Engineering and functional evaluation of a single-chain antibody against HIV-1 external glycoprotein gp120

Clinical and Experimental Immunology

Volumn 141, Issue 1, 2005, Pages 72-80

  Wang, H W ^a   Cole, D ^c   Jiang, W Z ^b   Jin, H T ^b   Fu, N ^a   Chen, Z L ^a   Jin, Ning Yi ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Glycoprotein; gp120; HIV 1; mAb; scFv

Indexed keywords

CD4 ANTIGEN; COMPLEMENTARY DNA; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; NEUTRALIZING ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE EXPRESSION; GENETIC ENGINEERING; HELA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYBRIDOMA CELL CULTURE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS INHIBITION; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BASE SEQUENCE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; GENES, IMMUNOGLOBULIN; GENETIC VECTORS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

EID: 21344434307     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02826.x     Document Type: Article

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