Assessment of the eye irritating properties of chemicals by applying alternatives to the Draize rabbit eye test: The use of QSARs and in vitro tests for the classification of eye irritation

Alternatives to Laboratory Animals

Volumn 33, Issue 3, 2005, Pages 215-237

  Gerner, Ingrid ^a   Liebsch, Manfred ^a   Spielmann, Horst ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

(Q)SAR models; (Q)SAR prediction rules; Applicability domain; Draize eye test; Eye irritation corrosion potential; In vitro test; Replacement alternatives; Structural alerts

Indexed keywords

CHEMICAL AGENT;

ANIMAL TESTING ALTERNATIVE; ANIMAL TESTING REPLACEMENT; ASSAY; CLASSIFICATION; CORROSION; DRAIZE RABBIT EYE TEST; EYE INJURY; EYE IRRITATION; HAZARD ASSESSMENT; HUMAN; IN VITRO STUDY; METHODOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RABBIT; REVIEW; TOXICITY TESTING; VALIDATION PROCESS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 22044433824     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290503300307     Document Type: Review

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