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Volumn 55, Issue 6, 2005, Pages 303-309

Aberrant methylation and loss of expression of O6-methylguanine- DNA methyltransferase in pulmonary squamous cell carcinoma and adenocarcinoma

Author keywords

Aberrant methylation; Adenocarcinoma; Multistep carcinogenesis; O 6 methylguanine DNA methyltransferase (MGMT); Squamous cell carcinoma

Indexed keywords

ALKYLATING AGENT; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

EID: 21344457722     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2005.01830.x     Document Type: Article
Times cited : (17)

References (39)
  • 1
    • 0033577045 scopus 로고    scopus 로고
    • Molecular detection of early lung cancer
    • Gardar AF, Minna JD. Molecular detection of early lung cancer. J Natl Cancer Inst 1999; 91: 299-301.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 299-301
    • Gardar, A.F.1    Minna, J.D.2
  • 2
    • 0034201912 scopus 로고    scopus 로고
    • Evaluation of p53 gene mutation and loss of heterozygosity of 3p, 9p and p17 in precancerous lesions of 29 lung cancer patients
    • Nishisaka T, Takeshima Y, Inai K. Evaluation of p53 gene mutation and loss of heterozygosity of 3p, 9p and p17 in precancerous lesions of 29 lung cancer patients. Hiroshima J Med Sci 2000; 49: 109-16.
    • (2000) Hiroshima J Med Sci , vol.49 , pp. 109-116
    • Nishisaka, T.1    Takeshima, Y.2    Inai, K.3
  • 4
    • 9244257263 scopus 로고    scopus 로고
    • Atypical adenomatous hyperplasia and bronchoalveolar lung carcinoma: Analysis by morphometry and the expressions of p53 and carcinoembryonic antigen
    • Kitamura H, Kameda Y, Nakamura N et al. Atypical adenomatous hyperplasia and bronchoalveolar lung carcinoma: Analysis by morphometry and the expressions of p53 and carcinoembryonic antigen. Am J Surg Pathol 1996; 20: 553-62.
    • (1996) Am J Surg Pathol , vol.20 , pp. 553-562
    • Kitamura, H.1    Kameda, Y.2    Nakamura, N.3
  • 5
    • 0028924643 scopus 로고
    • Proliferative potential and p53 overexpression in precursor and early stage lesions of bronchioloalveolar lung carcinoma
    • Kitamura H, Kameda Y, Nakamura N et al. Proliferative potential and p53 overexpression in precursor and early stage lesions of bronchioloalveolar lung carcinoma. Am J Pathol 1995; 146: 876-87.
    • (1995) Am J Pathol , vol.146 , pp. 876-887
    • Kitamura, H.1    Kameda, Y.2    Nakamura, N.3
  • 6
    • 0029063625 scopus 로고
    • Small adenocarcinoma of the lung. Histologic characteristics and prognosis
    • Noguchi M, Morikawa A, Kawasaki M et al. Small adenocarcinoma of the lung. Histologic characteristics and prognosis. Cancer 1995; 75: 2844-52.
    • (1995) Cancer , vol.75 , pp. 2844-2852
    • Noguchi, M.1    Morikawa, A.2    Kawasaki, M.3
  • 7
    • 0032949035 scopus 로고    scopus 로고
    • Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma
    • Kitamura H, Kameda Y, Ito T, Hayashi H. Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma. Am J Clin Pathol 1999; 111: 610-22.
    • (1999) Am J Clin Pathol , vol.111 , pp. 610-622
    • Kitamura, H.1    Kameda, Y.2    Ito, T.3    Hayashi, H.4
  • 8
    • 0033678779 scopus 로고    scopus 로고
    • Correlation between genetic alterations and histopathological subtypes in bronchiolo-alveolar carcinoma and atypical adenomatous hyperplasia of the lung
    • Yamasaki M, Takeshima Y, Fujii S et al. Correlation between genetic alterations and histopathological subtypes in bronchiolo-alveolar carcinoma and atypical adenomatous hyperplasia of the lung. Pathol Int 2000; 50: 778-85.
    • (2000) Pathol Int , vol.50 , pp. 778-785
    • Yamasaki, M.1    Takeshima, Y.2    Fujii, S.3
  • 9
