Brain-derived neurotrophic factor (BDNF) in serum of patients with mania, major depression and healthy controls

Neurology Psychiatry and Brain Research

Volumn 12, Issue 1, 2005, Pages 25-28

  Laske, Christoph ^a   Stransky, Elke ^a   Eschweiler, Gerhard W ^a   Wittorf, Andreas ^a   Richartz Salzburger, Elke ^a   Bartels, Matthias ^a   Buchkremer, Gerhard ^a   Schott, Klaus ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

BDNF; HAMD; Healthy controls; Major depression; Manic episodes; Neurotrophic effects

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ARTICLE; BIPOLAR DISORDER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GROUPS BY AGE; HUMAN; MAJOR DEPRESSION; MALE; MANIA; PRIORITY JOURNAL;

EID: 21844453427     PISSN: 09419500     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Altar CA, Whitehead RE, Chen R, Wortwein G, Madsen TM. Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry 2003; 54(7):703-9
2. Angelucci F, Mathe AA, Aloe L. Neurotrophic factors and CNS disorders: findings in rodent models of depression and schizophrenia. Prog Brain Res 2004; 146:151-65
3. Angelucci F, Aloe L, Jimenez-Vasquez P, Mathe AA. Electro-convulsive stimuli alter the regional concentrations of nerve growth factor, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in adult rat brain. J ECT 2002; 18(3):138-43
4. Angelucci F, Mathe AA, Aloe L. Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration. J Neurosci Res 2000; 60(6):783-794
5. Bai O, Chlan-Fourney J, Bowen R, Keegan D, Li XM. Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. J Neurosci Res 2003; 71(1):127-31
6. Chen AC, Shin KH, Duman RS, Sanacora G. ECS-induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment. J ECT 2001; 17(1):27-32
7. Chuang DM. Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases? Crit Rev Neurobiol 2004; 16(1-2):83-90
8. Diagnostic and statistical manual of mental disorders, 4th ed.: DSM-4. Washington, D.C.: American Psychiatric Association, 1994
9. Dowlatshahi D, MacQueen G, Wang JF, Chen B, Young LT. Increased hippocampal supragranular Timm staining in subjects with bipolar disorder. Neuroreport 2000; 11:3775-8
10. Gonzalez-Pinto A, Aldama A, Pinto AG, Mosquera F, Perez de Heredia JL, Ballesteros J, Gutierrez M. Dimensions of mania: differences between mixed and pure episodes. Eur Psychiatry 2004; 19(5):307-10
11. Hairston IS, Peyron C, Denning DP, Ruby NF, Flores J, Sapolsky RM, Heller HC, O'Hara BF. Sleep deprivation effects on growth factor expression in neonatal rats: a potential role for BDNF in the mediation of delta power. J Neurophysiol 2003; 91:1586-1595
12. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
13. Henry C, Sorbara F, Lacoste J, Gindre C, Leboyer M. Anti-depressant- induced mania in bipolar patients: identification of risk factors. J Clin Psychiatry 2001; 62:249-55
14. Henry C, Swendsen J, Van den Bulke D, Sorbara F, Demotes-Mainard J, Leboyer M. Emotional hyper-reactivity as a fundamental characteristic of manic and mixed states. Eur Psychiatry 2003; 18(3):124-8
15. Hollmann W, Strüder HK, Tangarakis CVM. Körperliche Aktivität fördert Gehirngesundheit und -leistungsfähigkeit. Übersicht und eigene Befunde. Nervenheilkunde 2003; 22: 467-74
16. Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM. Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 2002; 109(2):143-148
17. Knable MB, Barci BM, Webster MJ, Meador-Woodruff J, Torrey EF. Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. Mol Psychiatry 2004; 9(6):609-20
18. Kutter P. Psychoanalytische Aspekte psychiatrischer Krankheitsbilder. In: Die Krankheitslehre der Psychoanalyse (Hrsg W Loch), p 187-286, 4. Auflage, S. Hirzel Verlag, Stuttgart, 1983
19. Lang UE, Hellweg R, Gallinat J. BDNF serum concentrations in healthy volunteers are associated with depression-related personality traits. Neuropsychopharmacology 2004; 29:795-798
20. Laske C, Stransky E, Eschweiler G, Wittorf A, Richartz-Salzburger E, Bartels M, Buchkremer G, Schott K. BDNF serum concentrations in patients with Alzheimer's disease are associated with depressive mood states. Neurology, Psychiatry and Brain Research 2005; in press
21. Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic anti-depressant treatment increases neurogenesis in adult rat hippocampus. J of Neuroscience 2000; 20(24):9104-9110
22. Molnar M, Potkin SG, Bunney WE, Jones EG. mRNA expression patterns and distribution of white matter neurons in dorsolateral prefrontal cortex of depressed patients differ from those in schizophrenia patients. Biol Psychiatry 2003; 53:39-47
23. Müller MB, Toschi N, Kresse AE, Post A, Keck ME. Longterm repetitive Transcranial Magnetic Stimulation increases the expression of Brain-derived Neurotrophic factor and Cholecystokinin mRNA, but not Neuropeptide Tyrosine mRNA in specific areas of rat brain. Neuropsychopharmacology 2000; 23:205-215
24. Nakazato M, Hashimoto K, Shimizu C, Koizumi H, Okamura N, Mitsumori M, Komatsu N, Iyo M. Decreased levels of serum brain-derived neurotrophic factor in female patients with eating disorders. Biol Psychiatry 2003; 54:485-490
25. Neves-Pereira, M., Mundo, E., Muglia, P., King, N., Macciardi, F. and Kennedy, J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet. 2002; 71:651-655.
26. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998; 37(12):1553-61
27. Pirildar S, Gonul AS, Taneli F, Akdeniz F. Low serum levels of brain-derived neurotrophic factor in patients with schizophrenia do not elevate after antipsychotic treatment. Prog Neuropsychopharmacol Biol Psychiatry 2004; 28(4):709-13
28. Poduslo JF, Curran GL. Permeability at the blood-brain barrier and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Mol Brain Res 1996; 36:280-286
29. Shimizu E, Hashimoto K, Iyo M. Major depressive disorders and BDNF (brain-derived neurotrophic factor). Nihon Shinkei Seishin Yakurigaku Zasshi 2004; 24(3):147-50
30. Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakzato M, Watanabe H, Shinoda N, Okada S, Iyo M. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003; 54:70-75
31. Shimizu E, Hashimoto K, Watanabe H, Komatsu N, Okamura N, Koike K, Shinoda N, Nakazato M, Kumakiri C, Okada S, Iyo M. Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenia are indistinguishable from controls. Neurosci Lett 2003; 351(2):111-4
32. Sklar, P., Gabriel, S.B., McInnis, M.G., Bennett, P., Lim, Y.M., Tsan, G., Schaffner, S., Kirov, G., Jones, I., Owen, M., Craddock, N., DePaulo, J.R. and Lander, E.S. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry 2002; 7:579-593.
33. Toyooka K, Asama K, Watanabe Y, Muratake T, Takahashi M, Someya T, Nawa H. Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients. Psychiatry Res 2002; 110(3):249-57
34. World Health Organization (WHO). Tenth revision of the International Classification of Diseases. Chapter 5 (F): Mental and behavioural disorders (including disorders of psychological development). Clinical Descriptions and Diagnosic Guidelines. WHO, Geneva