메뉴 건너뛰기




Volumn 27, Issue 1, 2005, Pages 37-48

CD4 T cells in tumor immunity

Author keywords

CD4 T cells; MHC class II; Th Th cell cooperation; Tumor immunity

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TUMOR ANTIGEN;

EID: 21344438670     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00281-004-0193-z     Document Type: Review
Times cited : (82)

References (82)
  • 1
    • 84991131571 scopus 로고
    • Immunological surveillance in neoplasia
    • Burnet FM (1971) Immunological surveillance in neoplasia. Transplant Rev 7:3
    • (1971) Transplant Rev , vol.7 , pp. 3
    • Burnet, F.M.1
  • 3
    • 0028361047 scopus 로고
    • Role of cytokines in determining T-lymphocyte function
    • O'Garra A, Murphy K (1994) Role of cytokines in determining T-lymphocyte function. Curr Opin Immunol 6:458
    • (1994) Curr Opin Immunol , vol.6 , pp. 458
    • O'Garra, A.1    Murphy, K.2
  • 4
    • 0037350545 scopus 로고    scopus 로고
    • Immunotherapy: Past, present and future
    • Waldmann TA (2003) Immunotherapy: past, present and future. Nat Med 9:269
    • (2003) Nat Med , vol.9 , pp. 269
    • Waldmann, T.A.1
  • 5
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler JW, Roehm N, Marrack P (1987) T cell tolerance by clonal elimination in the thymus. Cell 49:273
    • (1987) Cell , vol.49 , pp. 273
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 6
    • 1542680896 scopus 로고    scopus 로고
    • Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8
    • Cobbold SP, Adams E, Marshall SE, et al (1996) Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8. Immunol Rev 149:5
    • (1996) Immunol Rev , vol.149 , pp. 5
    • Cobbold, S.P.1    Adams, E.2    Marshall, S.E.3
  • 7
    • 0033514923 scopus 로고    scopus 로고
    • Immune surveillance against a solid tumor fails because of immunological ignorance
    • Ochsenbein AF, Klenerman P, Karrer U, et al (1999) Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci USA 96:2233
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2233
    • Ochsenbein, A.F.1    Klenerman, P.2    Karrer, U.3
  • 8
    • 0027407108 scopus 로고
    • Dominance and crypticity of T cell antigenic determinants
    • Sercarz EE, Lehmann PV, Ametani A, et al (1993) Dominance and crypticity of T cell antigenic determinants. Annu Rev Immunol 11:729
    • (1993) Annu Rev Immunol , vol.11 , pp. 729
    • Sercarz, E.E.1    Lehmann, P.V.2    Ametani, A.3
  • 9
    • 0001967883 scopus 로고
    • The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation
    • Mitchison NA (1971) The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation. Eur J Immunol 1:18
    • (1971) Eur J Immunol , vol.1 , pp. 18
    • Mitchison, N.A.1
  • 10
    • 0020077493 scopus 로고
    • Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
    • Keene JA, Forman J (1982) Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J Exp Med 155:768
    • (1982) J Exp Med , vol.155 , pp. 768
    • Keene, J.A.1    Forman, J.2
  • 11
    • 0025918153 scopus 로고
    • Helper T-cell subsets: Phenotype, function and the role of lymphokines in regulating their development
    • Swain SL, Bradley LM, Croft M, et al (1991) Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev 123:115
    • (1991) Immunol Rev , vol.123 , pp. 115
    • Swain, S.L.1    Bradley, L.M.2    Croft, M.3
  • 12
    • 0030175602 scopus 로고    scopus 로고
    • Type 1 and type 2: A fundamental dichotomy for all T-cell subsets
    • Carter LL, Dutton RW (1996) Type 1 and type 2: a fundamental dichotomy for all T-cell subsets. Curr Opin Immunol 8:336
    • (1996) Curr Opin Immunol , vol.8 , pp. 336
    • Carter, L.L.1    Dutton, R.W.2
  • 14
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock DJ, Shen H (2003) Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300:337
    • (2003) Science , vol.300 , pp. 337
    • Shedlock, D.J.1    Shen, H.2
  • 15
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun JC, Bevan MJ (2003) Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300:339
    • (2003) Science , vol.300 , pp. 339
    • Sun, J.C.1    Bevan, M.J.2
  • 17
    • 0037348836 scopus 로고    scopus 로고
    • Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus
