, Rio MC (2002) The trefoil factor 1 participates in gastrointestinal cell differentiation by delaying G1-S phase transition and reducing apoptosis. J Cell Biol 147:761-770
5. Chen YH, Lu Y, De Plaen IG, Wang LY, Tan XD (2000) Transcription factor NF-kB signals antianoikic function of trefoil factor 3 on intestinal epithelial cells. Biochem Biophys Res Commun 274:576-582
6. Chwieralski CE, Schnurra I, Thim L, Hoffmann W (2004) Epidermal growth factor and trefoil factor family 2 synergistically trigger chemotaxis on BEAS-2B cells via different signaling cascades. Am J Respir Cell Mol Biol 31:528-537
7. Ciacci C, Di Vizio D, Seth R, Insabato G, Mazzacca G, Podolsky DK, Mahida YR (2002) Selective reduction of intestinal trefoil factor in untreated coeliac disease. Clin Exp Immunol 130:526-531
8. Dignass A, Lynch-Devaney K, Kindon H, Thim L, Podolsky DK (1994) Trefoil peptides promote epithelial migration though a transforming growth factor β-independent pathway. J Clin Invest 94:376-383
9. Ebert MPA, Hoffmann J, Haeckel C, Rutkowski K, Schmid RM, Wagner M, Adler G, Schulz HU, Roessner A, Hoffmann W, Malfertheiner P (1999) Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor α. Gut 45:105-111
10. Emami S, Le Floch N, Bruyneel E, Thim L, May F, Westley B, Rio M, Mareel M, Gespach C (2001) Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells. FASEB J 15:351-361
11. Emami S, Rodrigues S, Rodrigue CM, Le Floch N, Rivat C, Attoub S, Bruyneel E, Gespach C (2004) Trefoil factro family (TFF) peptides and cancer progression. Peptides 25:885-890
12. Fischer HP, Zhou H (2003) Pathogenese und Histopathologie von Adenomen und Karzinomen der Papilla vateri. Pathologe 24:196-203
13. FitzGerald AJ, Pu M, Marchbank T, Westley BR, May FE, Boyle J, Yadollahi-Farsani M, Ghosh S, Playford RJ (2004) Synergistic effects of systemic trefoil factor family 1 (TFF1) peptide and epidermal growth factor in a rat model of colitis. Peptides 25:793-801
14. Födisch HJ (1972) Feingewebliche Studien zur Orthologie und Pathologie der Papilla vateri. Thieme, Stuttgart
15. Giermann H, Holle G (1981) Stereoskopische und histologische Untersuchungen zur Pathologie des Schleimhautreliefs und Klappenapparates der Papilla vateri. Acta Hepato-Splenol 8:189-196
16. Göke MN, Cook JR, Kunert KS, Fini ME, Gipson IK, Podolsky DK (2001) Trefoil peptides promote restitution of wounded corneal epithelial cells. Exp Cell Res 264:337-344
17. Gürbüz Y, Klöppel G (2004) Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas. Virchows Arch 444:536-541
18. Hanby AM, Poulsom R, Singh S, Elia G, Jeffery RE, Wright NA (1993a) Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides, human spasmolytic polypeptide and pS2 in the stomach. Gastroenterology 105:1110-1116
19. Hanby AM, Poulsom R, Elia G, Singh S, Longcroft JM, Wright NA (1993b) The expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in "gastric metaplasia" of the proximal duodenum: implications for the nature of "gastric metaplasia". J Pathol 169:355-360
20. Hauser F, Poulsom R, Chinery R, Rogers LA, Hanby AM, Wright NA, Hoffmann W (1993) hP1.B, a human p-domain peptide homologous with rat intestinal trefoil factor. Proc Natl Acad Sci USA 90:6961-6965
21. Hoffmann W, Jagla W (2002) Cell type specific expression of secretory TFF-peptides: colocalization with mucins and synthesis in the brain. Int Rev Cytol 213:147-181
22. Hoffmann W, Jagla W, Wiede A (2001) Molecular medicine of TFF peptides: from gut to brain. Histol Histopathol 16:319-334
23. Holle G (1960) Die Bauprinzipien der Vaterschen Papille und ihre funktionelle Bedeutung unter normalen und krankhaften Bedingungen. Dtsch Med Wochenschr 85:648-655
