메뉴 건너뛰기




Volumn 14, Issue 7, 2005, Pages 535-542

Characterization of transgenic mice with the expression of phenylalanine hydroxylase and GTP cyclohydrolase I in the skin

Author keywords

Metabolic diseases; Phenylketonuria; Skin; Transgenic models

Indexed keywords

CYTOKERATIN 1; CYTOKERATIN 14; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; INVOLUCRIN; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; RNA;

EID: 21244503093     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2005.00326.x     Document Type: Article
Times cited : (6)

References (24)
  • 1
    • 0034501382 scopus 로고    scopus 로고
    • Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes
    • Christensen R, Kolvraa S, Blaese R M, Jensen T G. Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes. Gene Ther 2000: 7: 1971-1978.
    • (2000) Gene Ther. , vol.7 , pp. 1971-1978
    • Christensen, R.1    Kolvraa, S.2    Blaese, R.M.3    Jensen, T.G.4
  • 2
    • 3242766095 scopus 로고    scopus 로고
    • Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice
    • Mochizuki S, Mizukami H, Ogura T et al. Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice. Gene Ther 2004: 11: 1081-1086.
    • (2004) Gene Ther. , vol.11 , pp. 1081-1086
    • Mochizuki, S.1    Mizukami, H.2    Ogura, T.3
  • 3
    • 0028464358 scopus 로고
    • Gene therapy for phenylketonuria: Phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer
    • Fang B, Eisensmith R C, Li X H et al. Gene therapy for phenylketonuria: phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer. Gene Ther 1994: 1: 247-254.
    • (1994) Gene Ther. , vol.1 , pp. 247-254
    • Fang, B.1    Eisensmith, R.C.2    Li, X.H.3
  • 4
    • 0032939161 scopus 로고    scopus 로고
    • Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer
    • Nagasaki Y, Matsubara Y, Takano H et al. Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. Pediatr Res 1999: 45: 465-473.
    • (1999) Pediatr. Res. , vol.45 , pp. 465-473
    • Nagasaki, Y.1    Matsubara, Y.2    Takano, H.3
  • 5
    • 0031834511 scopus 로고    scopus 로고
    • Metabolic engineering as therapy for inborn errors of metabolism - Development of mice with phenylalanine hydroxylase expression in muscle
    • Harding C O, Wild K, Chang D, Messing A, Wolff J A. Metabolic engineering as therapy for inborn errors of metabolism - development of mice with phenylalanine hydroxylase expression in muscle. Gene Ther 1998: 5: 677-683.
    • (1998) Gene Ther. , vol.5 , pp. 677-683
    • Harding, C.O.1    Wild, K.2    Chang, D.3    Messing, A.4    Wolff, J.A.5
  • 6
    • 0346838306 scopus 로고    scopus 로고
    • Expression of phenylalanine hydroxylase (PAH) in erythrogenic bone marrow does not correct hyperphenylalaninemia in Pahenu2 mice
    • Harding C O, Neff M, Jones K, Wild K, Wolff J A. Expression of phenylalanine hydroxylase (PAH) in erythrogenic bone marrow does not correct hyperphenylalaninemia in Pahenu2 mice. J Gene Med 2003: 5: 984-993.
    • (2003) J. Gene Med. , vol.5 , pp. 984-993
    • Harding, C.O.1    Neff, M.2    Jones, K.3    Wild, K.4    Wolff, J.A.5
  • 7
    • 0030729368 scopus 로고    scopus 로고
    • Expression of human phenylalanine hydroxylase activity in T lymphocytes of classical phenylketonuria children by retroviral-mediated gene transfer
    • Lin C M, Tan Y, Lee Y M, Chang C C, Hsiao K J. Expression of human phenylalanine hydroxylase activity in T lymphocytes of classical phenylketonuria children by retroviral-mediated gene transfer. J Inherit Metab Dis 1997: 20: 742-754.
    • (1997) J. Inherit Metab. Dis. , vol.20 , pp. 742-754
    • Lin, C.M.1    Tan, Y.2    Lee, Y.M.3    Chang, C.C.4    Hsiao, K.J.5
  • 8
    • 0026110473 scopus 로고
    • A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes
    • Rosenthal D S, Steinert P M, Chung S et al. A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Growth Differ 1991: 2: 107-113.
    • (1991) Cell Growth Differ. , vol.2 , pp. 107-113
    • Rosenthal, D.S.1    Steinert, P.M.2    Chung, S.3
  • 9
    • 2042527630 scopus 로고
    • Development of an epidermal-specific expression vector for targeting gene expression to the epidermis of transgenic mice
    • Rothnagel J A, Greenhalgh D A, Longley M A, Bundman D, Dominey A M, Roop D R. Development of an epidermal-specific expression vector for targeting gene expression to the epidermis of transgenic mice. J Invest Dermatol 1990: 94: 573.
    • (1990) J. Invest. Dermatol. , vol.94 , pp. 573
