Lesions of the Rat Nucleus Basalis Magnocellularis Disrupt Appetitive-to-Aversive Transfer Learning

Integrative Physiological and Behavioral Science

Volumn 38, Issue 4, 2003, Pages 253-271

  Butt, A E ^a   Schultz, J A ^b   Arnold, L L ^b   Garman, E E ^b   George, C L ^b   Garraghty, P E ^b  

^a CALIFORNIA STATE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 2142657777     PISSN: 1053881X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02688857     Document Type: Article

References (53)

1. Alvarado, M. C. & Rudy, J. W. (1992). Some properties of configural learning: An investigation of the transverse-patterning problem. Journal of Experimental Psychology: Animal Behavior Processes, 18, 145-153.
2. Bailey, A.M., Thomas, R.K. (2001). The effects of nucleus basalis magnocellularis lesions in Long-Evans rats on two learning set formation tasks, delayed matching-to-sample learning, and open-field activity. Behavioral Neuroscience, 115, 328-340.
3. Banks, M. K., Besheer, J., Szypczak, J., Goodpaster, L. L., Phipps, E. J., & Garraghty, P. E. (2001). The effects of carbamazepine on an appetitive-to-aversive transfer task: Comparison to untreated and phenytoin. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 25, 551-572.
4. Banks, M. K., Mohr, N. L., Besheer, J., Steinmetz, J. E., & Garraghty, P. E. (1999). The effects of phenytoin on instrumental appetitive-to-aversive transfer in rats. Pharmacology, Biochemistry and Behavior, 63, 465-472.
5. Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982). The cholinergic hypothesis of geriatric memory dysfunction. Science, 217, 408-417.
6. Baxter, M. G., Bucci, D. J., Gorman, L. K., Wiley, R. G., & Gallagher, M. (1995). Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats. Behavioral Neuroscience, 109, 714-722.
7. Baxter, M. G., Bucci, D. J., Sobel, T. J., Williams, M. J., Gorman, L. K., & Gallagher, M. (1996). Intact spatial learning following lesions of basal forebrain cholinergic neurons. Neuroreport, 7, 1417-1420.
8. Baxter, M.G., & Chiba, A.A. (1999). Cognitive functions of the basal forebrain. Current Opinions in Neurobiology, 9, 178-83.
9. Bucci, D. J., Holland, P. C., & Gallagher, M. (1998). Removal of cholinergic input to rat posterior parietal cortex disrupts incremental processing of conditioned stimuli. The Journal of Neuroscience, 18, 8038-8046.
10. Butt, A. E., & Bowman, T. D. (2002). Transverse patterning reveals a dissociation of simple and configural association learning in rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis. Neurobiology of Learning and Memory, 77, 211-233.
11. Butt, A.E., Noble, MM., Rogers, J.L., & Rea, T.E. (2002). Impairments in negative patterning but not simple discrimination learning in rats with 192 IgG-saporin lesions of the nucleus basalis magnocellularis. Behavioral Neuroscience, 116, 241-255.
12. Candy, J. M., Perry, E. K., Perry, R. H., Couet, J. A., Oakley, A. E., & Edwardson, J. A. (1986). The current status of the cortical cholinergic system in Alzheimer's disease and Parkinson's disease. Progress in Brain Research, 70, 105-132.
13. Chiba, A. A., Bucci, D. J., Holland, P. C., & Gallagher, M. (1995). Basal forebrain cholinergic lesions disrupt increments but not decrements in conditioned stimulus processing. The Journal of Neuroscience, 15, 7315-7322.
14. Coyle, J. T., Price, D. L., & DeLong, M. R. (1983). Alzheimer's disease: A disorder of cortical cholinergic innervation. Science, 219, 1184-1190.
15. Curzon, P., Bannon, A. W., & Decker, M. W. (1999). Effect of IgG-saporin injections into the nucleus basalis magnocellularis on acquisition and performance of a go/no-go procedure in the rat. Psychobiology, 27, 114-122
16. Dekker, A. J., Connor, D. J., & Thal, L. J. (1991). The role of cholinergic projections from the nucleus basalis in memory. Neuroscience & Biobehavioral Reviews, 15, 299-317.
