Neural adhesion molecules L1 and CHL1 are survival factors for motoneurons

Journal of Neuroscience Research

Volumn 80, Issue 5, 2005, Pages 593-599

  Nishimune, H ^a   Bernreuther, C ^b   Carroll, P ^a   Chen, S ^b   Schachner, M ^b   Henderson, C E ^a,c  

^a INSERM   (France)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Neurotrophic; PI3 kinase; Survival pathways

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; HYBRID PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; NERVE CELL ADHESION MOLECULE CHL1; NERVE CELL ADHESION MOLECULE L1; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CELL CULTURE; CELL SURVIVAL; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; IN SITU HYBRIDIZATION; IN VIVO STUDY; MOTONEURON; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL ADHESION MOLECULES; CELL SURVIVAL; CELLS, CULTURED; CHO CELLS; CRICETINAE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LEUKOCYTE L1 ANTIGEN COMPLEX; MAP KINASE SIGNALING SYSTEM; MICE; MOTOR NEURONS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT FUSION PROTEINS; SPINAL CORD;

EID: 21244494438     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20517     Document Type: Article

References (46)

1. Arakawa Y, Sendtner M, Thoenen H. 1990. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci 10:3507-3515.
2. Arce V, Garces A, de Bovis B, Filippi P, Henderson C, Pettmann B, deLapeyrière O. 1999. Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique. J Neurosci Res 55:119-126.
3. Bagnard D, Vaillant C, Khuth ST, Dufay N, Lohrum M, Puschel AW, Belin MF, Bolz J, Thomasset N. 2001. Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor. J Neurosci 21:3332-3341.
4. Brummendorf T, Kenwrick S, Rathjen FG. 1998. Neural cell recognition molecule L1: from cell biology to human hereditary brain malformations. Curr Opin Neurobiol 8:87-97.
5. Burden-Gulley SM, Pendergast M, Lemmon V. 1997. The role of cell adhesion molecule L1 in axonal extension, growth cone motility, and signal transduction. Cell Tissue Res 290:415-422.
6. Castellani V, Chedotal A, Schachner M, Faivre-Sarrailh C, Rougon G. 2000. Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron 27:237-249.
7. Chen S, Mantei N, Dong L, Schachner M. 1999. Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1. J Neurobiol 38:428-439.
8. deLapeyrière O, Henderson CE. 1997. Motoneuron differentiation, survival and synaptogenesis. Curr Opin Genet Dev 7:642-650.
9. Doherty P, Williams G, Williams EJ. 2000. CAMs and axonal growth: a critical evaluation of the role of calcium and the MAPK cascade. Mol Cell Neurosci 16:283-295.
10. Eichberg J. 2002. Myelin PO: new knowledge and new roles. Neurochem Res 27:1331-1340.
11. Gagliardini V, Fankhauser C. 1999. Semaphorin III can induce death in sensory neurons. Mol Cell Neurosci 14:301-316.
12. Garces A, Haase G, Airaksinen MS, Livet J, Filippi P, deLapeyrière O. 2000a. GFRalpha 1 is required for development of distinct subpopulations of motoneuron. J Neurosci 20:4992-5000.
13. Garces A, Nishimune H, Philippe JM, Pettmami B, deLapeyrière O. 2000b. FGF9: a motoneuron survival factor expressed by medial thoracic and sacral motoneurons. J Neurosci Res 60:1-9.
14. Gouin A, Bloch-Gallego E, Tanaka H, Rosenthal A, Henderson CE. 1996. Transforming growth factor-beta 3, glial cell line-derived neurotrophic factor, and fibroblast growth factor-2, act in different manners to promote motoneuron survival in vitro. J Neurosci Res 43:454-464.
15. Could TW, Oppenheim RW. 2004. The function of neurotrophic factor receptors expressed by the developing adductor motor pool in vivo. J Neurosci 24:4668-4682.
16. Grothe C, Unsicker K. 1992. Basic fibroblast growth factor in the hypoglossal system: specific retrograde transport, trophic, and lesion-related responses. J Neurosci Res 32:317-328.
17. Henderson CE. 1996. Role of neurotrophic factors in neuronal development. Curr Opin Neurobiol 6:64-70.
18. Henderson CE, Camu W, Metding C, Gouin A, Poulsen K, Karihaloo M, Rullamas J, Evans T, McMahon SB, Armanini MP, Berkemeier L, Phillips HS, Rosenthal A. 1993. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363:266-270.
19. Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, Simpson LC, Moffet B, Vandlen RA, Koliatsos VE, Rosenthal A. 1994. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science 266:1062-1064.
20. Henderson CE, Bloch-Gallego E, Camu W. 1995. Purified embryonic motoneurons. In: Cohen J, Wilkin G, editors. Nerve cell culture: a practical approach. London: Oxford University Press, p 69-81.
21. Hillenbrand R, Molthagen M, Montag D, Schachner M. 1999. The close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactions. Eur J Neurosci 11:813-826.
22. Hortsch M. 2000. Structural and functional evolution of the L1 family: are four adhesion molecules better than one? Mol Cell Neurosci 15: 1-10.
23. Hulley P, Schachner M, Lubbert H. 1998. L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons. J Neurosci Res 53:129-134.
24. Kahane N, Shelton DL, Kalcheim C. 1996. Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets. J Neurobiol 29:277-292.
25. Kalus I, Schnegelsberg B, Seidah NG, Kleene R, Schachner M. 2003. The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1. J Biol Chem 278:10381-10388.
26. Kamiguchi H, Hlavin ML, Lemmon V. 1998. Role of L1 in neural development: what the knockouts tell us. Mol Cell Neurosci 12:48-55.
27. Kaplan DR, Miller FD. 2000. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10:381-391.
28. Kleene R, Yang H, Kutsche M, Schachner M. 2001. The neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowth. J Biol Chem 276:21656-21663.
29. Landmesser L, Dahm L, Schultz K, Rutishauser U. 1988. Distinct roles for adhesion molecules during innervation of embryonic chick muscle. Dev Biol 130:645-670.
30. Landmesser L, Dahm L, Tang JC, Rutishauser U. 1990. Polysialic acid as a regulator of intramuscular nerve branching during embryonic development. Neuron 4:655-667.
31. Lentz SI, Knudson CM, Korsmeyer SJ, Snider WD. 1999. Neurotrophins support the development of diverse sensory axon morphologies. J Neurosci 19:1038-1048.
32. Naus S, Richter M, Wildeboer D, Moss M, Schachner M, Bartsch JW. 2004. Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death. J Biol Chem 279:16083-16090.
33. Nishimune H, Vasseur S, Wiese S, Birling MC, Holtmann B, Sendtner M, Iovanna JL, Henderson CE. 2000. Reg-2 is a motoneuron neurotrophic factor and a signaling intermediate in the CNTF survival pathway. Nat Cell Biol 2:906-914.
34. Oppenheim RW. 1991. Cell death during development of the nervous system. Annu Rev Neurosci 14:453-501.
35. Oppenheim RW. 1996. Neurotrophic survival molecules for motoneurons: an embarrassment of riches. Neuron 17:195-197.
36. Patel TD, Jackman A, Rice FL, Kucera J, Snider WD. 2000. Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. Neuron 25:345-357.
37. Peters KG, Werner S, Chen G, Williams LT. 1992. Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development 114:233-243.
38. Pettmann B, Henderson CE. 1998. Neuronal cell death. Neuron 20:633-647.
39. Saffell JL, Williams EJ, Mason IJ, Walsh FS, Doherty P. 1997. Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron 18:231-242.
40. Sendtner M, Gotz R, Holtmann B, Thoenen H. 1997. Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. J Neurosci 17:6999-7006.
41. Shirvan A, Ziv I, Fleminger G, Shina R, He Z, Brudo I, Melamed E, Barzilai A. 1999. Semaphorins as mediators of neuronal apoptosis. J Neurochem 73:961-971.
42. Tucker KL, Meyer M, Barde YA. 2001. Neurotrophins are required for nerve growth during development. Nat Neurosci 4:29-37.
43. Unsicker K, Reichert-Preibsch H, Schmidt R, Pettmann B, Labourdette G, Sensenbrenner M. 1987. Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc Natl Acad Sci U S A 84:5459-5463.
44. Vutskits L, Djebbara-Hannas Z, Zhang H, Paccaud JP, Durbec P, Rougon G, Muller D, Kiss JZ. 2001. PSA-NCAM modulates BDNF-dependent survival and differentiation of cortical neurons. Eur J Neurosci 13:1391-1402.
45. Walsh FS, Doherty P. 1997. Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annu Rev Cell Dev Biol 13:425-456.
46. Zhang Y, Roslan R, Lang D, Schachner M, Lieberman AR, Anderson PN. 2000. Expression of CHL1 and L1 by neurons and glia following sciatic nerve and dorsal root injury. Mol Cell Neurosci 16:71-86.