    • Rothnagel, J.A.1    Greenhalgh, D.A.2    Longley, M.A.3    Bundman, D.4    Dominey, A.M.5    Roop, D.R.6
  • 10
    • 0031031056 scopus 로고    scopus 로고
    • Transgenic studies with a keratin promoter-driven growth hormone transgene: Prospects for gene therapy
    • Wang X, Zinkel S, Polonsky K, Fuchs E. Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Proc Natl Acad Sci USA 1997: 94: 219-226.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 219-226
    • Wang, X.1    Zinkel, S.2    Polonsky, K.3    Fuchs, E.4
  • 11
    • 17844410918 scopus 로고    scopus 로고
    • A cutaneous gene therapy approach to human leptin deficiencies: Correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts
    • Larcher F, Del Rio M, Serrano F et al. A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts. Faseb J 2001: 15: 1529-1538.
    • (2001) Faseb J. , vol.15 , pp. 1529-1538
    • Larcher, F.1    Del Rio, M.2    Serrano, F.3
  • 12
    • 0034192227 scopus 로고    scopus 로고
    • Correction of the coagulation defect in hemophilia A mice through factor VIII expression in skin
    • Fakharzadeh S S, Zhang Y, Sarkar R, Kazazian H H Jr. Correction of the coagulation defect in hemophilia A mice through factor VIII expression in skin. Blood 2000: 95: 2799-2805.
    • (2000) Blood , vol.95 , pp. 2799-2805
    • Fakharzadeh, S.S.1    Zhang, Y.2    Sarkar, R.3    Kazazian Jr., H.H.4
  • 13
    • 0242270684 scopus 로고    scopus 로고
    • Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis
    • Ellis T, Smyth I, Riley E et al. Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis. Dev Biol 2003: 263: 203-215.
    • (2003) Dev. Biol. , vol.263 , pp. 203-215
    • Ellis, T.1    Smyth, I.2    Riley, E.3
  • 14
    • 0036186833 scopus 로고    scopus 로고
    • Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate
    • Matsumoto T, Jiang J, Kiguchi K et al. Overexpression of a constitutively active form of c-src in skin epidermis increases sensitivity to tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Mol Carcinog 2002: 33: 146-155.
    • (2002) Mol. Carcinog. , vol.33 , pp. 146-155
    • Matsumoto, T.1    Jiang, J.2    Kiguchi, K.3
  • 17
    • 1642502377 scopus 로고    scopus 로고
    • Side population cells in the human and mouse epidermis lack stem cell characteristics
    • Triel C, Vestergaard M E, Bolund L, Jensen T G, Jensen U B. Side population cells in the human and mouse epidermis lack stem cell characteristics. Exp Cell Res 2004: 295: 79-90.
    • (2004) Exp. Cell Res. , vol.295 , pp. 79-90
    • Triel, C.1    Vestergaard, M.E.2    Bolund, L.3    Jensen, T.G.4    Jensen, U.B.5
  • 18
    • 0036392185 scopus 로고    scopus 로고
    • Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria
    • Christensen R, Guttler F, Jensen T G. Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria. Mol Genet Metab 2002: 76: 313-318.
    • (2002) Mol. Genet. Metab. , vol.76 , pp. 313-318
    • Christensen, R.1    Guttler, F.2    Jensen, T.G.3
  • 19
    • 1542560237 scopus 로고
    • Fluorimetric method for the determination of phenylalanine in serum
    • McCaman M, Robins E. Fluorimetric method for the determination of phenylalanine in serum. J Lab Clin Med 1962: 59: 885-890.
    • (1962) J. Lab. Clin. Med. , vol.59 , pp. 885-890
    • McCaman, M.1    Robins, E.2
  • 20
    • 0025988477 scopus 로고
    • Expression of biologically active heterodimeric bovine follicle-stimulating hormone in milk of transgenic mice
    • Greenberg N M, Anderson J W, Hsueh A J et al. Expression of biologically active heterodimeric bovine follicle-stimulating hormone in milk of transgenic mice. Proc Natl Acad Sci USA 1991: 88: 8327-8331.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8327-8331
    • Greenberg, N.M.1    Anderson, J.W.2    Hsueh, A.J.3
  • 21
    • 0026361902 scopus 로고
    • Coinjection strategy for visual identification of transgenic mice
    • Overbeek P A, Aguilar-Cordova E, Hanten G et al. Coinjection strategy for visual identification of transgenic mice. Transgenic Res 1991: 1: 31-37.
    • (1991) Transgenic Res. , vol.1 , pp. 31-37
    • Overbeek, P.A.1    Aguilar-Cordova, E.2    Hanten, G.3
  • 23
    • 0027516110 scopus 로고
    • Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene
    • Greenhalgh D A, Rothnagel J A, Quintanilla M I et al. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog 1993: 7: 99-110.
    • (1993) Mol. Carcinog. , vol.7 , pp. 99-110
    • Greenhalgh, D.A.1    Rothnagel, J.A.2    Quintanilla, M.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.