Interleukin-4 induced down-regulation of skin homing receptor expression by human viral-specific CD8+ T cells may contribute to atopic risk of cutaneous infection

Clinical and Experimental Immunology

Volumn 141, Issue 1, 2005, Pages 107-115

  Seneviratne, S L ^a   Jones, L ^a   Bailey, A S ^a   Samuel, R V ^a   Black, A P ^a   Ogg, Graham S ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

CD8+ T cells; CLA; IL 12; IL 4

Indexed keywords

CD8 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FUCOSYLTRANSFERASE; HLA A ANTIGEN; HOMING RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 14; INTERLEUKIN 4; PADGEM PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; ATOPY; CONTROLLED STUDY; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFECTION RISK; INFLUENZA VIRUS A; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SKIN INFECTION; T LYMPHOCYTE; TISSUE SPECIFICITY;

ANTIGENS, NEOPLASM; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOMEGALOVIRUS; DERMATITIS, ATOPIC; DOWN-REGULATION; EPITOPES, T-LYMPHOCYTE; FLOW CYTOMETRY; HERPESVIRUS 4, HUMAN; HUMANS; INTERLEUKIN-12; INTERLEUKIN-4; MEMBRANE GLYCOPROTEINS; ORTHOMYXOVIRIDAE; RECEPTORS, LYMPHOCYTE HOMING; SKIN; SKIN DISEASES, VIRAL;

EID: 21344469913     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02823.x     Document Type: Article

References (50)

