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Volumn 2, Issue 2, 2005, Pages 103-109

Mouse models of Down syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BEHAVIOR DISORDER; CHROMOSOME 21; COGNITIVE DEFECT; COGNITIVE THERAPY; DISEASE MODEL; DISEASE SIMULATION; DOWN SYNDROME; GENE TARGETING; HUMAN; LIFESPAN; MOUSE STRAIN; NONHUMAN; PHENOTYPE; QUALITY OF LIFE; TRANSGENIC MOUSE; TRISOMY;

EID: 21844435217     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2005.05.007     Document Type: Review
Times cited : (7)

References (40)
  • 1
    • 0037433652 scopus 로고    scopus 로고
    • Down's syndrome
    • N.J. Roizen and D. Patterson Down's syndrome Lancet 361 2003 1281-1289
    • (2003) Lancet , vol.361 , pp. 1281-1289
    • Roizen, N.J.1    Patterson, D.2
  • 3
    • 13144260659 scopus 로고    scopus 로고
    • Down syndrome and genetics - A case of linked histories
    • D. Patterson and A.C.S. Costa Down syndrome and genetics - a case of linked histories Nat. Rev. Genet. 6 2005 137-147
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 137-147
    • Patterson, D.1    Costa, A.C.S.2
  • 4
    • 0034763174 scopus 로고    scopus 로고
    • Evolutionary breakpoints on human chromosome 21
    • M.T. Davisson et al. Evolutionary breakpoints on human chromosome 21 Genomics 78 2001 99-106
    • (2001) Genomics , vol.78 , pp. 99-106
    • Davisson, M.T.1
  • 5
    • 0022871707 scopus 로고
    • Autosomal aneuploidy in mice: Generation and developmental consequences
    • J.D. Gearhart et al. Autosomal aneuploidy in mice: Generation and developmental consequences Brain Res. Bull. 16 1986 789-801
    • (1986) Brain Res. Bull. , vol.16 , pp. 789-801
    • Gearhart, J.D.1
  • 7
    • 0030732602 scopus 로고    scopus 로고
    • The embryonic development of sensory organs and the skull in the trisomy 16 mouse, an animal model for Down's syndrome
    • M. Ludwig et al. The embryonic development of sensory organs and the skull in the trisomy 16 mouse, an animal model for Down's syndrome Ann. Anat. 179 1997 525-533
    • (1997) Ann. Anat. , vol.179 , pp. 525-533
    • Ludwig, M.1
  • 8
    • 0042829429 scopus 로고    scopus 로고
    • Redox regulation of neuronal migration in a Down syndrome model
    • T.N. Behar and C.A. Colton Redox regulation of neuronal migration in a Down syndrome model Free Radic. Biol. Med. 35 2003 566-575
    • (2003) Free Radic. Biol. Med. , vol.35 , pp. 566-575
    • Behar, T.N.1    Colton, C.A.2
  • 9
    • 0032077620 scopus 로고    scopus 로고
    • Increased expression of voltage-activated calcium channels in cultured hippocampal neurons from mouse trisomy 16, a model for Down syndrome
    • Z. Galdzicki et al. Increased expression of voltage-activated calcium channels in cultured hippocampal neurons from mouse trisomy 16, a model for Down syndrome Brain Res. Mol. Brain Res. 56 1998 200-206
    • (1998) Brain Res. Mol. Brain Res. , vol.56 , pp. 200-206
    • Galdzicki, Z.1
  • 10
    • 0034734282 scopus 로고    scopus 로고
    • Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse
    • S. Peng et al. Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse Brain Res. Dev. Brain Res. 122 2000 193-197
    • (2000) Brain Res. Dev. Brain Res. , vol.122 , pp. 193-197
    • Peng, S.1
  • 11
    • 0029976912 scopus 로고    scopus 로고
    • Endocardial cushion development and heart loop architecture in the trisomy 16 mouse
    • S. Webb et al. Endocardial cushion development and heart loop architecture in the trisomy 16 mouse Dev. Dyn. 206 1996 301-309
    • (1996) Dev. Dyn. , vol.206 , pp. 301-309
    • Webb, S.1
  • 13
    • 3543110316 scopus 로고    scopus 로고
    • Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of Down syndrome
    • P. Kahlem et al. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of Down syndrome Genome Res. 14 2004 1258-1267
    • (2004) Genome Res. , vol.14 , pp. 1258-1267
    • Kahlem, P.1
  • 14
    • 0034859609 scopus 로고    scopus 로고
    • Ts65Dn - Localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome
    • E.C. Akeson et al. Ts65Dn - localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome Cytogenet. Cell Genet. 93 2001 270-276
    • (2001) Cytogenet. Cell Genet. , vol.93 , pp. 270-276
    • Akeson, E.C.1
  • 15
