Elevated Rac1 activity changes the M3 muscarinic acetylcholine receptor-mediated inhibition of proliferation to induction of cell death

Molecular Pharmacology

Volumn 65, Issue 5, 2004, Pages 1080-1091

  Shafer, Shulamith H ^a   Williams, Carol L ^a,b  

^a GUTHRIE RESEARCH INSTITUTE   (United States)

^b Molecular Pharmacology Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; CARBACHOL; EDELFOSINE; G PROTEIN COUPLED RECEPTOR KINASE; GUANOSINE TRIPHOSPHATASE; MUSCARINIC AGENT; MUSCARINIC M3 RECEPTOR; MUTANT PROTEIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE C INHIBITOR; RAC PROTEIN; RGS PROTEIN; RHO FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; APOPTOSIS; CELL DEATH; CELL DIVISION; CHO CELLS; CRICETINAE; FEMALE; GENE EXPRESSION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; INTERCELLULAR JUNCTIONS; ISOENZYMES; PHOSPHOLIPASE C; PROTEIN KINASE C; RAC1 GTP-BINDING PROTEIN; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M3; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 2142806835     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.5.1080     Document Type: Article

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