Unusual venom phospholipases A2 of two primitive tree vipers Trimeresurus puniceus and Trimeresurus borneensis

FEBS Journal

Volumn 272, Issue 12, 2005, Pages 3015-3025

  Wang, Ying Ming ^a   Peng, Hao Fan ^a   Tsai, Inn Ho ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Phospholipase A2; Pylogenetic analysis; Snake venom; Trimeresurus borneensis; Trimeresurus puniceus

Indexed keywords

COMPLEMENTARY DNA; GLYCINE; PHOSPHOLIPASE A2; VIPER VENOM;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTICOAGULATION; ARTICLE; ASIA; BLOOD CLOTTING; CIRCULAR DICHROISM; DISULFIDE BOND; EDEMA; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; GENE MUTATION; GENE SEGREGATION; MELTING POINT; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; SNAKE; THROMBOCYTE AGGREGATION; TRIMERESURUS BORNEENSIS; TRIMERESURUS PUNICEUS;

AMINO ACID SEQUENCE; ANIMALS; ANTICOAGULANTS; ASIA; BLOOD COAGULATION; CIRCULAR DICHROISM; CLONING, MOLECULAR; CROTALID VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; ENZYME STABILITY; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A; PHYLOGENY; PLATELET AGGREGATION INHIBITORS; RABBITS; RATS; RATS, WISTAR; SEQUENCE ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIMERESURUS;

CROTALINAE; TRIMERESURUS; TRIMERESURUS BORNEENSIS; TRIMERESURUS PUNICEUS; VIPERINAE;

EID: 21344461436     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04715.x     Document Type: Article

References (43)