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 1999; 91: 1194-210.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 10
    • 0034679057 scopus 로고    scopus 로고
    • Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons
    • Smith LE, Denissenko MF, Bennett WP et al. Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons. J Natl Cancer Inst 2000; 92: 803-11.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 803-811
    • Smith, L.E.1    Denissenko, M.F.2    Bennett, W.P.3
  • 11
    • 0030029911 scopus 로고    scopus 로고
    • Effects of K-ras gene mutations in the development of lung lesions induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl) -1-butanone in A/J mice
    • Kawano R, Takeshima Y, Inai K. Effects of K-ras gene mutations in the development of lung lesions induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl) -1-butanone in A/J mice. Jpn J Cancer Res 1996; 87: 44-50.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 44-50
    • Kawano, R.1    Takeshima, Y.2    Inai, K.3
  • 12
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 1990; 50: 6119-29.
    • (1990) Cancer Res , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 13
    • 0017571693 scopus 로고
    • Genetic studies of the lac represser IV. Mutagenic specificity in the lacl gene of Escherichia coli
    • Coulondre C, Miller JH. Genetic studies of the lac represser IV. Mutagenic specificity in the lacl gene of Escherichia coli. J Mol Biol 1977; 117: 577-606.
    • (1977) J Mol Biol , vol.117 , pp. 577-606
    • Coulondre, C.1    Miller, J.H.2
  • 14
    • 0031428102 scopus 로고    scopus 로고
    • Benzo[a]pyrene at an environmentally relevant dose is slowly absorbed by, and extensively metabolized in, tracheal epithelium
    • Gerde P, Muggenburg BA, Thornton-Manning JR, Lewis JL, Pyon KH, Dahl AR. Benzo[a]pyrene at an environmentally relevant dose is slowly absorbed by, and extensively metabolized in, tracheal epithelium. Carcinogenesis 1997; 18: 1825-32.
    • (1997) Carcinogenesis , vol.18 , pp. 1825-1832
    • Gerde, P.1    Muggenburg, B.A.2    Thornton-Manning, J.R.3    Lewis, J.L.4    Pyon, K.H.5    Dahl, A.R.6
  • 15
    • 0032054312 scopus 로고    scopus 로고
    • A relevant dose of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is extensively metabolized and rapidly absorbed in the canine tracheal mucosa
    • Gerde P, Muggenburg BA, Stephens T, Lewis JL, Pyon KH, Dahl AR. A relevant dose of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is extensively metabolized and rapidly absorbed in the canine tracheal mucosa. Cancer Res 1998; 58: 1417-22.
    • (1998) Cancer Res , vol.58 , pp. 1417-1422
    • Gerde, P.1    Muggenburg, B.A.2    Stephens, T.3    Lewis, J.L.4    Pyon, K.H.5    Dahl, A.R.6
  • 16
    • 0032768368 scopus 로고    scopus 로고
    • P53 mutation spectrum and load: The generation of hypotheses linking the exposure of endogeneous or exogeneous carcinogens to human cancer
    • Hussain SP, Harris CC. p53 mutation spectrum and load: The generation of hypotheses linking the exposure of endogeneous or exogeneous carcinogens to human cancer. Mutat Res 1999; 428: 23-32.
    • (1999) Mutat Res , vol.428 , pp. 23-32
    • Hussain, S.P.1    Harris, C.C.2
  • 17
    • 0034124449 scopus 로고    scopus 로고
    • Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer
    • Ahrendt SA, Chow JT, Yang SC et al. Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer. Cancer Res 2000; 60: 3155-9.
    • (2000) Cancer Res , vol.60 , pp. 3155-3159
    • Ahrendt, S.A.1    Chow, J.T.2    Yang, S.C.3
  • 18
    • 0029919634 scopus 로고    scopus 로고
    • Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation
    • Hollstein M, Shomer B, Greenblatt M et al. Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation. Nucleic Acids Res 1996; 24: 141-6.
