Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor α

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 24143-24152

  Genolet, Raphael ^a   Kersten, Sander ^a,d   Braissant, Olivier ^b   Mandard, Stéphane ^a,d   Tan, Nguan Soon ^a   Bucher, Philipp ^c   Desvergne, Béatrice ^a   Michalik, Liliane ^a   Wahli, Walter ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BIOSYNTHESIS; ENZYME KINETICS; GENES; GENETIC ENGINEERING; METABOLISM; REDUCTION;

GENE REARRANGEMENTS; GENE REGULATORS; GLYOXYLATE REDUCTASE HYDROXYPYRUVATE REDUCTASE (GRHPR); PLASMA LEVELS;

BIOCHEMISTRY;

GLYOXYLIC ACID; GLYOXYLIC ACID DERIVATIVE; HYDROXYPYRUVATE REDUCTASE; OXALIC ACID; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME REGULATION; GENE; GENE EXPRESSION; GENE REARRANGEMENT; GRHPR GENE; HUMAN; HUMAN CELL; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION;

ALCOHOL OXIDOREDUCTASES; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROXYPYRUVATE REDUCTASE; LIVER; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PPAR ALPHA; PROMOTER REGIONS (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY;

EID: 21244501406     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502649200     Document Type: Article

References (30)