    • Langlade-Demoyen P, Garcia-Pons F, Castiglioni P, et al (2003) Role of T cell help and endoplasmic reticulum targeting in protective CTL response against influenza virus. Eur J Immunol 33:720
    • (2003) Eur J Immunol , vol.33 , pp. 720
    • Langlade-Demoyen, P.1    Garcia-Pons, F.2    Castiglioni, P.3
  • 18
    • 0032473562 scopus 로고    scopus 로고
    • Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors
    • Ossendorp F, Mengede E, Camps M, et al (1998) Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors. J Exp Med 187:693
    • (1998) J Exp Med , vol.187 , pp. 693
    • Ossendorp, F.1    Mengede, E.2    Camps, M.3
  • 20
    • 0021206662 scopus 로고
    • - T cells do not necessarily require recruitment of host's cytotoxic T cell precursors for implementation of in vivo immunity
    • - T cells do not necessarily require recruitment of host's cytotoxic T cell precursors for implementation of in vivo immunity. J Immunol 133:1671
    • (1984) J Immunol , vol.133 , pp. 1671
    • Fujiwara, H.1    Fukuzawa, M.2    Yoshioka, T.3
  • 23
    • 0032433127 scopus 로고    scopus 로고
    • The central role of CD4(+) T cells in the antitumor immune response
    • Hung K, Hayashi R, Lafond-Walker A, et al (1998) The central role of CD4(+) T cells in the antitumor immune response. J Exp Med 188:2357
    • (1998) J Exp Med , vol.188 , pp. 2357
    • Hung, K.1    Hayashi, R.2    Lafond-Walker, A.3
  • 24
    • 0033061017 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte activation by cross-priming
    • Heath WR, Carbone FR (1999) Cytotoxic T lymphocyte activation by cross-priming. Curr Opin Immunol 11:314
    • (1999) Curr Opin Immunol , vol.11 , pp. 314
    • Heath, W.R.1    Carbone, F.R.2
  • 25
    • 0033103147 scopus 로고    scopus 로고
    • Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells
    • Pieper R, Christian RE, Gonzales MI, et al (1999) Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells. J Exp Med 189:757
    • (1999) J Exp Med , vol.189 , pp. 757
    • Pieper, R.1    Christian, R.E.2    Gonzales, M.I.3
  • 26
    • 0033577804 scopus 로고    scopus 로고
    • Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells
    • Wang RF, Wang X, Rosenberg SA (1999) Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells. J Exp Med 189:1659
    • (1999) J Exp Med , vol.189 , pp. 1659
    • Wang, R.F.1    Wang, X.2    Rosenberg, S.A.3
  • 27
    • 0033591429 scopus 로고    scopus 로고
    • Cloning genes encoding MHC class II-restricted antigens: Mutated CDC27 as a tumor antigen
    • Wang RF, Wang X, Atwood AC, et al (1999) Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. Science 284:1351
    • (1999) Science , vol.284 , pp. 1351
    • Wang, R.F.1    Wang, X.2    Atwood, A.C.3
  • 28
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • Greenberg PD (1991) Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Adv Immunol 49:281
    • (1991) Adv Immunol , vol.49 , pp. 281
    • Greenberg, P.D.1
  • 29
    • 0028500836 scopus 로고
    • Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors
    • Dighe AS, Richards E, Old LJ, et al (1994) Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity 1:447
    • (1994) Immunity , vol.1 , pp. 447
    • Dighe, A.S.1    Richards, E.2    Old, L.J.3
  • 30
    • 0020573520 scopus 로고
    • Human tumor necrosis factor produced by human B-cell lines: Synergistic cytotoxic interaction with human interferon
    • Williamson BD, Carswell EA, Rubin BY, et al (1983) Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon. Proc Natl Acad Sci USA 80:5397
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 5397
    • Williamson, B.D.1    Carswell, E.A.2    Rubin, B.Y.3
  • 31
    • 0022633381 scopus 로고
    • Recombinant tumor necrosis factor: Its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines
    • Fransen L, Van der Heyden J, Ruysschaert R, et al (1986) Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines. Eur J Cancer Clin Oncol 22:419
    • (1986) Eur J Cancer Clin Oncol , vol.22 , pp. 419
    • Fransen, L.1    Van Der Heyden, J.2    Ruysschaert, R.3
  • 32
    • 17344383269 scopus 로고    scopus 로고
    • Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis
    • Coughlin CM, Salhany KE, Gee MS, et al (1998) Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis. Immunity 9:25
    • (1998) Immunity , vol.9 , pp. 25
    • Coughlin, C.M.1    Salhany, K.E.2    Gee, M.S.3
  • 33
    • 0033662405 scopus 로고    scopus 로고
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells. Immunity 12:677
    • (2000) Immunity , vol.12 , pp. 677
    • Qin, Z.1    Blankenstein, T.2
  • 34
    • 0034700109 scopus 로고    scopus 로고
    • Functional cooperation between Th cell determinants
    • Gerloni M, Xiong S, Mukerjee S, et al (2000) Functional cooperation between Th cell determinants. Proc Natl Acad Sci USA 97:13269
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13269
    • Gerloni, M.1    Xiong, S.2    Mukerjee, S.3
  • 35
    • 0021132973 scopus 로고
    • Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors
    • Hilkens J, Buijs F, Hilgers J, et al (1984) Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors. Int J Cancer 34:197
    • (1984) Int J Cancer , vol.34 , pp. 197
    • Hilkens, J.1    Buijs, F.2    Hilgers, J.3
  • 36
    • 0030466993 scopus 로고    scopus 로고
    • Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells
    • Lloyd KO, Burchell J, Kudryashov V, et al (1996) Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. J Biol Chem 271:33325
    • (1996) J Biol Chem , vol.271 , pp. 33325
    • Lloyd, K.O.1    Burchell, J.2    Kudryashov, V.3
  • 37
    • 0033120061 scopus 로고    scopus 로고
    • Activation of CD4 T cells by somatic transgenesis induces generalized immunity of uncommitted T cells and immunologic memory
    • Gerloni M, Miner KT, Xiong S, et al (1999) Activation of CD4 T cells by somatic transgenesis induces generalized immunity of uncommitted T cells and immunologic memory. J Immunol 162:3782
    • (1999) J Immunol , vol.162 , pp. 3782
    • Gerloni, M.1    Miner, K.T.2    Xiong, S.3
  • 38
    • 0029918564 scopus 로고    scopus 로고
    • Induction of cellular immunity in chimpanzees to human tumor-associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells
    • Pecher G, Finn OJ (1996) Induction of cellular immunity in chimpanzees to human tumor-associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells. Proc Natl Acad Sci USA 93:1699
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1699
    • Pecher, G.1    Finn, O.J.2
  • 39
    • 13144268565 scopus 로고    scopus 로고
    • Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells
    • Gong J, Chen D, Kashiwaba M, et al (1998) Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells. Proc Natl Acad Sci USA 95:6279
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6279
    • Gong, J.1    Chen, D.2    Kashiwaba, M.3
  • 40
    • 0035339389 scopus 로고    scopus 로고
    • Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection
    • Soares MM, Mehta V, Finn OJ (2001) Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection. J Immunol 166:6555
    • (2001) J Immunol , vol.166 , pp. 6555
    • Soares, M.M.1    Mehta, V.2    Finn, O.J.3
  • 41
    • 0032533812 scopus 로고    scopus 로고
    • + lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice
    • + lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice. J Immunol 161:5500
    • (1998) J Immunol , vol.161 , pp. 5500
    • Tempero, R.M.1    VanLith, M.L.2    Morikane, K.3
  • 42
    • 0014941813 scopus 로고
    • A theory of self-nonself discrimination
    • Bretscher P, Cohn M (1970) A theory of self-nonself discrimination. Science 169:1042
    • (1970) Science , vol.169 , pp. 1042
    • Bretscher, P.1    Cohn, M.2
  • 43
    • 0016588323 scopus 로고
    • A disquisition on suppressor T cells
    • Gershon RK (1975) A disquisition on suppressor T cells. Transplant Rev 26:170
    • (1975) Transplant Rev , vol.26 , pp. 170
    • Gershon, R.K.1
  • 46
    • 1842581857 scopus 로고    scopus 로고
    • + T cells restrain the maturation and antigen-presenting function of dendritic cells
    • + T cells restrain the maturation and antigen-presenting function of dendritic cells. J Immunol 172:4676
    • (2004) J Immunol , vol.172 , pp. 4676
    • Misra, N.1    Bayry, J.2    Lacroix-Desmazes, S.3
  • 47
    • 11944274070 scopus 로고    scopus 로고
    • Reviving suppression?