24. Ishibashi Y, Murakami G, Honma T, Sato TJ, Takahashi M (2000) Morphometric study of the sphincter of Oddi (hepatopancreatic) and configuration of the submucosal portion of the sphincteric muscle mass. Clin Anat 13:159-167
25. Jagla W, Wiede A, Dietzmann K, Rutkowski K, Hoffmann W (1998) Differential expression of the TFF peptides xP1 and xP4 in the gastrointestinal tract of Xenopus laevis. Cell Tissue Res 291:13-18
26. Jagla W, Wiede A, Hinz M, Dietzmann K, Gulicher D, Gerlach KL, Hoffmann W (1999) Secretion of TFF-peptides by human salivary glands. Cell Tissue Res 298:161-166
27. Khan ZE, Wang TC, Cui G, Chi AL, Dimaline R (2003) Transcriptional regulation of the human trefoil factor, TFF1, by gastrin. Gastroenterology 125:510-521
28. Khulusi S, Hanby AM, Marrero JM, Patel P, Mendall MA, Badve S, Poulsom R, Elia G, Wright NA, Northfield TC (1995) Expression of trefoil peptides pS2 and human spasmolytic polypeptide in gastric metaplasia at the margin of duodenal ulcers. Gut 37:205-209
29. Kinoshita T, Taupin DR, Itoh H, Podolsky DK (2000) Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor. Mol Cell Biol 20:4680-4690
30. Kouznetsova I, Peitz U, Vieth M, Meyer F, Vestergaard EM, Malfertheiner P, Roessner A, Lippert H, Hoffmann W (2004) A gradient of TFF3 (trefoil factor family 3) peptide synthesis within the normal human gastric mucosa. Cell Tissue Res 316:155-165
31. Kunath U, Hommering H (1981) Is the duodenal papilla an autonomic sphincter? A contribution to the functional morphology. Res Exp Med 178:103-116
32. Kutta H, Steven P, Varoga D, Paulsen F (2004) TFF peptides in the human false vocal folds of the larynx. Peptides 25:811-818
33. Lefebvre O, Wolf C, Kédinger M, Chenard MP, Tomasetto C, Chambon P, Rio MC (1993) The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression. J Cell Biol 122:191-198
34. Longman RJ, Douthwaite J, Sylvester PA, Poulsom R, Corfield AP, Thomas MG, Wright NA (2000) Coordinated localization of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut 47:792-800
35. May FEB, Semple JI, Newton JL, Westley B (2000) The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach. Gut 46:454-459
36. McKenzie C, Thim L, Parsons ME (2000) Topical and intravenous administration of trefoil factors protect the gastric mucosa from ethanol-induced injury in the rat. Aliment Pharmacol Ther 14:1033-1040
37. Oddi R (1887) D'une disposition á sphincter spécial de l'ouverture du canal choledoque. Arch Ital Biol 8:317-322
38. Oertel M, Graneß A, Thim L, Buhling F, Kalbacher H, Hoffmann W (2001) Trefoil factor family-peptides promote migration of human bronchial epithelial cells: synergistic effect with epidermal growth factor. Am J Respir Cell Mol Biol 25:418-424
39. Ohshio G, Suwa H, Kawaguchi Y, Imamura M, Yamaoka Y, Yamabe H, Matsumoto M, Yoshioka H, Hashimoto Y, Takeda H (2000) Differential expression of human spasmolytic polypeptide (trefoil factor family-2) in pancreatic carcinomas, ampullary carcinomas, and mucin-producing tumors of the pancreas. Dig Dis Sci 45:659-664
40. Paulsen F, Bobka T, Tsokos M, Fölsch UR, Tillmann B (2002a) Functional anatomy of the papilla Vateri: biomechanical aspects and impact of papillotomy. Surg Endosc 16:296-301
41. Paulsen FP, Hinz M, Schaudig U, Thale AB, Hoffmann W (2002b) TFF peptides in the human efferent tear ducts. Invest Ophthalmol Vis Sci 43:3359-3364
42. Paulsen F, Jansen A, Varoga D, Podolsky D, Barker N, Woon CW (2004) TFF-peptides promote restitution of wounded cornea. Ann Anat Suppl 186:69-70
43. Playford RJ, Ghosh S, Mahmood A (2004) Growth factors and trefoil peptides in gastrointestinal health and disease. Curr Opin Pharmacol 4:567-571
