Evaluation of protective effect of DNA vaccination with genes encoding antigens GRA4 and SAG1 associated with GM-CSF plasmid, against acute, chronical and congenital toxoplasmosis in mice

Vaccine

Volumn 23, Issue 36, 2005, Pages 4489-4499

  Mévélec, Marie Noëlle ^a   Bout, Daniel ^a   Desolme, Benoît ^a   Marchand, Hervé ^a   Magné, Rémy ^a   Bruneel, Odile ^a   Buzoni Gatel, Dominique ^b  

^a UNIVERSITÉ DE TOURS   (France)

^b INSTITUT PASTEUR   (France)

Author keywords

DNA vaccine; GRA4; SAG1; Toxoplasma gondii

Indexed keywords

GRA4 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; SAG1 ANTIGEN; SAG1 ANTIGEN PLUS GRA4 ANTIGEN PLUS GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TOXOPLASMA GONDII VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN COS7; CELLULAR IMMUNITY; CONGENITAL TOXOPLASMOSIS; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; MOUSE; NONHUMAN; OUTBRED STRAIN; PARASITE TRANSMISSION; PREGNANCY; PRIORITY JOURNAL; SURVIVAL; TH1 CELL; TOXOPLASMA GONDII; TOXOPLASMOSIS; VACCINATION; VERTICAL TRANSMISSION;

ANIMALS; ANTIGENS, PROTOZOAN; BODY WEIGHT; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; PLASMIDS; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; TOXOPLASMOSIS, CONGENITAL; VACCINATION; VACCINES, DNA;

EID: 22044439728     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.04.025     Document Type: Article

References (42)