    • Cantor H (2004) Reviving suppression? Nat Immunol 5:347
    • (2004) Nat Immunol , vol.5 , pp. 347
    • Cantor, H.1
  • 48
    • 0026647293 scopus 로고
    • + T cells in murine experimental allergic encephalomyelitis
    • + T cells in murine experimental allergic encephalomyelitis. Science 256:1213
    • (1992) Science , vol.256 , pp. 1213
    • Jiang, H.1    Zhang, S.I.2    Pernis, B.3
  • 49
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North RJ (1982) Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J Exp Med 155:1063
    • (1982) J Exp Med , vol.155 , pp. 1063
    • North, R.J.1
  • 50
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163:5211
    • (1999) J Immunol , vol.163 , pp. 5211
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 51
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, et al (1999) Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res 59:3128
    • (1999) Cancer Res , vol.59 , pp. 3128
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3
  • 52
    • 4444345447 scopus 로고    scopus 로고
    • A simple method to cure established tumors by inflammatory killing of normal cells
    • Daniels GA, Sanchez-Perez L, Diaz RM, et al (2004) A simple method to cure established tumors by inflammatory killing of normal cells. Nat Biotechnol 22:1125
    • (2004) Nat Biotechnol , vol.22 , pp. 1125
    • Daniels, G.A.1    Sanchez-Perez, L.2    Diaz, R.M.3
  • 53
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP, Duivenvoorde LM van, Elsas A van, et al (2001) Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194:823
    • (2001) J Exp Med , vol.194 , pp. 823
    • Sutmuller, R.P.1    Van Duivenvoorde, L.M.2    Van Elsas, A.3
  • 54
    • 1642378018 scopus 로고    scopus 로고
    • + regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    • + regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur J Immunol 34:336
    • (2004) Eur J Immunol , vol.34 , pp. 336
    • Ghiringhelli, F.1    Larmonier, N.2    Schmitt, E.3
  • 55
    • 0037450746 scopus 로고    scopus 로고
    • + regulatory T cells that express toll-like receptors
    • + regulatory T cells that express toll-like receptors. J Exp Med 197:397
    • (2003) J Exp Med , vol.197 , pp. 397
    • Sakaguchi, S.1
  • 56
    • 0037217371 scopus 로고    scopus 로고
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens. J Immunother 26:85
    • (2003) J Immunother , vol.26 , pp. 85
    • Javia, L.R.1    Rosenberg, S.A.2
  • 57
    • 3142737258 scopus 로고    scopus 로고
    • high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 173:1444
    • (2004) J Immunol , vol.173 , pp. 1444
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3
  • 58
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, et al (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10:942
    • (2004) Nat Med , vol.10 , pp. 942
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 59
    • 0345538675 scopus 로고    scopus 로고
    • PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia
    • Padua RA, Larghero J, Robin M, et al (2003) PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia. Nat Med 9:1413
    • (2003) Nat Med , vol.9 , pp. 1413
    • Padua, R.A.1    Larghero, J.2    Robin, M.3
  • 60
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann PV, Forsthuber T, Miller A, et al (1992) Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358:155
    • (1992) Nature , vol.358 , pp. 155
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3
  • 61
    • 1642497640 scopus 로고    scopus 로고
    • + regulatory T cells and their ligands: Implications for immunotherapy
    • + regulatory T cells and their ligands: implications for immunotherapy. Immunity 20:107
    • (2004) Immunity , vol.20 , pp. 107
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3
  • 62
    • 0031974381 scopus 로고    scopus 로고
    • + T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase
    • + T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase. Cancer Res 58:296
    • (1998) Cancer Res , vol.58 , pp. 296
    • Kobayashi, H.1    Kokubo, T.2    Sato, K.3
  • 63
    • 0031914902 scopus 로고    scopus 로고
    • Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada disease patient
    • Kobayashi H, Kokubo T, Takahashi M, et al (1998) Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada disease patient. Immunogenetics 47:398
    • (1998) Immunogenetics , vol.47 , pp. 398
    • Kobayashi, H.1    Kokubo, T.2    Takahashi, M.3
  • 64
    • 0037309192 scopus 로고    scopus 로고
    • Normal tissue depresses while tumor tissue enhances human T cell responses in vivo to a novel self/tumor melanoma antigen, OA1
