Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: Effective induction of tumor-specific CD8 + CTL response

Journal of Cancer Research and Clinical Oncology

Volumn 131, Issue 7, 2005, Pages 468-478

  Pan, Jianping ^a   Zhang, Minghui ^b   Wang, Jianli ^a   Wang, Qingqing ^a   Xia, Dajing ^a   Sun, Wenji ^a   Zhang, Lihuang ^a   Yu, Hai ^a   Cao, Xuetao ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cross presentation; Dendritic cells; Gene therapy; Interferon ; Melanoma

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CD8 ANTIGEN; DENDRITIC CELL VACCINE; GAMMA INTERFERON; NITRIC OXIDE; RECOMBINANT GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY TEST; DENDRITIC CELL; DNA MODIFICATION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FIBROBLAST; GENETIC CODE; GENETIC TRANSFECTION; IMMUNE RESPONSE; IMMUNOASSAY; IMMUNOSTIMULATION; LYMPHOCYTE ACTIVATION; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; TUMOR IMMUNITY; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CD8-POSITIVE T-LYMPHOCYTES; CHROMIUM; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INJECTIONS, INTRALESIONAL; INTERFERON TYPE II; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NITRIC OXIDE; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 21344453577     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-004-0651-y     Document Type: Article

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