Mast cell tryptase and chymase in chronic leg ulcers: Chymase is potentially destructive to epithelium and is controlled by proteinase inhibitors

British Journal of Dermatology

Volumn 152, Issue 6, 2005, Pages 1149-1160

  Huttunen, M ^a,b   Harvima, Ilkka T ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Enzyme activity; Epithelialization; Keratinocyte; Proteinase; Wound healing

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; CALCIUM; CHYMASE; FIBRONECTIN; GROWTH FACTOR; HEPARIN; HISTAMINE; PLASTIC; PROTEINASE INHIBITOR; TRYPTASE;

ADULT; AGED; ARTICLE; CELL ADHESION; CELL CULTURE; CELL GROWTH; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; EPITHELIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; LEG ULCER; MAST CELL; MEDIATOR RELEASE; PRIORITY JOURNAL; SERUM; SKIN BIOPSY; SKIN EPITHELIUM; WOUND HEALING;

ADULT; AGED; AGED, 80 AND OVER; ALPHA 1-ANTICHYMOTRYPSIN; CALCIUM; CELL ADHESION; CELLS, CULTURED; CHRONIC DISEASE; CHYMASES; ENZYME ACTIVATION; EPITHELIUM; FEMALE; HISTAMINE; HUMANS; KERATINOCYTES; LEG ULCER; MALE; MAST CELLS; MIDDLE AGED; PROTEASE INHIBITORS; SERINE ENDOPEPTIDASES; TRYPTASES; VARICOSE ULCER; WOUND HEALING;

EID: 21644440719     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2005.06428.x     Document Type: Article

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