Exosite-mediated substrate recognition of factor IX by factor XIa: The factor XIa heavy chain is required for initial recognition of factor IX

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 23523-23530

  Ogawa, Taketoshi ^a   Verhamme, Ingrid M ^a   Sun, Mao Fu ^a   Bock, Paul E ^a   Gailani, David ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; BLOOD; CATALYSIS; COAGULATION; ENZYME INHIBITION; ENZYMES; NITROGEN COMPOUNDS;

APROTININ; BLOOD COAGULATION; EXOSITE INTERACTIONS; PROTEASE;

BIOCHEMISTRY;

4 AMINOBENZAMIDINE; APROTININ; BLOOD CLOTTING FACTOR 11A; BLOOD CLOTTING FACTOR 9; CHROMOGENIC SUBSTRATE; TRIPEPTIDE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HYDROLYSIS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APROTININ; BENZAMIDINES; CATALYSIS; CATALYTIC DOMAIN; FACTOR IX; FACTOR XIA; HUMANS; HYDROLYSIS; SUBSTRATE SPECIFICITY;

EID: 21244476861     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500894200     Document Type: Article

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