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Volumn 358, Issue 1-2, 2005, Pages 60-67

Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer

Author keywords

Antioxidants; Colon cancer; Dimethylhydrazine; Ginger; Lipid peroxidation

Indexed keywords

1,2 DIMETHYLHYDRAZINE; CATALASE; GINGER EXTRACT; GLUTATHIONE PEROXIDASE; LIPID HYDROPEROXIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 22044438533     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2005.02.018     Document Type: Article
Times cited : (179)

References (56)
  • 2
    • 0034118992 scopus 로고    scopus 로고
    • Cancer statistics digest. All cancer mortality of prefectures in Japan
    • S. Yamamoto Cancer statistics digest. All cancer mortality of prefectures in Japan Jpn J Clin Oncol 30 2000 168
    • (2000) Jpn J Clin Oncol , vol.30 , pp. 168
    • Yamamoto, S.1
  • 3
    • 0016577165 scopus 로고
    • The epidemiology of large bowel cancer
    • E.L. Wynder The epidemiology of large bowel cancer Cancer Res 35 1975 3388 3394
    • (1975) Cancer Res , vol.35 , pp. 3388-3394
    • Wynder, E.L.1
  • 4
    • 0025687278 scopus 로고
    • Relation of meat, fat and fiber intake to the risk of colon cancer in a prospective study among women
    • W.C. Willett, M.J. Stamfer, G.A. Colditz, B.A. Rosner, and F.E. Speizer Relation of meat, fat and fiber intake to the risk of colon cancer in a prospective study among women N Engl J Med 323 1990 1664 1672
    • (1990) N Engl J Med , vol.323 , pp. 1664-1672
    • Willett, W.C.1    Stamfer, M.J.2    Colditz, G.A.3    Rosner, B.A.4    Speizer, F.E.5
  • 5
    • 0028891260 scopus 로고
    • Nutritional factors and colon cancer
    • B.S. Reddy Nutritional factors and colon cancer Crit Rev Food Sci Nutr 35 1995 175 190
    • (1995) Crit Rev Food Sci Nutr , vol.35 , pp. 175-190
    • Reddy, B.S.1
  • 6
    • 0019829568 scopus 로고
    • The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
    • R. Dol, and R. Peto The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today J Natl Cancer Inst 66 1987 1191 1308
    • (1987) J Natl Cancer Inst , vol.66 , pp. 1191-1308
    • Dol, R.1    Peto, R.2
  • 7
    • 0014238073 scopus 로고
    • Studies of Japanese migrants. Mortality from cancer and other diseases among Japanese in the United States
    • W. Haenszel, and M. Kurihara Studies of Japanese migrants. Mortality from cancer and other diseases among Japanese in the United States J Natl Cancer Inst 40 1968 43 68
    • (1968) J Natl Cancer Inst , vol.40 , pp. 43-68
    • Haenszel, W.1    Kurihara, M.2
  • 8
    • 0036996439 scopus 로고    scopus 로고
    • Potential role of lipid peroxidation derived DNA damage in human colon carcinogenesis: Studies on exocyclic base adducts as stable oxidative stress markers
    • H. Bartsch, and J. Nair Potential role of lipid peroxidation derived DNA damage in human colon carcinogenesis: studies on exocyclic base adducts as stable oxidative stress markers Cancer Detect Prev 26 2002 308 312
    • (2002) Cancer Detect Prev , vol.26 , pp. 308-312
    • Bartsch, H.1    Nair, J.2
  • 9
    • 0025912415 scopus 로고
    • The in vitro and in vivo effects of 1,1-dimethylhydrazine (UDMH) on murine lymphocyte subsets and Ia antigen expression
    • D.E. Frazier, M.J. Tarr, and R.G. Olsen The in vitro and in vivo effects of 1,1-dimethylhydrazine (UDMH) on murine lymphocyte subsets and Ia antigen expression Immunopharmacol Immunotoxicol 13 1991 25 46
    • (1991) Immunopharmacol Immunotoxicol , vol.13 , pp. 25-46
    • Frazier, D.E.1    Tarr, M.J.2    Olsen, R.G.3
  • 10
    • 0025903558 scopus 로고
    • Carcinogenic fungal hydrazines
    • B. Toth Carcinogenic fungal hydrazines In Vivo 5 1991 95 100
    • (1991) In Vivo , vol.5 , pp. 95-100
    • Toth, B.1
  • 11
    • 0025632980 scopus 로고
