Stereoselective synthesis of spiroannulated cyclopentenones by the Pauson-Khand reaction on carbohydrate derived enynes

Tetrahedron Letters

Volumn 46, Issue 32, 2005, Pages 5329-5332

  Hotha, Srinivas ^a   Maurya, Sushil K ^a   Gurjar, Mukund K ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Carbohydrates; Cyclopentenone; Diversity oriented synthesis; Pauson Khand reaction

Indexed keywords

ACETALDEHYDE; ACETONITRILE; ALKYNE; CARBOHYDRATE DERIVATIVE; CARBON MONOXIDE; COBALT COMPLEX; CYCLOPENTENONE; DIMETHOXYETHANE; HEXOSE; PENTOSE; UNCLASSIFIED DRUG;

ANNULATION REACTION; ARTICLE; PAUSON KHAND REACTION; STEREOCHEMISTRY; STOICHIOMETRY; SYNTHESIS;

EID: 21844438737     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.06.013     Document Type: Article

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26. 6 complex which was then dissolved in acetonitrile (40 ml per 100 mg of complex) and dimethoxyethane (10 ml per 100 mg of complex) and kept at 85°C for 1-5 h. The reaction mixture was cooled to room temperature and then filtered through a pad of silica gel-Celite, the filtrate was concentrated in vacuo and the resulting residue was purified by silica gel column chromatography.
27. 7: C, 67.24; H, 7.67). Found: C, 67.51; H, 7.15.
28. See Supplementary data.