Amlodipine at high dose increases preproendothelin-1 expression in the ventricles and aorta of normotensive rats

Journal of Hypertension

Volumn 22, Issue 4, 2004, Pages 827-835

  Krenek, Peter ^a,b   Morel, Nicole ^a   Kyselovic, Jan ^a,b   Wibo, Maurice ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b Physics and Informatics   (Slovakia)

Author keywords

Amlodipine; Calcium channel blockers; Endothelln 1; Hypertrophy; Renin

Indexed keywords

AMLODIPINE; CARDIOTROPHIN 1; DIHYDROPYRIDINE DERIVATIVE; DRINKING WATER; INTERLEUKIN 6; MESSENGER RNA; NEUROHORMONE; NORADRENALIN; PREPROENDOTHELIN 1; RENIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG SCREENING; DRUG SENSITIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC ANALYSIS; HEART LEFT VENTRICLE; HEART RATE; HEART RIGHT VENTRICLE; HEART VENTRICLE; HORMONE ACTION; KIDNEY; MEASUREMENT; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TAIL; TIME;

EID: 2142829444     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200404000-00027     Document Type: Article

References (45)

1. Devereux RB, Palmieri V, Sharpe N, De Quattro V, Bella JN, de Simone G, et al. Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension. The Prospective Randomized Enalapril Study Evaluating Regression of Ventricular Enlargement (PRESERVE) trial. Circulation 2001; 104:1248-1254.
2. Furberg CD, Psaty BM, Meyer JV. Nifedipine: dose-related increase in mortality in patients with coronary heart disease. Circulation 1995; 92:1326-1331.
3. Psaty BM, Heckbert SR, Koepsell TD, Siscovick DF, Raghunathan TE, Weiss NS, et al. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995; 274:620-625.
4. Leenen FH, Holliwell DL. Antihypertensive effect of felodipine associated with persistent sympathetic activation and minimal regression of left ventricular hypertrophy. Am J Cardiol 1992; 69:639-645.
5. Lopez LM, Thorman AD, Mehta JL. Effects of amlodipine on blood pressure, heart rate, catecholamines, lipids and response to adrenergic stimulus. Am J Cardiol 1990; 66:1269-1271.
6. Ruzicka M, Leenen FH. Relevance of 24 h blood pressure profile and sympathetic activity for outcome on short- versus long-acting 1,4-dihydropyridines. Am J Hypertens 1995; 9:86-94.
7. Kloner RA. The issue of the cardiovascular safety of dihydropyridines. Am J Hypertens 1996; 9:182S-186S.
8. Grassi G, Seravalle G, Turri C, Bolla G, Mancia G. Short- versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension. Hypertension 2003; 41:558-562.
9. Wagner C, Krämer BK, Hinder M, Kieninger M, Kurtz A. T-type and L-type calcium channel blockers exert opposite effects on renin secretion and renin gene expression in conscious rats. Br J Pharmacol 1998; 124:579-585.
10. Schricker K, Hamann M, Macher A, Kramer BK, Kaissling B, Kurtz A. Effect of amlodipine on renin secretion and renin gene expression in rats. Br J Pharmacol 1996; 119:744-750.
11. Kyselovic J, Krenek P, Wibo M, Godfraind T. Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats. Br J Pharmacol 2001; 134:1516-1522.
12. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332:411-415.
13. Imai T, Hirata Y, Emori T, Yanagisawa M, Masaki T, Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension 1992; 19:753-757.
14. Ito H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, et al. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993; 92:398-403.
15. A-receptor antagonist. Circulation 1997; 96:1593-1597.
16. Rajagopalan S, Laursen JB, Borthayre A, Kurz S, Keiser J, Haleen S, et al. Role for endothelin-1 in angiotensin II-mediated hypertension. Hypertension 1997; 30:29-34.
17. Kaddoura S, Firth JD, Boheler KR, Sugden PH, Poole-Wilson PA. Endothelin-1 is involved in norepinephrine-induced ventricular hypertrophy in vivo. Circulation 1996; 93:2068-2079.
18. Moser L, Faulhaber J, Wiesner RJ, Ehmke H. Predominant activation of endothelin-dependent cardiac hypertrophy by norepinephrine in rat left ventricle. Am J Physiol 2002; 282:R1389-R1394.
19. Sano M, Fukuda K, Kodama H, Pan J, Saito M, Matsuzaki J, et al. Interleukin-6 family of cytokines mediate angiotensin II-induced cardiac hypertrophy in rodent cardiomyocytes. J Biol Chem 2000; 275:29717-29723.
20. Funamoto M, Hishinuma S, Fujio Y, Matsuda Y, Kunisada K, Oh H, et al. Isolation and characterization of the murine cardiotrophin-1 gene: expression and norepinephrine-induced transcriptional activation. J Mol Cell Cardiol 2000; 32:1275-1284.
21. Barth W, Deten A, Bauer M, Reinohs M, Leicht M, Zimmer HG. Differential remodeling of the left and right heart after norepinephrine treatment in rats: studies on cytokines and collagen. J Mol Cell Cardiol 2000; 32:273-284.