1. Malhotra A & Thorpe RS (2000) A phylogeny of the Trimeresurus group of pit vipers: new evidence from a mitochondrial gene tree. Mol Phylog Evol 16, 199-211.
2. Creer S, Malhotra A & Thorpe RS (2003) Assessing the phylogenetic utility of four mitochondrial genes and a nuclear intron in the Asian pit viper genus. Trimeresurus; separate, simultaneous, and conditional data combination analyses. Mol Biol Evol 20, 1240-1251.
3. Giannasi N, Malhotra A & Thorpe RS (2001) Nuclear and mtDNA phylogenies of the Trimeresurus complex: implications for the gene versus species tree debate. Mol Phylog Evol 19, 57-66.
4. Tsai IH, Wang YM, Chen YH, Tsai TS & Tu MC (2004) Venom phospholipases A2 of bamboo viper (Trimeresurus stejnegeri): molecular characterization, geographic variations and evidence of multiple ancestries. Biochem J 377, 215-223.
5. David P & Vogel G (1996) Snakes of Sumantra: Annotated Checklist and Key with Natural History Notes, pp. 160-167. Chimaira, Frankfurt am Main, Germany.
6. Danse JM, Gasparini S & Menez A (1997) Molecular biology of snake venom phospholipase A2. In Venom Phospholipase A2 Enzyme: Structure, Function and Mechanism (Kini RM, ed), pp. 29-71. Wiley, London.
7. Francis BR, Meng J & Kaiser II (1998) Classification of snake venom group II Phospholipases A2 according to amino acid sequences. In Enzymes from Snake Venom (Bailey GS, ed), pp. 503-544. Alaken Inc, Fort Collins, CO.
8. Scott D & Sigler PB (1994) Structure and catalytic mechanism of secretory phospholipase A2. Adv Protein Chem 45, 53-88.
9. Kini RM & Evans HJ (1997) Effect of phospholipase A2 enzymes on platelet aggregation. In Venom Phoshpholipase A2 Enzyme: Structure, Function and Mechanism (Kini RM, ed), pp. 369-387. Wiley, London.
10. Tsai IH & Wang YM (1998) Effect of site directed mutagenesis on the activity of recombinant trimucrotoxin, a neurotoxic phospholipase from Trimeresurus mucrosquamatus venom. Toxicon 36, 1591-1597.
11. Mounier CM, Luchetta P, Lecut C, Koduri RS, Faure G, Lambeau G, Valentin E, Singer A, Ghomashchi F, Beguin S, et al. (2000) Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition. Eur J Biochem 267, 4960-4969.
12. Lomonte B, Pizarro-Cerda J, Angulo Y, Gorvel JP & Moreno E (1999) Tyr → Trp-substituted peptide 115-129 of a Lys49 phospholipase A2 expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect. Biochim Biophys Acta 1461, 19-26.
13. Tsai IH, Chen YH & Wang YM (2004) Comparative proteomics and subtyping of venom phospholipases A2 and disintegrins of Protobothrops pit vipers. Biochim Biophys Acta 1702, 111-119.
14. Wang YM, Liew YF, Chang KY & Tsai IH (1999) Purification and characterization of the venom phospholipases A2 from four monotypic Crotalinae snakes. J Nat Toxins 8, 331-340.
15. Tsai IH, Chen YH, Wang YM, Tu MC & Tu T (2001) Purification, sequencing, and phylogenetic analyses of novel Lys-49 phospholipase A2 from the venoms of rattlesnakes and other pit vipers. Arch Biochem Biophys 394, 236-244.
16. Ward RJ, Monesi N, Arni RK, Larson RE & Paço-Larson ML (1995) Sequence of a cDNA encoding bothropstoxin I, a myotoxin from the venom of Bothrops jararacussu. Gene 156, 305-306.
17. Botes DP & Viljoen CC (1974) Bitis gabonica venom: the amino acid sequence of phospholipase A. J Biol Chem 249, 3827-3835.
18. Joubert FJ, Townshend GS & Botes DP (1983) Purification, some properties of two phospholipases A2 (CM-I and CM II) and the amino-acid sequence of CM-II from Bitis nasicornis (Horned Adder) venom. Hoppe-Seyler's Z Physiol Chem 326, 1717-1726.
19. Topfer-Petersen E, Calvete J, Schafer W & Henschen A (1990) Complete localization of the disulfide bridges and glycosylation sites in boar sperm acrosin. FEBS Lett 275, 139-142.
20. Freedman RB (1995) The formation of protein disulfide bonds. Curr Opin Struct Biol 5, 85-91.
21. Zhu H, Dupureur CM, Zhang X & Tsai MD (1995) Phospholipases A2 engineering. The role of disulphide bonds in structure, conformational stability, and catalytic function. Biochemistry 34, 15307-15314.
22. Janssen MJW, Verheij HM, Slotboom AJ & Egmond MR (1999) Engineering the disulphide bond patterns of secretory phospholipases A2 into porcine pancreatic isozyme. Eur J Biochem 261, 197-207.
23. Matsumura M, Becktel WJ, Levitt M & Matthews BW (1989) Stabilization of phage T4 lysozyme by engineered disulphide bonds. Proc Natl Acad Sci USA 86, 6562-6566.
24. Liu Q, Huang Q, Teng M, Weeks CM, Jelsch C, Zhang R & Niu L (2003) The crystal structure of a novel, inactive, lysine 49 PLA2 from Agkistrodon acutus venom. J Biol Chem 278, 41400-41408.
25. Ward RJ, de Azevedo WF Jr & Arni RK (1998) At the interface: crystal structures of phospholipases A2. Toxicon 36, 1623-1633.
26. Lomonte B, Yamileth A & Calderón L (2003) An overview of lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action. Toxicon 42, 885-901.
27. Francis B, Schmidt J, Yang Y, Orlando R & Kaiser II (1995) Anions and the anomalous gel filtration behavior of notexin and scutoxin. Toxicon 33, 779-789.
28. Arni RK, Fontes MRM, Barberato C, Gutiérrez JM, Diaz C & Ward RJ (1999) Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani. Arch Biochem Biophys 366, 177-182.
29. Zuliania JP, Fernandesa CM, Zamunera SR, Gutiérrez JM & Teixeira CFP (2005) Inflammatory events induced by Lys-49 and Asp-49 phospholipases A2 isolated from Bothrops asper snake venom: role of catalytic activity. Toxicon 45, 335-346.
30. Mounier C, Franken PA, Verheij HM & Bon C (1996) The anticoagulant effect of the human secretory phospholipase A2 on blood plasma and on a cell-free system is due to a phospholipid-independent mechanism of action involving the inhibition of factor Va. Eur J Biochem 237, 778-785.
31. Evans HJ & Kini RM (1997) Anticoagulant effects of phospholipases. In Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism (Kini RM, ed), pp. 353-368. Wiley, London.
32. Carredano E, Westerlund B, Persson B, Saarinen M, Ramaswamy S, Eaker D & Eklund H (1998) The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2. Toxicon 36, 75-92.
33. Tsai IH, Wang YM, Chen YH & Tu AT (2003) Geographic variations, cloning and functional analyses of the venom acidic phospholipases A2 of Crotalus viridis viridis. Arch Biochem Biophys 411, 289-296.
34. Welches W, Reardon I & Heinrikson RL (1993) An examination of structural interactions presumed to be of importance in the stabilization of phospholipase A2 dimers based upon comparative protein sequence analysis of a monomeric and dimeric enzyme from the venom of Agkistrodon p. piscivorus. J Protein Chem 12, 187-193.
35. Inada M, Crowl RM, Bekkers AC, Verheij H & Weiss J (1994) Determinants of the inhibitory action of purified 14-kDa phospholipases A2 on cell-free prothrombinase complex. J Biol Chem 269, 26338-26343.
36. Nakamura S, Nakai M, Nakashima K, Ogawa T, Shimohigashi Y, Ohno M, Kihara H, Yamane T & Ashida T (1996) Roles of lysine-69 in dimerization and activity of Trimeresurus flavoviridis venom aspartate-49-phospholipase A2. J Mol Recognit 9, 23-30.
37. Mullis KB & Faloona F (1987) Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol 155, 335-350.
38. Ogawa T, Kitajima M, Nakashima KI, Sakaki Y & Ohno M (1995) Molecular evolution of group II phospholipase A2. J Mol Evol 41, 867-877.
39. Maniatis T, Fritsch EF & Sambrook J (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
40. Verheij HM, Volwerk JJ, Jansen EHJM, Puyk WC, Dijkstra BW, Drenth J & De Haas GH (1980) Methylation of histidine-48 in pancreatic phospholipase A2: role of histidine and calcium ion in the catalytic mechanism. Biochemstry 19, 743-750.
41. Felsenstein J (1992) phylip: the PHYLogeny Inference Package, Version 3.573. Computer Program Distributed by the. University of Washington Department of Genetics, Seattle.
42. Felsenstein J (1985) Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39, 783-791.
43. Renetseder R, Brunie S, Dijkstra BW, Drenth J & Sigler PB (1985) A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox venom. J Biol Chem 260, 11627-11636.