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UCB initiates clinical trials with new innovative drug compound intended for the treatment of neurological disorders
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434789 UCB Pharma SA PRESS RELEASE November 13
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434789 UCB initiates clinical trials with new innovative drug compound intended for the treatment of neurological disorders. UCB Pharma SA PRESS RELEASE 2001 November 13
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Synthesis of newer KEPPRA analogs
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463402 Synthesis of newer KEPPRA analogs. Archen L, Differding E, Evrard Y, Frycia A, Gotteaux C, Fulks B, Gillard M, Kenda B, Klitgaard H, Lallemand B, Matagne A et al DRUGS FUTURE 2002 27 Suppl A P379
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21344455405
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UCB 34714, a new pyrrolidone derivative, is effective in two models of human neuropathy in the rat: Comparison to gabapentin
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513519 Abs 586.8
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513519 UCB 34714, a new pyrrolidone derivative, is effective in two models of human neuropathy in the rat: Comparison to gabapentin. Lamberly Y, Ardid D, Eschalier A, Allow A, Segal JA, Matagne A, Kenda B, Michel P, Klitgaard HV ABSTR SOC NEUROSCI 2003 33 Abs 586.8
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UCB 34714, a new pyrrolidone derivative, reveals potent activity in in vitro and in vivo models of epilepsy
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513520 Abs 634.19
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513520 UCB 34714, a new pyrrolidone derivative, reveals potent activity in in vitro and in vivo models of epilepsy. Matagne A, Margineanu DG, Kenda B, Michel P, Klitgaard HV ABSTR SOC NEUROSCI 2003 33 Abs 634.19
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UCB 34714, a new pyrrolidone derivative, antagonizes harmaline-induced tremor in rats: Comparison to drugs for essential tremor and anti-epileptic drugs
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513521 Abs 634.20
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513521 UCB 34714, a new pyrrolidone derivative, antagonizes harmaline-induced tremor in rats: Comparison to drugs for essential tremor and anti-epileptic drugs. De Ryck M, Matagne A, Kenda B, Michel P, Klitgaard HV ABSTR SOC NEUROSCI 2003 33 Abs 634.20
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514511 Society for Neuroscience - 33rd Annual Meeting (Part XI), New Orleans, LA, USA IDDB MEETING REPORT November 8-12
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514511 Society for Neuroscience - 33rd Annual Meeting (Part XI), New Orleans, LA, USA. Taylor DP IDDB MEETING REPORT 2003 November 8-12
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UCB: Confidence in the future - Significant programmes for R&D
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517569 UCB SA PRESS RELEASE December 18
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517569 UCB: Confidence in the future - significant programmes for R&D. UCB SA PRESS RELEASE 2003 December 18
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518203 American Epilepsy Society - 57th Annual Meeting, Boston, MA, USA IDDB MEETING REPORT December 05-10
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518203 American Epilepsy Society - 57th Annual Meeting, Boston, MA, USA. Pitkanen A IDDB MEETING REPORT 2003 December 05-10
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544763 Epileptology - Sixth European Congress, Vienna, Austria IDDB MEETING REPORT May 30 - June 03
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Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity
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548202 Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity. Kenda BM, Matagne AC, Talaga PE, Pasau PM, Differding E, Lallemand BI, Frycia AM, Moureau FG, Klitgaard HV, Gillard MR, Fuks B, Michel P J MED CHEM 2004 47 3 530-549
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553128 Abs 5B
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553128 Discovery of UCB 34714 : A new pyrrolidone derivative with antiepileptic properties. INT SYMP MED CHEM 2004 18 Abs 5B
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UCB announces positive new products results
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574228 UCB SA PRESS RELEASE December 02
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574228 UCB announces positive new products results. UCB SA PRESS RELEASE 2004 December 02
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576835 American Epilepsy Society - 58th Annual Meeting, Novel Compounds for the Treatment of Seizures, New Orleans, LA, USA IDDB MEETING REPORT December 03-07
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576835 American Epilepsy Society - 58th Annual Meeting, Novel Compounds for the Treatment of Seizures, New Orleans, LA, USA. Pitkanen A IDDB MEETING REPORT 2004 December 03-07