1. Desvergne, B., and Wahli, W. (1999) Endocr. Rev. 20, 649-688
2. Kersten, S., Mandard, S., Escher, P., Gonzalez, F. J., Tafuri, S., Desvergne, B., and Wahli, W. (2001) FASEB J. 15, 1971-1978
3. Shearer, B. G., and Hoekstra, W. J. (2003) Curr. Med. Chem. 10, 267-280
4. Patsouris, D., Mandard, S., Voshol, P. J., Escher, P., Tan, N. S., Havekes, L. M., Koenig, W., Marz, W., Tafuri, S., Wahli, W., Muller, M., and Kersten, S. (2004) J. Clin. Investig. 114, 94-103
5. Mandard, S., Muller, M., and Kersten, S. (2004) Cell Mol. Life Sci. 61, 393-416
6. Holmes, R. P., and Assimos, D. G. (1998) J. Urol. 160, 1617-1624
7. Ogawa, Y., Miyazato, T., and Hatano, T. (2000) World J. Surg. 24, 1154-1159
8. Holmes, R. P., Goodman, H. O., and Assimos, D. G. (2001) Kidney Int. 59, 270-276
9. Leumann, E., and Hoppe, B. (2001) J. Am. Soc. Nephrol. 12, 1986-1993
10. Sharma, V., and Schwille, P. O. (1997) Metabolism 46, 135-139
11. Lee, S. S., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernandez-Salguero, P. M., Westphal, H., and Gonzalez, F. J. (1995) Mol. Cell. Biol. 15, 3012-3022
12. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: α Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
13. Di Poi, N., Tan, N. S., Michalik, L., Wahli, W., and Desvergne, B. (2002) Mol. Cell 10, 721-733
14. Lavery, D. J., Lopez-Molina, L., Pleury-Olela, F., and Schibler, U. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6831-6836
15. Gould, S. J., and Collins, C. S. (2002) Nat. Rev. Mol. Cell. Biol. 3, 382-389
16. Giafi, C. F., and Rumsby, G. (1998) Ann. Clin. Biochem. 35, 104-109
17. Waterston, R. H., Lindblad-Toh, K., Birney, E., Rogers, J., Abril, J. F., Agarwal, P., Agarwala, R., Ainscough, R., Alexandersson, M., An, P., Antonarakis, S. E., Attwood, J., Baertsch, R., Bailey, J., Barlow, K., Beck, S., Berry, E., Birren, B., Bloom, T., Bork, P., Botcherby, M., Bray, N., Brent, M. R., Brown, D. G., Brown, S. D., Bult, C., Burton, J., Butler, J., Campbell, R. D., Carninci, P., Cawley, S., Chiaromonte, F., Chinwalla, A. T., Church, D. M., Clamp, M., Clee, C., Collins, F. S., Cook, L. L., Copley, R. R., Coulson, A., Couronne, O., Cuff, J., Curwen, V., Cutts, T., Daly, M., David, R., Davies, J., Delehaunty, K. D., Deri, J., Dermitzakis, E. T., Dewey, C., Dickens, N. J., Diekhans, M., Dodge, S., Dubchak, I., Dunn, D. M., Eddy, S. R., Elnitski, L., Ernes, R. D., Eswara, P., Eyras, E., Felsenfeld, A., Fewell, G. A., Flicek, P., Foley, K., Frankel, W. N., Fulton, L. A., Fulton, R. S., Furey, T. S., Gage, D., Gibbs, R. A., Glusman, G., Gnerre, S., Goldman, N., Goodstadt, L., Grafham, D., Graves, T. A., Green, E. D., Gregory, S., Guigo, R., Guyer, M., Hardison, R. C., Haussler, D., Hayashizaki, Y., Hillier, L. W., Hinrichs, A., Hlavina, W., Holzer, T., Hsu, F., Hua, A., Hubbard, T., Hunt, A., Jackson, I., Jaffe, D. B., Johnson, L. S., Jones, M., Jones, T. A., Joy, A., Kamal, M., Karlsson, E. K., Karolchik, D., Kasprzyk, A., Kawai, J., Keibler, E., Kells, C., Kent, W. J., Kirby, A., Kolbe, D. L., Korf, I., Kucherlapati, R. S., Kulbokas, E. J., Kulp, D., Landers, T., Leger, J. P., Leonard, S., Letunic, I., Levine, R., Li, J., Li, M., Lloyd, C., Lucas, S., Ma, B., Maglott, D. R., Mardis, E. R., Matthews, L., Mauceli, E., Mayer, J. H., McCarthy, M., McCombie, W. R., McLaren, S., McLay, K., McPherson, J. D., Meldrim, J., Meredith, B., Mesirov, J. P., Miller, W., Miner, T. L., Mongin, E., Montgomery, K. T., Morgan, M., Mott, R., Mullikin, J. C., Muzny, D. M., Nash, W. E., Nelson, J. O., Nhan, M. N., Nicol, R., Ning, Z., Nusbaum, C., O'Connor, M. J., Okazaki, Y., Oliver, K., Overton-Larty, E., Pachter, L., Parra, G., Pepin, K. H., Peterson, J., Pevzner, P., Plumb, R., Pohl, C. S., Poliakov, A., Ponce, T. C., Ponting, C. P., Potter, S., Quail, M., Reymond, A., Roe, B. A., Roskin, K. M., Rubin, E. M., Rust, A. G., Santos, R., Sapojnikov, V., Schultz, B., Schultz, J., Schwartz, M. S., Schwartz, S., Scott, C., Seaman, S., Searle, S., Sharpe, T., Sheridan, A., Shownkeen, R., Sims, S., Singer, J. B., Slater, G., Smit, A., Smith, D. R., Spencer, B., Stabenau, A., Stange-Thomann, N., Sugnet, C., Suyama, M., Tesler, G., Thompson, J., Torrents, D., Trevaskis, E., Tromp, J., Ucla, C., Ureta-Vidal, A., Vinson, J. P., Von Niederhausern, A. C., Wade, C. M., Wall, M., Weber, R. J., Weiss, R. B., Wendl, M. C., West, A. P., Wetterstrand, K., Wheeler, R., Whelan, S., Wierzbowski, J., Willey, D., Williams, S., Wilson, R. K., Winter, E., Worley, K. C., Wyman, D., Yang, S., Yang, S. P., Zdobnov, E. M., Zody, M. C., and Lander, E. S. (2002) Nature 420, 520-562
18. Huang, T., Yang, W., Pereira, A. C., Craigen, W. J., and Shih, V. E. (2000) Biochem. Biophys. Res. Commun. 268, 298-301
19. Podvinec, M., Kaufmann, M. R., Handschin, C., and Meyer, U. A. (2002) Mol. Endocrinol. 16, 1269-1279
20. Mandard, S., Zandbergen, F., Tan, N. S., Escher, P., Patsouris, D., Koenig, W., Kleemann, R., Bakker, A., Veenman, F., Wahli, W., Muller, M., and Kersten, S. (2004) J. Biol. Chem. 279, 34411-34420
21. Kersten, S., Seydoux, J., Peters, J. M., Gonzalez, F. J., Desvergne, B., and Wahli, W. (1999) J. Clin. Investig. 103, 1489-1498
22. Peters, J. M., Rusyn, I., Rose, M. L., Gonzalez, F. J., and Thurman, R. G. (2000) Carcinogenesis 21, 823-826
23. Ogawa, Y., Miyazato, T., Morozumi, M., Sugaya, K., and Hatano, T. (2000) Mol. Urol. 4, 341-348
24. Cramer, S. D., Ferree, P. M., Lin, K., Milliner, D. S., and Holmes, R. P. (1999) Hum. Mol. Genet. 8, 2063-2069
25. Michalik, L., Desvergne, B., and Wahli, W. (2004) Nat. Rev. Cancer 4, 61-70
26. Lambe, K. G., Woodyatt, N. J., Macdonald, N., Chevalier, S., and Roberts, R. A. (1999) Toxicol. Lett. 110, 119-127
27. Vu-Dac, N., Chopin-Delannoy, S., Gervois, P., Bonnelye, E., Martin, G., Fruchart, J. C., Laudet, V., and Staels, B. (1998) J. Biol. Chem. 273, 25713-25720
28. Tagle, D. A., Koop, B. F., Goodman, M., Slightom, J. L., Hess, D. L., and Jones, R. T. (1988) J. Mol. Biol. 203, 439-455
29. Wu, P., Peters, J. M., and Harris, R. A. (2001) Biochem. Biophys. Res. Commun. 287, 391-396
30. Xu, J., Xiao, G., Trujillo, C., Chang, V., Blanco, L., Joseph, S. B., Bassilian, S., Saad, M. F., Tontonoz, P., Lee, W. N., and Kurland, I. J. (2002) J. Biol. Chem. 277, 50237-50244