17. Dornan, W. A., McCampbell, A. R., Tinkler, G. P., Hickman, L. J., Bannon, A. W., Decker, M. W., & Gunther, K. L. (1996). Comparison of site-specific injections into the basal forebrain on water maze and radial arm maze performance in the male rat after immunolesioning with 192 IgG saporin. Behavioral Brain Research, 82, 93-101.
18. Everitt, B. J., & Robbins, T. W. (1997). Central cholinergic systems and cognition. Annual Review of Psychology, 48, 649-684.
19. Fibiger, H. C. (1982). The organization and some projections of cholinergic neurons of the mammalian forebrain. Brain Research Review, 4, 327-388.
20. Fibiger, H. C. (1991). Cholinergic mechanisms in learning, memory and dementia: A review of recent evidence. Trends in Neuroscience, 14, 220-223.
21. Gallagher, M., & Colombo, P. J. (1995). Ageing: The cholinergic hypothesis of cognitive decline. Current Opinion in Neurobiology, 5, 161-168.
22. Grady, C. L., Grimes, A. M., Patronas, N., Sunderland, T., Foster, N. L., & Rapoport, S. I. (1989). Divided attention, as measured by dichotic speech performance, in dementia of the Alzheimer type. Archives of Neurology, 46, 317-320.
23. Heckers, S., Ohtake, T., Wiley, R. G., Lappi, D. A., Geula, C., & Mesulam, M. M. (1994). Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor. The Journal of Neuroscience, 14, 1271-1289.
24. Johannsen, P., Jakobsen, J., Bruhn, P., & Gjedde, A. (1999). Cortical responses to sustained and divided attention in Alzheimer's disease. Neuroimage, 10, 269-281.
25. Karnovsky, M. J., & Roots, L. (1964). A "direct-coloring" thiocholine method for cholinesterases. Journal of Histochemistry and Cytochemistry, 12, 219-221.
26. Kesner, R. P. (1988). Reevaluation of the contribution of the basal forebrain cholinergic system to memory. Neurobiology of Aging, 9, 609-616.
27. Mayo, W., Dubois, B., Ploska, A., Javoy-Agid, F., Agid, Y., Le Moal, M., & Simon, H. (1984). Cortical cholinergic projections from the basal forebrain of the rat, with special reference to the prefrontal cortex innervation. Neuroscience Letters, 47, 149-154.
28. McGaughy, J., Decker, M. W., & Sarter, M. (1999). Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats. Psychopharmacology, 144, 175-182.
29. McGaughy, J., Kaiser, T., & Sarter, M. (1996). Behavioral vigilance following infusions of 192 IgG-saporin into the basal forebrain: Selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density. Behavioral Neuroscience, 110, 247-265.
30. McGaughy, J., & Sarter, M. (1998). Sustained attention performance in rats with intracortical infusions of 192 IgG-saporin-induced cortical cholinergic deafferentation: Effects of physostigmine and FG 7142. Behavioral Neuroscience, 112, 1519-1525.
31. McGeer, P. L., McGeer, E. G., Suzuki, J., Dolman, C. E., & Nagia, T. (1984). Aging, Alzheimer's disease and the cholinergic system of the basal forebrain. Neurology, 34, 741-745.
32. Muir, J. L., Dunnett, S. B., Robbins, T. W., & Everitt, B. J. (1992). Attentional functions of the forebrain cholinergic systems: Effects of intraventricular hemicholinium, physostigmine, basal forebrain lesions and intracortical grafts on a multiple-choice serial reaction time task. Experimental Brain Research, 89, 611-622.
33. Olton, D. S. (1990). Dementia: Animal models of the cognitive impairments following damage to the basal forebrain cholinergic system. Brain Research Bulletin, 25, 499-502.
34. Olton, D. S., & Wenk, G. L. (1987). Dementia: Animal models of the cognitive impairments produced by degeneration of the basal forebrain cholinergic system. In H. Y. Meltzer (Ed.), Psychopharmacology: The third generation of progress (pp. 941-953). New York: Raven Press.