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UCB 34714, a new pyrrolidone anticonvulsant, had no effect on voltage-gated potassium currents in cultured mouse hippocampal neurons
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583827
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583827 UCB 34714, a new pyrrolidone anticonvulsant, had no effect on voltage-gated potassium currents in cultured mouse hippocampal neurons. Margineanu DG, Schlobohm I, Klitgaard H EPILEPSIA 2004 45 3 116
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UCB 34714: Effect on inhibitory and excitatory neurotransmission
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583828 UCB 34714: Effect on inhibitory and excitatory neurotransmission. Rigo JM, Nguyen L, Hans G, Belachew S, Moonen G, Matagne A, Klitgaard H EPILEPSIA 2004 45 3 56
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Progress report on new antiepiletic drugs: A summary of the seventh Eilat Conference (EILAT VII)
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583836 Progress report on new antiepiletic drugs: A summary of the seventh Eilat Conference (EILAT VII). Bialer M, Johannessen SI, Kupferberg H, Levy RH, Perucca E, Tomson T EPILEPSY RES 2004 61 1-3 1-48
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UCB 34714, a new pyrrolidone derivative: Comparison with levetiracetam in hippocampal slice epilepsy models in vitro
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583861 Abs 2.246
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583861 UCB 34714, a new pyrrolidone derivative: Comparison with levetiracetam in hippocampal slice epilepsy models in vitro. Margineanu DG, Kenda B, Michel P, Matagne A, Klitgaard H EPILEPSIA 2003 44 Suppl 9 Abs 2.246
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20
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4644273656
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UCB 34714, a new pyrrolidone derivative: Comparison with levetiracetam in animal models of chronic epilepsy in vivo
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583864 Abs 2.245
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583864 UCB 34714, a new pyrrolidone derivative: Comparison with levetiracetam in animal models of chronic epilepsy in vivo. Matagne A, Kenda B, Michel P, Klitgaard H EPILEPSIA 2003 44 9 Abs 2.245
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Epilepsia
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Kenda, B.2
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4644273656
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UCB 34714, a new pyrrolidone derivative inhibits epileptiform responses in hippocampal slices in vitro
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583865 Abs P551
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583865 UCB 34714, a new pyrrolidone derivative inhibits epileptiform responses in hippocampal slices in vitro. Margineanu DG, Kenda B, Michel P, Matagne A, Klitgaard H EPILEPSIA 2003 44 Suppl 8 Abs P551
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22
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UCB 34714, a new pyrrolidine derivative suppresses seizures epileptogenesis in animal models of chronic epilepsy in vivo
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583866 Abs 072
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583866 UCB 34714, a new pyrrolidine derivative suppresses seizures epileptogenesis in animal models of chronic epilepsy in vivo. Matagne A, Kenda B, Michel P, Klitgaard H EPILEPSIA 2003 44 Suppl 8 Abs 072
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Matagne, A.1
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593753 The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B PROC NATL ACAD SCI USA 2004 101 26 9861-9866
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UCB 34714, a new pyrrolidone derivative without impact on high-and low-voltage activated calcium currents in rat isolated neurons
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599783 Abs 1.375
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599783 UCB 34714, a new pyrrolidone derivative without impact on high-and low-voltage activated calcium currents in rat isolated neurons. Kostyuk PG, Lukyanetz EA, Klitgaard H, Margineanu DG EPILEPSIA 2004 45 Suppl 7 Abs 1.375
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21344456412
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+ currents in rat cortical neurons in culture
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599786 Abs 1.388
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+ currents in rat cortical neurons in culture. Zona C, Pieri M, Klitgaard H, Margineanu DG EPILEPSIA 2004 45 Suppl 7 Abs 1.388
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14944357363
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Proof of principle in the new AED UCB 34714: Use of the photosensitivity model
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599790 Abs 2.349
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599790 Proof of principle in the new AED UCB 34714: Use of the photosensitivity model. Kasteleijn-Nolst Trenite DG, Parain D, Masnou P, Genton P, Steinhoff BJ, Hirsch E EPILEPSIA 2004 45 Suppl 7 Abs 2.349
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