    • Carcinogenesis study in mice by 3-methylbutanal methylformylhydrazone of Gyromitra esculenta
    • B. Toth, and P. Gannett Carcinogenesis study in mice by 3-methylbutanal methylformylhydrazone of Gyromitra esculenta In Vivo 4 1990 283 288
    • (1990) In Vivo , vol.4 , pp. 283-288
    • Toth, B.1    Gannett, P.2
  • 12
    • 0017671634 scopus 로고
    • Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane
    • E.S. Fiala Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane Cancer 40 1977 2436 2445
    • (1977) Cancer , vol.40 , pp. 2436-2445
    • Fiala, E.S.1
  • 13
    • 0023554422 scopus 로고
    • Effects of chronic dietary ethanol on the in vivo and in vitro metabolism of methylazoxymethanol and methylazoxymethanol induced DNA methylation in the rat colon and liver
    • E.S. Fiala, O.S. Sohn, and S.R. Hamilton Effects of chronic dietary ethanol on the in vivo and in vitro metabolism of methylazoxymethanol and methylazoxymethanol induced DNA methylation in the rat colon and liver Cancer Res 47 1987 5939 5943
    • (1987) Cancer Res , vol.47 , pp. 5939-5943
    • Fiala, E.S.1    Sohn, O.S.2    Hamilton, S.R.3
  • 14
    • 0024472996 scopus 로고
    • Urinary excretion of N′-acetylspermidine and other acetylated and free polyamines in 1,2-dimethylhydrazine model of experimental rat colon cancer
    • A.G. Halline, P.K. Dudeja, B.A. Lashner, and T.A. Brasitas Urinary excretion of N′-acetylspermidine and other acetylated and free polyamines in 1,2-dimethylhydrazine model of experimental rat colon cancer Cancer Res 49 1989 4721 4723
    • (1989) Cancer Res , vol.49 , pp. 4721-4723
    • Halline, A.G.1    Dudeja, P.K.2    Lashner, B.A.3    Brasitas, T.A.4
  • 15
    • 0025177898 scopus 로고
    • Inhibition of carcinogenesis by naturally-occurring and synthetic compounds
    • L.W. Wattenberg Inhibition of carcinogenesis by naturally-occurring and synthetic compounds Basic Life Sci 52 1990 155 166
    • (1990) Basic Life Sci , vol.52 , pp. 155-166
    • Wattenberg, L.W.1
  • 16
    • 0025454581 scopus 로고
    • Inhibition of carcinogenesis by minor nutrient constituents of the diet
    • L.W. Wattenberg Inhibition of carcinogenesis by minor nutrient constituents of the diet Proc Nutr Soc 49 1990 173 183
    • (1990) Proc Nutr Soc , vol.49 , pp. 173-183
    • Wattenberg, L.W.1
  • 17
    • 0026229557 scopus 로고
    • Vegetables, fruits, and cancer. Epidemiology
    • K.A. Steinmetz, and J.D. Potter Vegetables, fruits, and cancer. Epidemiology Cancer Causes Control 2 1991 325 357
    • (1991) Cancer Causes Control , vol.2 , pp. 325-357
    • Steinmetz, K.A.1    Potter, J.D.2
  • 18
    • 0028242181 scopus 로고
    • Antimutagens as cancer chemopreventive agents in the diet
    • L.R. Ferguson Antimutagens as cancer chemopreventive agents in the diet Mutat Res 307 1994 395 410
    • (1994) Mutat Res , vol.307 , pp. 395-410
    • Ferguson, L.R.1
  • 19
    • 0028343701 scopus 로고
    • Antimutagens and anticarcinogens in foods
    • B. Starnic Antimutagens and anticarcinogens in foods Food Chem Toxicol 32 1994 79 90
    • (1994) Food Chem Toxicol , vol.32 , pp. 79-90
    • Starnic, B.1
  • 20
  • 21
    • 0032543420 scopus 로고    scopus 로고
    • Chemopreventive properties of some pungent ingredients present in red pepper and ginger
    • Y.J. Surh, E. Loe, and J.M. Lee Chemopreventive properties of some pungent ingredients present in red pepper and ginger Mutat Res 402 1998 259 267
    • (1998) Mutat Res , vol.402 , pp. 259-267
    • Surh, Y.J.1    Loe, E.2    Lee, J.M.3
  • 22
    • 51249161639 scopus 로고
    • Isolation and structure determination of cassumunarins A, B, C: New anti-inflammatory antioxidants from a tropical ginger, Zingible cassumunar