1. D. Buxton, K. Thomson, S. Maley, S. Wright, and H.J. Bos Vaccination of sheep with a live incomplete strain (S48) of Toxoplasma gondii and their immunity to challenge when pregnant Vet Rec 129 5 1991 89 93
2. I.A. Khan, K.H. Ely, and L.H. Kasper A purified parasite antigen (P30) mediates CD8+ Tcells immunity against fatal Toxoplasma gondii infection in mice J Immunol 147 1991 3501 3506
3. N. Debard, D. Buzoni-Gatel, and D. Bout Intranasal immunization with SAG1 protein of Toxoplasma gondii in association with cholera toxin dramatically reduces development of cerebral cysts after oral infection Infect Immun 64 6 1996 2158 2166
4. F. Darcy, P. Maes, H. Grass-Masse, C. Auriault, M. Bossus, and D. Deslee Protection of mice and nude rats against toxoplasmosis by a multiple antigenic peptide construction derived from Toxoplasma gondii P30 antigen J Immunol 14 1992 3636 3641
5. V. Letscher-Bru, O. Villard, B. Risse, M. Zauke, J.-P. Klein, and T.T. Kein Protective effect of vaccination with a combination of recombinant surface antigen 1 and interleukine-12 against toxoplasmosis in mice Infect Immun 66 1998 4503 4506
6. E. Petersen, H.V. Nielsen, L. Christiansen, and J. Spenter Immunization with E. coli produced recombinant T. gondii SAG1 with alum as adjuvant protect mice against lethal infection with Toxoplasma gondii Vaccine 16 1998 1283 1289
7. V. Letscher-Bru, A.W. Pfaff, A. Abou-Bacar, D. Filisetti, E. Antoni, and O. Villard Vaccination with Toxoplasma gondii SAG-1 protein is protective against congenital toxoplasmosis in BALB/c mice but not in CBA/J mice Infect Immun 71 11 2003 6615 6619
8. T.M. Pertmer, T.R. Roberts, and J.R. Haynes Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery J Virol 70 1996 6119 6125
9. H.V. Nielsen, S.L. Lauemoller, L. Christiansen, S. Buus, A. Fomsgaard, and E. Petersen Complete protection against lethal Toxoplasma gondii infection in mice immunized with a plasmid encoding the SAG1 gene Infect Immun 67 12 1999 6358 6363
10. C.W. Angus, D. Klivington-Evans, J.P. Dubey, and J.A. Kovacs Immunization with a DNA plasmid encoding the SAG1 (P30) protein of Toxoplasma gondii is immunogenic and protective in rodents J Infect Dis 181 1 2000 317 324
11. K.N. Couper, H.V. Nielsen, E. Petersen, F. Roberts, C.W. Roberts, and J. Alexander DNA vaccination with the immunodominant tachyzoïte surface antigen (SAG-1) protects against adult acquired Toxoplasma gondii infection but does not prevent maternofoetal transmission Vaccine 21 2003 2813 2820
12. B. Desolme, M.-N. Mévélec, D. Buzoni-Gatel, and D. Bout Induction of protective immunity against toxoplasmosis in mice by DNA immunization with a plasmid encoding Toxoplasma gondii GRA4 gene Vaccine 18 23 2000 2512 2521
13. C. Ivory, and K. Chadee DNA vaccines: designing strategies against parasitic infections Genet Vaccines Ther 2 1 2004 17 25
14. M. Laugier, and M. Quilici Intérêt expérimental d'une souche de toxoplasme peu pathogene pour la souris Ann Parasitol Hum Comp 45 1970 389 403
15. D. Ajzenberg, A.L. Banuls, M. Tibayrenc, and M.L. Darde Microsatellite analysis of Toxoplasma gondii shows considerable polymorphism srtuctured into two main groups Int J Parasitol 32 1 2002 27 38
16. D. Ajzenberg, N. Cogne, L. Paris, M.H. Bessieres, P. Thulliez, and P. Filisetti Genotype of 86 Toxoplasma gondii isolates associated with human congenital toxoplasmosis, and correlation with clinical findings J Infect Dis 186 5 2002 684 689
17. J.L. Burg, D. Perelman, L.H. Kasper, P.L. Ware, and J.C. Boothroyd Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii J Immunol 141 1988 3584 3591
18. T. Chardès, I. Bourguin, M.-N. Mévélec, J.F. Dubremetz, and D. Bout Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens Infect Immun 58 5 1990 1240 1246
19. G. Couvreur, A. Sadak, B. Fortier, and J.F. Dubremetz Surface antigens of Toxoplasma gondii Parasitol 97 1988 1 10
20. H.L. Davis, R.G. Whalen, and B.A. Demeneix Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression Hum Gene Ther 4 1993 151 159
21. M.-N. Mévélec, O. Mercereau-Puijalon, D. Buzoni Gatel, I. Bourguin, T. Chardès, and J.F. Dubremetz Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by oral route Parasite Immunol 20 1998 183 195
22. S.D. Sharma, J. Mullenak, F.G. Araujo, H.A. Erlich, and J.S. Remington Western blot analysis of the antigens of Toxoplasma gondii recognized by human IgM and IgG antibodies J Immunol 131 1983 977 983
23. E.K. Pettersen Transmission of toxoplasmosis via milk from lactating mice Acta Pathol Microbiol Immunol Scand 92 3 1984 175 176
24. A.M. Tenter, A. Heckeroth, and L.M. Weiss Toxoplasma gondii: from animals to humans Int J Parasitol 30 2000 1217 1258
25. A. Fachado, A. Rodriguez, S.O. Angel, A.C. Pinta, L. Vila, and A. Acosta Protective effect of a naked DNA vaccine cocktail against lethal toxoplasmosis in mice Vaccine 21 2003 1327 1335
26. T.L. Warren, and G.J. Weiner Uses of granulocyte-macrophage colony-stimulating factor in vaccine development Curr Opin Hematol 7 2000 168 173
27. J.J. Kim, J.S. Yang, D.J. Lee, D.M. Wilson, L.K. Nottingham, and L. Morrison Macrophage colony-stimulating factor can modulate immune responses and attract dendritic cells in vivo Hum Gene Ther 11 2000 305 321
28. H. Kang, J.S. Remington, and Y. Suzuki Decreased resistance of B cell deficient mice to infection with T. gondii despite unimpaired expression of IFN-gamma, TNF-alfa and inducible nitric oxide synthasem J Immunol 164 2000 2629 2634
29. R.T. Gazzinelli, F.T. Hakim, S. Hieny, G.M. Shearer, and A. Sher Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine J Immunol 146 1991 286 292
30. Y. Suzuki, M.A. Orellana, R.D. Shreiber, and J.S. Remington Interferon-γ: the major mediator of resistance against Toxoplasma gondii Science 240 1988 516 518
31. C.W. Roberts, J.M. Brewer, and J. Alexander Congenital toxoplasmosis in the Balb/c mouse: prevention of vertical disease transmission and fetal death by vaccination Vaccine 12 15 1994 1389 1394
32. M.M.A. Elsaid, M.S. Martins, F. Frézard, E.M. Braga, and R.W.A. Vitor Vertical toxoplasmosis in a murine model. Protection after immunization with antigens of Toxoplasma gondii incorporated into liposomes Mem Inst Oswaldo Cruz 96 1 2001 99 104
33. M. Haumont, L. Delhaye, and L. Garcia Protective immunity against congenital toxoplasmosis with recombinant SAG1 protein in a guinea pig model Infect Immun 68 9 2000 4948 4953
34. B.J. Luft, and J.S. Remington Effect of pregnancy on resistance to Listeria monocytogenes and Toxoplasma gondii infections in mice Infect Immun 38 1982 1164 1171
35. T. Shirahata, N. Muroya, C. Ohta, H. Goto, and A. Nakane Correlation between increased susceptibility to primary Toxoplasma gondii infection and depressed production of gamma interferon in pregant mice Microbiol Immunol 36 1 1992 81 91
36. M. Thouvenin, E. Candolfi, O. Villard, J.P. Klein, and T. Kien Immune response in a murine model of congenital toxoplasmosis: increased susceptibility of pregnant mice and transplacental passage of Toxoplasma gondii are type 2-dependant Parasitologia 39 4 1997 279 283
37. H. Lin, T.R. Mosmann, L. Guilbert, S. Tuntipopipat, and T.G. Wegmann Synthesis of T helper 2-type cytokines at the maternal-fetal interface J Immunol 151 1993 4562
38. S. Delassus, G.C. Coutinho, C. Saucier, S. Darche, and P. Kourilsky Differential cytokine expression in maternal blood and placenta during murine gestation J Immunol 152 1994 2411
39. T. Shirahata, N. Muroya, C. Ohta, H. Goto, and A. Nakane Enhancement by recombinant human interleukin 2 of host resistance to Toxoplasma gondii infection in pregnant mice Microbiol Immunol 37 7 1993 583 590
40. A. Abou-Bacar, A.W. Pfaff, S. Georges, V. Letscher-Bru, D. Filisetti, and O. Villard Role of NK cells and gamma interferon in transplacental passage of Toxoplasma gondii in a mouse model of primary infection Infect Immun 72 3 2004 1397 1401
41. J. Alexander, H. Jebbari, H. Bluethmann, F. Brombacher, and C.W. Roberts The role of IL-4 in adult acquired and congenital toxoplasmosis Int J Parasitol 28 1998 113 120
42. M.T. Long, and T.V. Baszler Neutralization of maternal IL-4 modulates congenital protozoal transmission: comparison of innate versus acquired immune responses J Immunol 164 2000 4768 4774