    • (1996) Nucleic Acids Res , vol.24 , pp. 141-146
    • Hollstein, M.1    Shomer, B.2    Greenblatt, M.3
  • 19
    • 0035890742 scopus 로고    scopus 로고
    • 6-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer
    • 6- Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer. Cancer Res 2001; 61: 8113-17.
    • (2001) Cancer Res , vol.61 , pp. 8113-8117
    • Wolf, P.1    Hu, Y.C.2    Doffek, K.3    Sidransky, D.4    Ahrendt, S.A.5
  • 20
    • 0041438629 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene: More common in lung adenocarcinomas.from never-smokers than smokers and associated with tumor progression
    • 6-methylguanine-DNA methyltransferase gene: More common in lung adenocarcinomas.from never-smokers than smokers and associated with tumor progression. Cancer Res 2003; 63: 4842-8.
    • (2003) Cancer Res , vol.63 , pp. 4842-4848
    • Pulling, L.C.1    Divine, K.K.2    Klinge, D.M.3
  • 21
    • 0030912190 scopus 로고    scopus 로고
    • Revisions in the international system for staging lung cancer
    • Mountain CF. Revisions in the international system for staging lung cancer. Chest 1997; 111: 1710-17.
    • (1997) Chest , vol.111 , pp. 1710-1717
    • Mountain, C.F.1
  • 22
    • 0036145156 scopus 로고    scopus 로고
    • Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
    • Esteller M, Herman JG. Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J Pathol 2002; 196: 1-7.
    • (2002) J Pathol , vol.196 , pp. 1-7
    • Esteller, M.1    Herman, J.G.2
  • 23
    • 0031878857 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase expression in human lung carcinomas
    • 6-methylguanine-DNA methyltransferase expression in human lung carcinomas. Carcinogenesis 1998; 19: 1247-50.
    • (1998) Carcinogenesis , vol.19 , pp. 1247-1250
    • Mattern, J.1    Koomagi, R.2    Volm, M.3
  • 24
    • 0028227862 scopus 로고
    • 6- methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells
    • 6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells. J Biol Chem 1994; 269: 17228-37.
    • (1994) J Biol Chem , vol.269 , pp. 17228-17237
    • Costello, J.F.1    Futscher, B.W.2    Tano, K.3    Graunke, D.M.4    Pieper, R.O.5
  • 25
    • 0030823671 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene
    • 6-methylguanine-DNA methyltransferase gene. Cancer Res 1997; 57: 3672-7.
    • (1997) Cancer Res , vol.57 , pp. 3672-3677
    • Qian, X.C.1    Brent, T.P.2
  • 26
    • 0030874380 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcrip-start site and silencing of the gene
    • 6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcrip-start site and silencing of the gene. Mol Cell Biol 1997; 17: 5612-19.
    • (1997) Mol Cell Biol , vol.17 , pp. 5612-5619
    • Watts, G.S.1    Pieper, R.O.2    Costello, J.F.3    Peng, Y.M.4    Dalton, W.S.5    Futscher, B.W.6
  • 27
    • 0022931463 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues
    • 6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues. Carcinogenesis 1986; 7: 745-9.
    • (1986) Carcinogenesis , vol.7 , pp. 745-749
    • Gerson, S.L.1    Trey, J.E.2    Miller, K.3    Berger, N.A.4
  • 29
    • 0025195656 scopus 로고
    • 6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction technique
    • 6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction technique. Cancer Commun 1990; 2: 13-20.
    • (1990) Cancer Commun , vol.2 , pp. 13-20
    • Pieper, R.O.1    Futscher, B.W.2    Dong, Q.3    Ellis, T.M.4    Erickson, L.C.5
  • 30
    • 4344672497 scopus 로고    scopus 로고
    • Aberrant methylation of p14ARF, p15INK4b and p16INK4a genes and location of the primary site in pulmonary squamous cell carcinoma