    • T. Masuda, A. Jitoe, and T.J. Mabry Isolation and structure determination of cassumunarins A, B, C: new anti-inflammatory antioxidants from a tropical ginger, Zingible cassumunar J Am Oil Chem Soc 72 1995 1053 1057
    • (1995) J Am Oil Chem Soc , vol.72 , pp. 1053-1057
    • Masuda, T.1    Jitoe, A.2    Mabry, T.J.3
  • 23
    • 0028118348 scopus 로고
    • Effect of dried ginger on human platelet function
    • A.B. Lumb Effect of dried ginger on human platelet function Thromb Haemost 71 1994 110 111
    • (1994) Thromb Haemost , vol.71 , pp. 110-111
    • Lumb, A.B.1
  • 24
    • 0033041930 scopus 로고    scopus 로고
    • Anti-tumor promoting activities of selected pungent phenolic substances present in ginger
    • Y.J. Surh, K.K. Park, K.S. Chun, E. Lee, and S.S. Lee Anti-tumor promoting activities of selected pungent phenolic substances present in ginger J Environ Pathol Toxicol Oncol 18 1999 131 139
    • (1999) J Environ Pathol Toxicol Oncol , vol.18 , pp. 131-139
    • Surh, Y.J.1    Park, K.K.2    Chun, K.S.3    Lee, E.4    Lee, S.S.5
  • 25
    • 0032547010 scopus 로고    scopus 로고
    • Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in IC mice
    • K.K. Park, K.S. Chu, J.M. Lee, S.S. Lee, and Y.J. Surh Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in IC mice Cancer Lett 129 1998 139 144
    • (1998) Cancer Lett , vol.129 , pp. 139-144
    • Park, K.K.1    Chu, K.S.2    Lee, J.M.3    Lee, S.S.4    Surh, Y.J.5
  • 26
    • 17844362777 scopus 로고    scopus 로고
    • [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase
    • S.O. Kim, J.K. Kundu, Y.K. Shin, J.H. Park, M.H. Cho, and T.Y. Kim [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase Oncogene 25 2005 2558 2567
    • (2005) Oncogene , vol.25 , pp. 2558-2567
    • Kim, S.O.1    Kundu, J.K.2    Shin, Y.K.3    Park, J.H.4    Cho, M.H.5    Kim, T.Y.6
  • 27
    • 0021347495 scopus 로고
    • Effects of aqueous extracts of onion, garlic acid and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system: In vitro study
    • K.C. Srivastava Effects of aqueous extracts of onion, garlic acid and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system: in vitro study Prostaglandins Leukot Med 13 1984 227 235
    • (1984) Prostaglandins Leukot Med , vol.13 , pp. 227-235
    • Srivastava, K.C.1
  • 28
    • 0026311501 scopus 로고
    • Effect of spices on cholesterol 7α-hydroxylase activities and serum and hepatic cholesterol concentrations in the rat
    • K. Srinivasan, and K. Sambaiah Effect of spices on cholesterol 7α-hydroxylase activities and serum and hepatic cholesterol concentrations in the rat Int J Vitam Nutr Res 61 1991 364 369
    • (1991) Int J Vitam Nutr Res , vol.61 , pp. 364-369
    • Srinivasan, K.1    Sambaiah, K.2
  • 29
    • 0023239754 scopus 로고
    • Lipid peroxides and human disease
    • K. Yagi Lipid peroxides and human disease Chem Phys Lipids 1978 337 351
    • (1978) Chem Phys Lipids , pp. 337-351
    • Yagi, K.1
  • 30
    • 0001360143 scopus 로고
    • The thiobarbituricacid test applied to tissues from rats treated in various ways
    • S.K. Donnan The thiobarbituricacid test applied to tissues from rats treated in various ways J Biol Chem 182 1950 415 419
    • (1950) J Biol Chem , vol.182 , pp. 415-419
    • Donnan, S.K.1
  • 31
    • 0026632930 scopus 로고
    • Detection of lipid hydroperoxides using Fox method
    • Z.Y. Jiang, J.V. Hunt, and S.P. Wolf Detection of lipid hydroperoxides using Fox method Anal Biochem 202 1992 384 389
    • (1992) Anal Biochem , vol.202 , pp. 384-389
    • Jiang, Z.Y.1    Hunt, J.V.2    Wolf, S.P.3
  • 32
    • 0014336852 scopus 로고
    • Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration
    • K.S. Rao, and R.O. Recknagel Early onset of lipid peroxidation in rat liver after carbon tetrachloride administration Exp Mol Pathol 9 1968 271 278
    • (1968) Exp Mol Pathol , vol.9 , pp. 271-278