44. Podolsky DK, Lynch-Devaney K, Stow JL, Oates P, Murgue B, De-Beaumont M, Sands BE, Mahida YR (1993) Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion. J Biol Chem 268:6694-6702
45. Rio MC, Bellocq JP, Daniel JY, Tomasetto C, Lathe R, Chenard MP, Batzenschlager A, Chambon P (1988) Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science 241:705-708
46. Rio MC, Chenard MP, Wolf C, Marcellin L, Tomasetto C, Lathe R, Bellocq JP, Chambon P (1991) Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. Gastroenterology 100:375-379
47. Santos Silva E dos, Ulrich M, Doring G, Botzenhart K, Gott P (2000) Trefoil factor family domain peptides in the human respiratory tract. J Pathol 190:133-142
48. Sasaki M, Ikeda H, Ohira S, Ishikawa A, Nakanuma Y (2004) Expression of trefoil factor family 1, 2, and 3 peptide is augmented in hepatolithiasis. Peptides 25:763-770
49. Srivatsa G, Giraud AS, Ulaganathan M, Yeomans ND, Dow C, Nicoll AJ (2002) Biliary epithelial trefoil peptide expression is increased in biliary diseases. Histopathology 40:261-268
50. Steven P, Schäfer G, Nölle B, Hinz M, Hoffmann W, Paulsen F (2004) Distribution of TFF peptides in corneal disease and pterygium. Peptides 25:819-825
51. Sun FJ, Kaur S, Ziemer D, Banerjee S, Samuelson LC, De Lisle RC (2003) Decreased gastric bacterial killing and up-regulation of protective genes in small intestine in gastrin-deficient mouse. Dig Dis Sci 48:976-985
52. Taupin DR, Kinoshita K, Podolsky DK (2000) Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci USA 97:799-804
53. Terris B, Blaveri E, Crnogorac-Jurcevic T, Jones M, Missiaglia E, Ruszniewski P, Sauvanet A, Lemoine NR (2002) Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas. Am J Pathol 160:1745-1754
54. Thim L, Madsen F, Poulsen SS (2002) Effect of trefoil factors on the viscoelastic properties of mucus gels. Eur J Clin Investig 32:519-527
55. Tomasetto C, Rio MC, Gautier C, Wolf C, Hareuveni M, Chambon P, Lathe R (1990) hSP, the human homolog of pS2 protein is co-expressed with pS2 in stomach but not in breast carcinoma. EMBO J 9:407-414
56. Tomasetto C, Masson R, Linaires J-L, Wendling C, Lefebvre O, Chenard MP, Rio MC (2000) pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins. Gastroenterology 118:70-80
57. Torres LF, Karam SM, Wendling C, Chenard MP, Kershenobich D, Tomasetto C, Rio MC (2002) Trefoil factor 1 (TFF1/pS2) deficiency activates the unfolded protein response. Mol Med 8:273-282
58. Van De Bovenkamp JH, Korteland-Van Male AM, Buller HA, Einerhand AW, Dekker J (2003) Metaplasia of the duodenum shows a Helicobacter pylori-correlated differentiation into gastric-type protein expression. Hum Pathol 34:156-165
59. Vater A (1748) Novum bilis diverticulum. Hallers Disputationum Anatomicum Selectarum. Gottingae 3:259-273
60. Wiede A, Hinz M, Canzler E, Torres LF, Karam SM, Wendling C, Chenard MP, Kershenobich D, Tomasetto C, Rio MC (2001) Synthesis and localization of the mucin-associated TFF peptides in the human uterus. Cell Tissue Res 303:109-115
61. Williams R, Stamp GW, Gilbert C, Pignatelli M, Lalani EN (1996) pS2 transfection of murine adenocarcinoma cell-line (410.4) enhances dispersed growth pattern in 3-D collagen gel. J Cell Sci 109:63-71
62. Wright N (1998) Aspects of the biology of regeneration and repair in the human gastrointestinal tract. Philos Trans R Soc Lond Biol 353:925-933
63. Wright NA, Poulsom R, Stamp GW, Hall PA, Jeffery RE, Longcroft JM, Rio MC, Tomasetto C, Chambon P (1990) Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues. J Pathol 162:279-284
64. Zhou H, Schaefer N, Wolff M, Fischer HP (2004) Carcinoma of the ampulla of Vater. Am J Surg Pathol 28:875-882