    • Touloukian CE, Leitner WW, Schnur RE, et al (2003) Normal tissue depresses while tumor tissue enhances human T cell responses in vivo to a novel self/tumor melanoma antigen, OA1. J Immunol 170:1579
    • (2003) J Immunol , vol.170 , pp. 1579
    • Touloukian, C.E.1    Leitner, W.W.2    Schnur, R.E.3
  • 65
    • 0034602674 scopus 로고    scopus 로고
    • Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells
    • Zarour HM, Kirkwood JM, Kierstead LS, et al (2000) Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells. Proc Natl Acad Sci USA 97:400
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 400
    • Zarour, H.M.1    Kirkwood, J.M.2    Kierstead, L.S.3
  • 66
    • 0031690656 scopus 로고    scopus 로고
    • Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells
    • Li K, Adibzadeh M, Halder T, et al (1998) Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells. Cancer Immunol Immunother 47:32
    • (1998) Cancer Immunol Immunother , vol.47 , pp. 32
    • Li, K.1    Adibzadeh, M.2    Halder, T.3
  • 67
    • 0034176020 scopus 로고    scopus 로고
    • Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic mice
    • Touloukian CE, Leitner WW, Topalian SL, et al (2000) Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic mice. J Immunol 164:3535
    • (2000) J Immunol , vol.164 , pp. 3535
    • Touloukian, C.E.1    Leitner, W.W.2    Topalian, S.L.3
  • 68
    • 0033103512 scopus 로고    scopus 로고
    • Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes
    • Chaux P, Vantomme V, Stroobant V, et al (1999) Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes. J Exp Med 189:767
    • (1999) J Exp Med , vol.189 , pp. 767
    • Chaux, P.1    Vantomme, V.2    Stroobant, V.3
  • 69
    • 0033103192 scopus 로고    scopus 로고
    • Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11
    • Manici S, Sturniolo T, Imro MA, et al (1999) Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11. J Exp Med 189:871
    • (1999) J Exp Med , vol.189 , pp. 871
    • Manici, S.1    Sturniolo, T.2    Imro, M.A.3
  • 70
    • 0345734268 scopus 로고    scopus 로고
    • CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope
    • Campi G, Crosti M, Consogno G, et al (2003) CD4(+) T cells from healthy subjects and colon cancer patients recognize a carcinoembryonic antigen-specific immunodominant epitope. Cancer Res 63:8481
    • (2003) Cancer Res , vol.63 , pp. 8481
    • Campi, G.1    Crosti, M.2    Consogno, G.3
  • 71
    • 0034662263 scopus 로고    scopus 로고
    • + T cell epitopes from NY-ESO-1 presented by HLA-DR molecules
    • + T cell epitopes from NY-ESO-1 presented by HLA-DR molecules. J Immunol 165:1153
    • (2000) J Immunol , vol.165 , pp. 1153
    • Zeng, G.1    Touloukian, C.E.2    Wang, X.3
  • 73
    • 0035957422 scopus 로고    scopus 로고
    • CD4(+) T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: Association with NY-ESO-1 antibody production
    • Zeng G, Wang X, Robbins PF, et al (2001) CD4(+) T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: association with NY-ESO-1 antibody production. Proc Natl Acad Sci USA 98:3964
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3964
    • Zeng, G.1    Wang, X.2    Robbins, P.F.3
  • 75
    • 0142219890 scopus 로고    scopus 로고
    • Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes
    • Maccalli C, Li YF, El-Gamil M, et al (2003) Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes. Cancer Res 63:6735
    • (2003) Cancer Res , vol.63 , pp. 6735
    • Maccalli, C.1    Li, Y.F.2    El-Gamil, M.3
  • 77
    • 0034006703 scopus 로고    scopus 로고
    • Delayed-type hypersensitivity response is a predictor of peripheral blood T-cell immunity after HER-2/neu peptide immunization
    • Disis ML, Schiffman K, Gooley TA, et al (2000) Delayed-type hypersensitivity response is a predictor of peripheral blood T-cell immunity after HER-2/neu peptide immunization. Clin Cancer Res 6:1347
    • (2000) Clin Cancer Res , vol.6 , pp. 1347
    • Disis, M.L.1    Schiffman, K.2    Gooley, T.A.3
  • 80
    • 0142157136 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes
    • Schroers R, Shen L, Rollins L, et al (2003) Human telomerase reverse transcriptase-specific T-helper responses induced by promiscuous major histocompatibility complex class II-restricted epitopes. Clin Cancer Res 9:4743
    • (2003) Clin Cancer Res , vol.9 , pp. 4743
    • Schroers, R.1    Shen, L.2    Rollins, L.3
  • 82
    • 0038176078 scopus 로고    scopus 로고
    • Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1
    • Kruger S, Schroers R, Rooney CM, et al (2003) Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1. J Immunother 26:212
    • (2003) J Immunother , vol.26 , pp. 212
    • Kruger, S.1    Schroers, R.2    Rooney, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.