    • Rao, K.S.1    Recknagel, R.O.2
  • 33
    • 0021681627 scopus 로고
    • A modified spectrophotometric assay of superoxide dismutase
    • P.S. Kakkar, B. Das, and P.N. Viswanathan A modified spectrophotometric assay of superoxide dismutase Indian J Biochem Biophys 21 1984 130 132
    • (1984) Indian J Biochem Biophys , vol.21 , pp. 130-132
    • Kakkar, P.S.1    Das, B.2    Viswanathan, P.N.3
  • 34
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • K.A. Sinha Colorimetric assay of catalase Anal Biochem 47 1972 389 394
    • (1972) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, K.A.1
  • 35
    • 3042934967 scopus 로고
    • Tissue sulphydryl groups
    • G.L. Ellman Tissue sulphydryl groups Arch Biochem Biophys 82 1959 72 77
    • (1959) Arch Biochem Biophys , vol.82 , pp. 72-77
    • Ellman, G.L.1
  • 37
    • 0016275313 scopus 로고
    • Glutathione-S-transferases, the first enzymatic step in mercapturic acid formation
    • W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione-S-transferases, the first enzymatic step in mercapturic acid formation J Biol Chem 249 1974 7130 7139
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 38
    • 0022272480 scopus 로고
    • Glutathione reductase
    • A. Meister Academic Press New York
    • I. Carlberg, and B. Mannervik Glutathione reductase A. Meister Methods in enzymology 1985 Academic Press New York 484
    • (1985) Methods in Enzymology , pp. 484
    • Carlberg, I.1    Mannervik, B.2
  • 39
    • 0000399955 scopus 로고
    • Detection of ascorbic acid in whole blood, and urine through the 2,4-DNPH derivative of dehydroascorbic acid
    • J.M. Roe, and C.A. Kuether Detection of ascorbic acid in whole blood, and urine through the 2,4-DNPH derivative of dehydroascorbic acid J Biol Chem 147 1943 399 407
    • (1943) J Biol Chem , vol.147 , pp. 399-407
    • Roe, J.M.1    Kuether, C.A.2
  • 40
    • 0018855509 scopus 로고
    • Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol
    • H. Baker, O. Frank, B. DeAngelis, and S. Feingold Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol Nutr Rep Int 21 1980 531 536
    • (1980) Nutr Rep Int , vol.21 , pp. 531-536
    • Baker, H.1    Frank, O.2    Deangelis, B.3    Feingold, S.4
  • 41
    • 0018815224 scopus 로고
    • Colorimetric estimation of vitamin a with trichloroacetic acid
    • R.K. Bayfield, and E.R. Cole Colorimetric estimation of vitamin A with trichloroacetic acid Methods Enzymol 67 1980 189 195
    • (1980) Methods Enzymol , vol.67 , pp. 189-195
    • Bayfield, R.K.1    Cole, E.R.2
  • 42
    • 0000470054 scopus 로고
    • Spectrophotometric studies, spectrophotometric constants for common hemoglobin derivatives in human, dog and rabbit blood
    • D.L. Drabkin, and J.M. Austin Spectrophotometric studies, spectrophotometric constants for common hemoglobin derivatives in human, dog and rabbit blood J Biol Chem 98 1932 719 733
    • (1932) J Biol Chem , vol.98 , pp. 719-733
    • Drabkin, D.L.1    Austin, J.M.2
  • 43
    • 0034199227 scopus 로고    scopus 로고
    • The effect of red beet (Beta vulgaris var. rubra) fiber on alimentary hypercholesterolemia and chemically induced colon carcinogenesis in rats
    • S. Bobek, S. Galbavy, and M. Mariassyova The effect of red beet (Beta vulgaris var. rubra) fiber on alimentary hypercholesterolemia and chemically induced colon carcinogenesis in rats Nahrung 44 2000 184 187
    • (2000) Nahrung , vol.44 , pp. 184-187
    • Bobek, S.1    Galbavy, S.2    Mariassyova, M.3
  • 44
    • 0017671634 scopus 로고
    • Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane
    • E.S. Fiala Investigations into the metabolism and mode of action of the colon carcinogen 1,2-dimethylhydrazine and azoxymethane Cancer 40 1977 2436 2445
    • (1977) Cancer , vol.40 , pp. 2436-2445
    • Fiala, E.S.1