    • 0003043137 scopus 로고    scopus 로고
    • Down syndrome: Neuropsychology and animal models
    • L.S. Crnic and B.F. Pennington Down syndrome: Neuropsychology and animal models Prog. Infancy Res. 1 2000 69-111
    • (2000) Prog. Infancy Res. , vol.1 , pp. 69-111
    • Crnic, L.S.1    Pennington, B.F.2
  • 16
    • 0029114706 scopus 로고
    • A mouse model for Down syndrome exhibits learning and behaviour deficits
    • R.H. Reeves et al. A mouse model for Down syndrome exhibits learning and behaviour deficits Nat. Genet. 11 1995 177-184
    • (1995) Nat. Genet. , vol.11 , pp. 177-184
    • Reeves, R.H.1
  • 17
    • 0033407499 scopus 로고    scopus 로고
    • Motor dysfunction in a mouse model for Down syndrome
    • A.C. Costa et al. Motor dysfunction in a mouse model for Down syndrome Physiol. Behav. 68 1999 211-220
    • (1999) Physiol. Behav. , vol.68 , pp. 211-220
    • Costa, A.C.1
  • 18
    • 10544243361 scopus 로고    scopus 로고
    • Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
    • D.M. Holtzman et al. Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome Proc. Natl. Acad. Sci. USA 93 1996 13333-13338
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13333-13338
    • Holtzman, D.M.1
  • 19
    • 0036854588 scopus 로고    scopus 로고
    • Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome
    • A.C. Granholm et al. Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome Physiol. Behav. 77 2002 371-378
    • (2002) Physiol. Behav. , vol.77 , pp. 371-378
    • Granholm, A.C.1
  • 20
    • 0942290547 scopus 로고    scopus 로고
    • Operant conditioning in the Ts65Dn mouse: Learning
    • G.R. Wenger et al. Operant conditioning in the Ts65Dn mouse: Learning Behav. Genet. 34 2004 105-119
    • (2004) Behav. Genet. , vol.34 , pp. 105-119
    • Wenger, G.R.1
  • 21
    • 0030045921 scopus 로고    scopus 로고
    • Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: Altered behavior in the elevated plus maze and open field
    • M.E. Coussons-Read and L.S. Crnic Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: Altered behavior in the elevated plus maze and open field Behav. Genet. 26 1996 7-13
    • (1996) Behav. Genet. , vol.26 , pp. 7-13
    • Coussons-Read, M.E.1    Crnic, L.S.2
  • 22
    • 2942591228 scopus 로고    scopus 로고
    • Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
    • J.D. Cooper et al. Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion Proc. Natl. Acad. Sci. USA 98 2001 10439-10444
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10439-10444
    • Cooper, J.D.1
  • 23
    • 0037303935 scopus 로고    scopus 로고
    • Traffic at the intersection of neurotrophic factor signaling and neurodegeneration
    • A. Salehi et al. Traffic at the intersection of neurotrophic factor signaling and neurodegeneration Trends Neurosci. 26 2003 73-80
    • (2003) Trends Neurosci. , vol.26 , pp. 73-80
    • Salehi, A.1
  • 24
    • 9644278035 scopus 로고    scopus 로고
    • Synaptic structural abnormalities in the Ts65Dn mouse model of Down syndrome
    • P.V. Belichenko et al. Synaptic structural abnormalities in the Ts65Dn mouse model of Down syndrome J. Comp. Neurol. 480 2004 281-298
    • (2004) J. Comp. Neurol. , vol.480 , pp. 281-298
    • Belichenko, P.V.1
  • 25
    • 0033978891 scopus 로고    scopus 로고
    • Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse
    • L.L. Baxter et al. Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse Hum. Mol. Genet. 9 2000 195-202
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 195-202
    • Baxter, L.L.1
  • 26
    • 0033980511 scopus 로고    scopus 로고
    • Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice
    • J.T. Richtsmeier et al. Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice Dev. Dyn. 217 2000 137-145
    • (2000) Dev. Dyn. , vol.217 , pp. 137-145
    • Richtsmeier, J.T.1
  • 27
    • 0036855511 scopus 로고    scopus 로고
    • The effects of piracetam on cognitive performance in a mouse model of Down syndrome
    • T.H. Moran et al. The effects of piracetam on cognitive performance in a mouse model of Down syndrome Physiol. Behav. 77 2002 403-409
    • (2002) Physiol. Behav. , vol.77 , pp. 403-409
    • Moran, T.H.1
  • 28
    • 0032568615 scopus 로고    scopus 로고
    • Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities
    • H. Sago et al. Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities Proc. Natl. Acad. Sci. USA 95 1998 6256-6261
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6256-6261
    • Sago, H.1
  • 29
    • 0033756144 scopus 로고    scopus 로고
    • Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome
    • H. Sago et al. Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome Pediatr. Res. 48 2000 606-613
    • (2000) Pediatr. Res. , vol.48 , pp. 606-613
    • Sago, H.1
  • 30
    • 3042612213 scopus 로고    scopus 로고
    • Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
    • L.E. Olson et al. Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/ Ts65Dn exhibit variable severity of cerebellar phenotypes Dev. Dyn. 230 2004 581-589
    • (2004) Dev. Dyn. , vol.230 , pp. 581-589
    • Olson, L.E.1
  • 31
    • 0036467052 scopus 로고    scopus 로고
    • Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome
    • J.T. Richtsmeier et al. Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome Am. J. Med. Genet. 107 2002 317-324
    • (2002) Am. J. Med. Genet. , vol.107 , pp. 317-324
    • Richtsmeier, J.T.1
  • 32
    • 7444231620 scopus 로고    scopus 로고
    • A chromosome 21 critical region does not cause specific Down syndrome phenotypes
    • L.E. Olson et al. A chromosome 21 critical region does not cause specific Down syndrome phenotypes Science 306 2004 687-690
    • (2004) Science , vol.306 , pp. 687-690
    • Olson, L.E.1
  • 33
    • 0032925810 scopus 로고    scopus 로고
    • Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21
    • D. Hernandez et al. Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21 Hum. Mol. Genet. 8 1999 923-933
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 923-933
    • Hernandez, D.1
  • 34
    • 12144288763 scopus 로고    scopus 로고
    • A new mouse model for Down syndrome
    • Y. Kazuki et al. A new mouse model for Down syndrome J. Neural. Transm. Suppl. 67 2003 1-20
    • (2003) J. Neural. Transm. Suppl. , vol.67 , pp. 1-20
    • Kazuki, Y.1
  • 35
    • 0031818026 scopus 로고    scopus 로고
    • Evidence of increased oxidative stress in hippocampal primary cultures of trisomy 16 mouse. Studies on metallothionein-I/II
    • I. Hanbauer et al. Evidence of increased oxidative stress in hippocampal primary cultures of trisomy 16 mouse. Studies on metallothionein-I/II Restor. Neurol. Neurosci. 12 1998 87-93
    • (1998) Restor. Neurol. Neurosci. , vol.12 , pp. 87-93
    • Hanbauer, I.1
  • 36
    • 0034783460 scopus 로고    scopus 로고
    • Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides
    • R.C. Klein et al. Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides Neuropharmacology 2001 801-810
    • (2001) Neuropharmacology , pp. 801-810
    • Klein, R.C.1
  • 37
    • 0032729863 scopus 로고    scopus 로고
    • Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome
    • R.J. Siarey et al. Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome Neuropharmacology 38 1999 1917-1920
    • (1999) Neuropharmacology , vol.38 , pp. 1917-1920
    • Siarey, R.J.1
  • 38
    • 0032585820 scopus 로고    scopus 로고
    • Gene expression relevant to Down syndrome: Problems and approaches
    • F. Tassone et al. Gene expression relevant to Down syndrome: Problems and approaches J. Neural Transm. Suppl. 57 1999 179-195
    • (1999) J. Neural Transm. Suppl. , vol.57 , pp. 179-195
    • Tassone, F.1
  • 39
    • 0029939156 scopus 로고    scopus 로고
    • Enhanced metabolism of 1-beta-d-arabinofuranosylcytosine in Down syndrome cells: A contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia
    • J.W. Taub et al. Enhanced metabolism of 1-beta-d-arabinofuranosylcytosine in Down syndrome cells: A contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia Blood 87 1996 3395-3403
    • (1996) Blood , vol.87 , pp. 3395-3403
    • Taub, J.W.1
  • 40
    • 4644247617 scopus 로고    scopus 로고
    • Building protein interaction maps for Down syndrome
    • K. Gardiner et al. Building protein interaction maps for Down syndrome Brief. Funct. Genomics Proteomics 3 2004 142-156
    • (2004) Brief. Funct. Genomics Proteomics , vol.3 , pp. 142-156
    • Gardiner, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.