Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of Daidzein in cultured human Ishikawa cells

Toxicology Letters

Volumn 158, Issue 1, 2005, Pages 72-86

  Lehmann, L ^a   Esch, H L ^a   Wagner, J ^a   Rohnstock, L ^a   Metzler, M ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

Daidzein; Equol; Estrogen; Ishikawa cells; Isoflavones; Micronuclei

Indexed keywords

3' HYDROXYDAIDZEIN; 6 HYDROXYDAIDZEIN; ALKALINE PHOSPHATASE; DAIDZEIN; DRUG METABOLITE; EQUOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CENTROMERE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG HYDROXYLATION; DRUG SAFETY; DRUG SCREENING; ENDOMETRIUM CARCINOMA; ENZYME ACTIVITY; ESTROGEN ACTIVITY; GENE EXPRESSION; GENE INDUCTION; GENOTOXICITY; HUMAN; HUMAN CELL; MICRONUCLEUS; MITOSIS SPINDLE; OBSERVATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING;

ADENOCARCINOMA; ALKALINE PHOSPHATASE; CELL CYCLE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOMETRIAL NEOPLASMS; ENZYME INDUCTION; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION; HUMANS; ISOFLAVONES; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MITOTIC SPINDLE APPARATUS; MUTAGENS; PHYTOESTROGENS; RNA, MESSENGER;

EID: 21344433029     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.02.011     Document Type: Article

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