  • 46
  • 47
    • 0026711273 scopus 로고
    • Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes
    • A.A. Reddy, and B.R. Lokesh Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes Mol Cell Biochem 111 1992 117 124
    • (1992) Mol Cell Biochem , vol.111 , pp. 117-124
    • Reddy, A.A.1    Lokesh, B.R.2
  • 48
    • 0028170326 scopus 로고
    • Importance of Se-glutathione, catalase, and Cu/Zn superoxide dismutase for cell survival against oxidative stress
    • C. Michiels, M. Raes, O. Toussaint, and J. Remach Importance of Se-glutathione, catalase, and Cu/Zn superoxide dismutase for cell survival against oxidative stress Free Radic Biol Med 17 1994 235 248
    • (1994) Free Radic Biol Med , vol.17 , pp. 235-248
    • Michiels, C.1    Raes, M.2    Toussaint, O.3    Remach, J.4
  • 49
    • 0027164510 scopus 로고
    • Cells enriched for catalase are sensitized to the toxicities of bleomycin, adriamycin and paraquat
    • M.J. Speranza, A.C. Bagley, and R.E. Lynch Cells enriched for catalase are sensitized to the toxicities of bleomycin, adriamycin and paraquat J Biol Chem 268 1993 19039 19043
    • (1993) J Biol Chem , vol.268 , pp. 19039-19043
    • Speranza, M.J.1    Bagley, A.C.2    Lynch, R.E.3
  • 50
    • 0021819571 scopus 로고
    • Plasma glutathione in health and in patients with malignant disease
    • E. Beutler, and T. Gelbart Plasma glutathione in health and in patients with malignant disease J Lab Clin Med 105 1985 581 584
    • (1985) J Lab Clin Med , vol.105 , pp. 581-584
    • Beutler, E.1    Gelbart, T.2
  • 51
    • 0025827312 scopus 로고
    • Erythrocyte defense against hydrogen peroxide, preeminent importance of catalase
    • M.D. Scott, B.H. Lubin, Linzuo, and F.A. Kuypers Erythrocyte defense against hydrogen peroxide, preeminent importance of catalase J Lab Clin Med 118 1991 7 16
    • (1991) J Lab Clin Med , vol.118 , pp. 7-16
    • Scott, M.D.1    Linzuo, H.L.B.2    Kuypers, F.A.3
  • 52
    • 0019129834 scopus 로고
    • Host tumor interactions and nutrient supply
    • G.P. Buzby, J.L. Mullen, T.P. Steih, and E.F. Roasto Host tumor interactions and nutrient supply Cancer 45 1980 2940 2947
    • (1980) Cancer , vol.45 , pp. 2940-2947
    • Buzby, G.P.1    Mullen, J.L.2    Steih, T.P.3    Roasto, E.F.4
  • 53
    • 0033014026 scopus 로고    scopus 로고
    • Antioxidant activity of ginger (Zingiber officinale R) in rats fed high fat diet
    • S.M. Jeyakumar, N. Nalini, and V.P. Menon Antioxidant activity of ginger (Zingiber officinale R) in rats fed high fat diet Med Sci Res 27 1999 341 344
    • (1999) Med Sci Res , vol.27 , pp. 341-344
    • Jeyakumar, S.M.1    Nalini, N.2    Menon, V.P.3
  • 54
    • 0030042774 scopus 로고    scopus 로고
    • Inhibition of tumor promotion in SENKAR mouse skin by ethanol extract of Zingiber officinale rhizome
    • S.K. Katiyar, R. Agarwal, and H. Mukhtar Inhibition of tumor promotion in SENKAR mouse skin by ethanol extract of Zingiber officinale rhizome Cancer Res 56 1996 1023 1030
    • (1996) Cancer Res , vol.56 , pp. 1023-1030
    • Katiyar, S.K.1    Agarwal, R.2    Mukhtar, H.3
  • 55
    • 0020074850 scopus 로고
    • Autooxidation of biological molecules: 1. the antioxidant activity of vitamin e and related chain-breaking phenolic antioxidants in vitro
    • G.W. Burton, and K.U. Ingold Autooxidation of biological molecules: 1. The antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro J Am Chem Soc 103 1981 6472
    • (1981) J Am Chem Soc , vol.103 , pp. 6472
    • Burton, G.W.1    Ingold, K.U.2
  • 56
    • 0023736564 scopus 로고
    • Vitamin C and cancer
    • A.B. Hanck Vitamin C and cancer Prog Clin Biol Res 259 1988 307 327
    • (1988) Prog Clin Biol Res , vol.259 , pp. 307-327
    • Hanck, A.B.1


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