22. Bürger A, Benicke M, Deten A, Zimmer HG. Catecholamines stimulate interleukin-6 synthesis in rat cardiac fibroblasts. Am J Physiol Heart Circ Physiol 2001; 281:H14-H21.
23. Eickelberg O, Roth M, Mussmann R, Rudiger JJ, Tamm M, Perruchoud AP, et al. Calcium channel blockers activate the interleukin-6 gene via the transcription factors NF-IL6 and NF-κB in primary human vascular smooth muscle cells. Circulation 1999; 99:2276-2282.
24. Iwanaga Y, Kihara Y, Hasegawa K, Inagaki K, Yoneda T, Kaburagi S, et al. Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive rats. Circulation 1998; 98:2065-2073.
25. Pan J, Fukuda K, Kodama H, Sano M, Takahashi T, Makino S, et al. Involvement of gp130-mediated signaling in pressure overload-induced activation of the JAK/STAT pathway in rodent heart. Heart Vessels 1998; 13:199-208.
26. Ayoama T, Takimoto Y, Pennica D, Inoue R, Shinoda E, Hattori R, et al. Augmented expression of cardiotrophin-1 and its receptor component, gp130, in both left and right ventricles after myocardial infarction in the rat. J Mol Cell Cardiol 2000; 32:1821-1830.
27. Kobori H, Ichihara A, Miyashita Y, Hayashi M, Saruta T. Mechanism of hyperthyroidism-induced renal hypertrophy in rats. J Endocrinol 1998; 159:9-14.
28. Rodríguez-Barbero A, Martínez-Salgado C, Rodríguez-López AM, Ricote M, Sancho J, López-Novoa JM. Effect of hypothalamic-hypophysary inhibitory factor on mesangial cell activation. Hypertension 1995; 26:905-911.
29. Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, et al. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA 1995; 92:1142-1146.
30. Yamada S, Sugimoto N, Uchida S, Deguchi Y, Kimura R. Pharmacokinetics of amlodipine and its occupancy of calcium antagonist receptors. J Cardiovasc Pharmacol 1994; 23:466-472.
31. Meredith PA, Elliott HL. Clinical pharmacokinetics of amlodipine. Clin Pharmacokinet 1992; 22:22-31.
32. Lefrandt JD, Heitmann J, Sevre K, Castellano M, Hausberg M, Fallon M, et al. The effects of dihydropyridine and phenylalkylamine calcium antagonist classes on autonomic function in hypertension: the VAMPHYRE study. Am J Hypertens 2001; 14:1083-1089.
33. Uchida S, Yamada S, Nagai K, Deguchi Y, Kimura R. Brain pharmacokinetics and in vivo receptor binding of 1,4-dihydropyridine calcium channel antagonists. Life Sci 1997; 61:2083-2090.
34. Weber MA. Calcium channel antagonists in the treatment of hypertension. Am J Cardiovasc Drugs 2002; 2:415-431.
35. Hogg KJ, Hornung RS, Hillis WS, Gupta S, Grant P, Singh SP. Pharmacodynamics of amlodipine: hemodynamic effects and antianginal efficacy after atrial pacing. Am Heart J 1989; 118:1107-1113.
36. Arita M, Horinaka S, Frohlich ED. Biochemical components and myocardial performance after reversal of left ventricular hypertrophy in spontaneously hypertensive rats. J Hypertens 1993; 11:951-959.
37. Nayler WG. The effects of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. J Cardiovasc Pharmacol 1988; 12:S41-S44.
38. Morel N, Godfraind T. Selective interaction of the calcium antagonist amlodipine with calcium channels in arteries of spontaneously hypertensive rats. J Cardiovasc Pharmacol 1994; 24:524-533.
39. Yamazaki T, Komuro I, Zou Y, Kudoh S, Shiojima I, Mizuno T, et al. Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine. Hypertension 1998; 31:32-38.
40. Aristizabal D, Messerli FH, Frohlich ED. Disparate structural effects on left and right ventricles by angiotensin-converting enzyme inhibitors and calcium antagonists in essential hypertension. Am J Cardiol 1994; 73:483-487.
41. Leenen FH, Myers MG, Joyner CD, Toal CB. Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril. Can J Cardiol 2002; 18:1285-1293.
42. Stepien O, Gogusev J, Zhu DL, Louzalen L, Herembert T, Drueke TB, et al. Amlodipine inhibition of serum-, thrombin-, or fibroblast growth factor-induced vascular smooth-muscle cell proliferation. J Cardiovasc Pharmacol 1998; 31:786-793.
43. Hirata Y, Eguchi S, Tsujino M. Effects of manidipine on DNA and protein synthesis in cultured vascular smooth muscle and endothelial cells and on proto-oncogene expression. Blood Press Suppl 1992; 3:30-35.
44. Corsini A, Bonfatti M, Quarato P, Accomazzo MR, Raiteri M, Sartani A, et al. Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes. J Cardiovasc Pharmacol 1996; 28:687-694.
45. Henrion D, Laher I. Potentiation of norepinephrine-induced contractions by endothelin-1 in the rabbit aorta. Hypertension 1993; 22:78-83.