1. Fuhlbrigge RC, Kieffer JD, Armerding D et al. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature 1997; 389:978-81.
2. Fuhlbrigge RC, King SL, Dimitroff CJ et al. Direct real-time observation of E- and P-selectin-mediated rolling on cutaneous lymphocyte-associated antigen immobilized on Western blots. J Immunol 2002; 168:5645-51.
3. Teraki Y, Miyake A, Takebayashi R et al. In vivo evidence for close association of CLA expression and E-selectin binding by T cells in the inflamed skin. J Dermatol Sci 2004; 36:63-5.
4. Armerding D, Kupper TS. Functional cutaneous lymphocyte antigen can be induced in essentially all peripheral blood T lymphocytes. Int Arch Allergy Immunol 1999; 119:212-22.
5. Wagers AJ, Lowe JB, Kansas GS. An important role for the alpha 1,3 fucosyltransferase, FucT-VII, in leukocyte adhesion to E-selectin. Blood 1996; 88:2125-32.
6. Wagers AJ, Stoolman LM, Craig R et al. An sLex-deficient variant of HL60 cells exhibits high levels of adhesion to vascular selectins: further evidence that HECA-452 and CSLEX1 monoclonal antibody epitopes are not essential for high avidity binding to vascular selectins. J Immunol 1998; 160:5122-9.
7. Knibbs RN, Craig RA, Maly P et al. Alpha (1,3)-fucosyltransferase VII-dependent synthesis of P- and E-selectin ligands on cultured T lymphoblasts. J Immunol 1998; 161:6305-15.
8. Dimitroff CJ, Lee JY, Rafii S et al. CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J Cell Biol 2001; 153:1277-86.
9. Dimitroff CJ, Lee JY, Schor KS et al. Differential 1-selectin binding activities of human hematopoietic cell 1-selectin ligands, HCELL and PSGL-1. J Biol Chem 2001; 276:47623-31.
10. Sackstein R. The bone marrow is akin to skin: HCELL and the biology of hematopoietic stem cell homing. J Invest Dermatol 2004; 122:1061-9.
11. Ogg GS, Dunbar PR, Romero P et al. High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo. J Exp Med 1998; 188:1203-8.
12. Dworzak MN, Froschl G, Printz D et al. Skin-associated lymphocytes in the peripheral blood of patients with atopic dermatitis: signs of subset expansion and stimulation. J Allergy Clin Immunol 1999; 103:901-6.
13. + T cells in the blood of psoriasis patients correlates closely with the severity of their disease. Clin Exp Immunol 2001; 126:365-9.
14. Borowitz MJ, Weidner A, Olsen EA et al. Abnormalities of circulating T-cell subpopulations in patients with cutaneous T-cell lymphoma: cutaneous lymphocyte-associated antigen expression on T cells correlates with extent of disease. Leukemia 1993; 7:859-63.
15. Maly P, Thall A, Petryniak B et al. The alpha (1,3) fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell 1996; 86:643-53.
16. Picker LJ, Treer JR, Ferguson-Darnell B et al. Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells. J Immunol 1993; 150:1122-36.
17. Lim YC, Henault L, Wagers AJ et al. Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-4. J Immunol 1999; 162:3193-201.
18. + T cells by TGF-beta 1 through a p38 mitogen-activated protein kinase-dependent pathway. J Immunol 2000; 165:5011-16.
19. Akdis M, Klunker S, Schliz M et al. Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells. Eur J Immunol 2000; 30:3533-41.
20. Nakayama F, Teraki Y, Kudo T et al. Expression of cutaneous lymphocyte-associated antigen regulated by a set of glycosyltransferases in human T cells: involvement of alphal, 3-fucosyltransferase VII and betal,4-galactosyltransferase I. J Invest Dermatol 2000; 115:299-306.
21. + T cells. Clin Immunol 2004; 111:119-25.
22. + T cell trafficking to inflamed skin, role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets. J Immunol 2004; 172:857-63.
23. Campbell DJ, Butcher EC. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med 2002; 195:135-41.
24. Harris NL, Watt V, Ronchese F et al. Differential T cell function and fate in lymph node and nonlymphoid tissues. J Exp Med 2002; 195:317-26.
25. Knibbs RN, Craig RA, Natsuka S et al. The fucosyltransferase FucT-VII regulates E-selectin ligand synthesis in human T cells. J Cell Biol 1996; 133:911-20.
26. Mullins DW, Sheasley SL, Ream RM et al. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J Exp Med 2003; 198:1023-34.
27. Campbell JJ, Murphy KE, Kunkel EJ et al. CCR7 expression and memory T cell diversity in humans. J Immunol 2001; 166:877-84.
28. Koelle DM, Liu Z, McClurkan CM et al. Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virus. J Clin Invest 2002; 110:537-48.
29. Teraki Y, Miyake A, Takebayashi R et al. Homing receptor and chemokine receptor on intraepidermal T cells in psoriasis vulgaris. Clin Exp Dermatol 2004; 29:658-63.
30. Campbell JJ, Haraldsen G, Pan J et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 1999; 400:776-80.
31. Morales J, Homey B, Vicari AP et al. CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells. Proc Natl Acad Sci USA 1999; 96:14470-5.
32. + lymphocytes into lesional atopic dermatitis skin. J Invest Dermatol 2000; 115:640-6.
33. Reiss Y, Proudfoot AE, Power CA et al. CC chemokine receptor (CCR) 4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J Exp Med 2001; 194:1541-7.
34. + T cells reflects disease activity of atopic dermatitis. J Invest Dermatol 2001; 117:188-96.
35. Andrew DP, Ruffing N, Kim CH et al. C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential J Immunol 2001; 166:103-11.
36. Soler D, Humphreys TL, Spinola SM et al. CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. Blood 2003; 101:1677-82.
37. Seneviratne SL, Jones L, King AS et al. Allergen-specific CD8(+) T cells and atopic disease. J Clin Invest 2002; 110:1283-91.
38. Altman JD, Moss P, Goulder P et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 1996; 274:94-6.
39. Ogg G, Jin X, Bonhoeffer S et al. Quantitation of HIV-specific CTL and plasma load of viral RNA. Science 1998; 279:2103-6.
40. + T lymphocytes. Nature 2001; 410:106-11.
41. + T cells vary in differentiation phenotype in different persistent virus infections. Nat Med 2002; 8:379-85.
42. Cohn L, Homer RJ, Marinov A et al. Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 1997; 186:1737-47.
43. Nomura I, Goleva E, Howell MD et al. Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J Immunol 2003; 171:3262-9.
44. Haselden BM, Kay AB, Larche M. Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions. J Exp Med 1999; 189:1885-94.
45. Haselden BM, Larche M, Meng Q et al. Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or T (H) 2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalveolar fluid. J Allergy Clin Immunol 2001; 108:394-401.
46. Lodolce JP, Boone DL, Chai S et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998; 9:669-76.
47. Biedermann T, Schwarzler C, Lametschwandtner G et al. Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo. Eur J Immunol 2002; 32:3171-80.
48. Bhushan M, Bleiker TO, Ballsdon AE et al. Anti-E-selectin is ineffective in the treatment of psoriasis: a randomized trial. Br J Dermatol 2002; 146:824-31.
49. Dimitroff CJ, Bernacki RJ, Sackstein R. Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen expression: implications in modulating lymphocyte migration to skin. Blood 2003; 101:602-10.
50. Dimitroff CJ, Kupper TS, Sackstein R. Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen. J Clin Invest 2003; 112:1008-18.