Evaluation of a model for seeded isothermal batch protein crystallization

Biotechnology and Bioengineering

Volumn 91, Issue 1, 2005, Pages 84-90

  Carbone, Martina N ^a   Judge, Russell A ^b   Etzel, Mark R ^a  

^a Wisconsin Electric Machines and Power Electronics Consortium   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHARACTERIZATION; CRYSTALLIZATION; CRYSTALLOGRAPHY; DEPOSITION; DRUG PRODUCTS; MOLECULAR STRUCTURE; RATE CONSTANTS; SUPERSATURATION;

BIOPHARMACEUTICALS; BULK CRYSTALLIZATION; ISOTHERMAL CRYSTALLIZATION; PROTEIN CRYSTALLIZATION;

PROTEINS;

OVALBUMIN;

ARTICLE; COST BENEFIT ANALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; DATA ANALYSIS; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PHARMACEUTICS; PROTEIN CRYSTALLIZATION; PROTEIN PURIFICATION; SCALE UP; X RAY CRYSTALLOGRAPHY;

COMPUTER SIMULATION; CRYSTALLIZATION; KINETICS; MODELS, CHEMICAL; PROTEINS; TEMPERATURE;

EID: 21344464247     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20498     Document Type: Article

References (11)

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8. Klyushnichenko V. 2003. Protein crystallization: From HTS to kilogram-scale. Curr Opin Drug Discov Develop 6:848-854.
9. Saikumar MV, Glatz CE, Larson MA. 1998. Lysozyme crystal growth and nucleation kinetics. J Crystal Growth 187:277-288.
10. Schall CA, Riley JS, Li E, Arnold E, Wiencek JM. 1996. Application of temperature control strategies to the growth of hen egg-white lysozyme crystals. J Crystal Growth 165:299-307.
11. Tavare NS. 1987. Batch crystallizers: A review. Chem Eng Comm 61: 259-318.