    • Osamu F, Yukio T, Hirokazu A, Hajime I, Nobuoki K, Kouki I. Aberrant methylation of p14ARF, p15INK4b and p16INK4a genes and location of the primary site in pulmonary squamous cell carcinoma. Pathol Int 2004; 54: 549-55.
    • (2004) Pathol Int , vol.54 , pp. 549-555
    • Osamu, F.1    Yukio, T.2    Hirokazu, A.3    Hajime, I.4    Nobuoki, K.5    Kouki, I.6
  • 31
    • 20044383744 scopus 로고    scopus 로고
    • Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers
    • Divine KK, Pulling LC, Marron-Terada PG et al. Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers. Int J Cancer 2005; 114: 400-5.
    • (2005) Int J Cancer , vol.114 , pp. 400-405
    • Divine, K.K.1    Pulling, L.C.2    Marron-Terada, P.G.3
  • 32
    • 2942620221 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene: Epigenetic silencing and prognostic value in head and neck squamous cell carcinoma
    • 6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2004; 13: 967-75.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 967-975
    • Zuo, C.1    Ai, L.2    Ratliff, P.3
  • 34
    • 12244297095 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: Associations with clinical outcome
    • 6-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: Associations with clinical outcome. Clin Cancer Res 2003; 9: 223-7.
    • (2003) Clin Cancer Res , vol.9 , pp. 223-227
    • Brabender, J.1    Usadel, H.2    Metzger, R.3
  • 35
    • 0036899938 scopus 로고    scopus 로고
    • Aberrant promoter methylation in Chinese patients with non-small cell lung cancer: Patterns in primary tumors and potential diagnostic application in bronchoalevolar lavage
    • Chan EC, Lam SY, Tsang KW et al. Aberrant promoter methylation in Chinese patients with non-small cell lung cancer: Patterns in primary tumors and potential diagnostic application in bronchoalevolar lavage. Clin Cancer Res 2002; 8: 3741-6.
    • (2002) Clin Cancer Res , vol.8 , pp. 3741-3746
    • Chan, E.C.1    Lam, S.Y.2    Tsang, K.W.3
  • 36
    • 1842426642 scopus 로고    scopus 로고
    • Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer
    • Topaloglu O, Hoque MO, Tokumaru Y et al. Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer. Clin Cancer Res 2004; 10: 2284-8.
    • (2004) Clin Cancer Res , vol.10 , pp. 2284-2288
    • Topaloglu, O.1    Hoque, M.O.2    Tokumaru, Y.3
  • 37
    • 0036005894 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in human lung adenocarcinoma relates to high-grade histology and worse prognosis among smokers
    • 6-methylguanine-DNA methyltransferase in human lung adenocarcinoma relates to high-grade histology and worse prognosis among smokers. Jpn J Cancer Res 2002; 93: 184-9.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 184-189
    • Hayashi, H.1    Yazawa, T.2    Okudela, K.3
  • 38
    • 2942560190 scopus 로고    scopus 로고
    • Maspin expression in normal lung and non-small-cell lung cancers: Cellular property-associated expression under the control of promoter DNA methylation
    • Yatabe Y, Mitsudomi T, Takahashi T. Maspin expression in normal lung and non-small-cell lung cancers: Cellular property-associated expression under the control of promoter DNA methylation. Oncogene 2004; 23: 4041-9.
    • (2004) Oncogene , vol.23 , pp. 4041-4049
    • Yatabe, Y.1    Mitsudomi, T.2    Takahashi, T.3
  • 39
    • 0035870282 scopus 로고    scopus 로고
    • P16 (INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer
    • Kim DH, Nelson HH, Wiencke JK et al. p16 (INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res 2001; 61: 3419-24.
    • (2001) Cancer Res , vol.61 , pp. 3419-3424
    • Kim, D.H.1    Nelson, H.H.2    Wiencke, J.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.