35. Pearce, J. M., & Hall, G. (1980). A model for Pavlovian learning: Variations in the effectiveness of conditioned but not unconditioned stimuli, Psychological Reviews, 106, 532-552.
36. Pearce, J. M., & Wilson, P. N. (1990). Configural associations in discrimination learning. Journal of Experimental Psychology: Animal Behavior Processes, 16, 250-261.
37. Ragozzino, M. E., Wilcox, C., Raso, M., & Kesner, R. P. (1999). Involvement of rodent prefrontal cortex subregions in strategy switching. Behavioral Neuroscience, 113, 32-41.
38. Rescorla, R. A. (1972). Configural conditioning in discrete-trial bar pressing. Journal of Comparative and Physiological Psychology, 79, 307-317.
39. Rescorla, R. A. (1973). Evidence for "unique stimulus" account of configural conditioning. Journal of Comparative and Physiological Psychology, 85, 331-338.
40. Rudy, J. W., & Sutherland, R. J. (1995). Configural association theory and the hippocampal formation: An appraisal and reconfiguration. Hippocampus, 5, 375-389.
41. Samuel, W., Terry, R. D., DeTeresa, R., Butters, N., & Masliah, E. (1994). Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia. Archives of Neurology, 51, 772-778.
42. Sarter, M., Bruno, J. P., & Turchi, J. (1999). Basal forebrain afferent projections modulating cortical acetylcholine, attention, and implications for neuropsychiatrie disorders. Annals of the New York Academy of Science, 877, 368-382.
43. Steinmetz, J. E., Logue, S. F., & Miller, D. P. (1993). Using signaled barpressing tasks to study the neural substrates of appetitive and aversive learning in rats: Behavioral manipulations and cerebellar lesions. Behavioral Neuroscience, 107, 941-954.
44. Sutherland, R. J., & Rudy, J. W. (1989). Configural association theory: The role of the hippocampal formation in learning, memory, and amnesia. Psychobiology, 17, 129-144.
45. Torres, E. M., Perry, T. A., Blockland, A., Wilkinson, L. S., Wiley, R. G., Lappi, D. A., & Dunnett, S. B. (1994). Behavioral, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system. Neuroscience, 63, 95-122.
46. Turchi, J., & Sarter, M. (1997). Cortical acetylcholine and processing capacity: Effects of cortical cholinergic deafferentation on crossmodal divided attention in rats. Cognitive Brain Research, 6, 147-158.
47. Waite, J. J., Wardlow, M. L., & Power, A. E. (1999). Deficit in selective and divided attention associated with cholinergic basal forebrain immunotoxic lesion produced by 192-saporin; Motoric/sensory deficit associated with purkinje cell immunotoxic lesion produced by OX7-saporin. Neurobiology of Learning and Memory, 71, 325-352.
48. Wenk, G. L. (1997). The nucleus basalis magnocellularis cholinergic system: One hundred years of progress. Neurobiology of Learning and Memory, 67, 85-95.
49. Wenk, G. L., Stoehr, J. D., Quintana, G., Mobley, S., & Wiley, R. G. (1994). Behavioral, biochemical, histological, and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats. The Journal of Neuroscience, 14, 5986-5995.
50. Whitehouse, P. J., Price, D. L., Clark, A. W., Coyle, J. T., & Delong, M. R. (1981). Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis. Annals of Neurology, 10, 122-126.
51. Wiley, R. G., Berbos, T. G., Deckworth, T., Johnson, F. M., Jr., & Lappi, D. A. (1995). Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor; Modeling the cholinergic degeneration of Alzheimer's disease. Journal of Neurological Sciences, 128, 157-166.
52. Wiley, R. G., Oeltmann, T. N., & Lappi, D. A. (1991). Immunolesioning: Selective destruction of neurons using immunotoxin to rat NGF receptor. Brain Research, 562, 149-153.
53. Wrenn, C. C., & Wiley, R. G. (1998). The behavioral functions of the cholinergic basal forebrain: Lessons from 192 IgG-saporin. International Journal of Developmental Neuroscience, 16, 595-602.