Induction of connective tissue growth factor expression by sphingosylphosphorylcholine in cultured human skin fibroblasts

Experimental Dermatology

Volumn 14, Issue 7, 2005, Pages 509-514

  Zhu, Ming Ji ^a,b   Kim, Chang Deok ^a   Kwon, Yoo Bin ^a   Kye, Kyung Chae ^a   Chen, Yuan Yao ^b   Lee, Woong Hee ^a   Lee, Sangkeun ^c   Lim, Jong Soon ^c   Seo, Young Joon ^a   Suhr, Ki Beom ^a   Park, Jang Kyu ^a   Lee, Jeung Hoon ^a  

^a Chungnam National University   (South Korea)

^b JILIN UNIVERSITY   (China)

^c Daejeon University   (South Korea)

Author keywords

Connective tissue growth factor; Rho kinase; Skin fibroblasts; Sphingosylphosphorylcholine

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CONNECTIVE TISSUE GROWTH FACTOR; CYCLOHEXIMIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATASE; PHOSPHATE TRANSPORTER; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE; REGULATOR PROTEIN; SPHINGOSYLPHOSPHORYLCHOLINE;

ARTICLE; CELL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MICROARRAY; PROTEIN SYNTHESIS; TIME; WESTERN BLOTTING; WOUND HEALING;

BASE SEQUENCE; CELLS, CULTURED; DNA, COMPLEMENTARY; FIBROBLASTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLCHOLINE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN; SPHINGOSINE;

EID: 21244465921     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2005.00310.x     Document Type: Article

References (36)

1. Higuchi K, Kawashima M, Takagi Y et al. Sphingosyl phosphorylcholine is an activator of transglutaminase activity in human keratinocytes. J Lipid Res 2001: 42: 1562-1570.
2. Boguslawski G, Lyons D, Harvey K A, Kovala A T, English D. Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis. Biochem Biophys Res Commun 2000: 272: 603-609.
3. Boguslawski G, Grogg J R, Welch Z et al. Migration of vascular smooth muscle cells induced by sphingosine 1-phosphate and related lipids: potential role in the angiogenic response. Exp Cell Res 2002: 274: 264-274.
4. Spiegel S, Milstien S. Sphingolipid metabolites: members of a new class of lipid second messengers. J Membr Biol 1995: 146: 225-237.
5. Zanglis A, Lianos E A, Demopoulos C A. The biological activity of acetylated sphingosylphosphorylcholine derivatives. Int J Biochem Cell Biol 1996: 28: 63-74.
6. Desai N N, Spiegel S. Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines. Biochem Biophys Res Commun 1991: 181: 361-366.
7. Sun L, Xu L, Henry F A, Spiegel S, Nielsen T B. A new wound healing agent-sphingosylphosphorylcholine. J Invest Dermatol 1996: 106: 232-237.
8. + mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells. J Biol Chem 1995: 270: 26332-26340.
9. Seufferlein T, Rozengurt E. Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein. J Biol Chem 1995: 270: 24334-24342.
10. Meyer zu Heringdorf D, Niederdraing N, Neumann E et al. Discrimination between plasma membrane and intracellular target sites of Sphingosylphosphorylcholine. Eur J Pharmacol 1998: 354: 113-122.
11. Xu Y, Zhu K, Hong G et al. Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1. Nat Cell Biol 2000: 2: 261-267.
12. +-dependent pathway. Am J Physiol 1998: 275: C1255-C1263.
13. Wakita H, Matsushita K, Nishimura K, Tokura Y, Furukawa F, Takigawa M. Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. J Invest Dermatol 1998: 110: 253-258.
14. Suhr K B, Tsuboi R, Ogawa H. Sphingosylphosphorylcholine stimulates contraction of fibroblast-embedded collagen gel. Br J Dermatol 2000: 143: 66-71.
15. Suhr K B, Tsuboi R, Seo E Y et al. Sphingosylphosphorylcholine stimulates cellular fibronectin expression through upregulation of IL-6 in cultured human dermal fibroblasts. Arch Dermatol Res 2003: 294: 433-437.
16. Kye K C, Chae E K, Piao Y J et al. Signaling events during induction of plasminogen activator inhibitor-1 expression by sphingosylphosphorylcholine in cultured human dermal fibroblasts. J Invest Dermatol 2004: 122: 1365-1371.
17. Bradham D M, Igarashi A, Potter R L, Grotendorst G R. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 1991: 114: 1285-1294.
18. Wang J F, Olson M E, Ball D K, Brigstock D R, Hart D A. Recombinant connective tissue growth factor modulates porcine skin fibroblast gene expression. Wound Repair Regen 2003: 11: 220-229.
19. Chen C C, Chen N, Lau L F. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. J Biol Chem 2001: 276: 10443-10452.
20. Igarashi A, Okochi H, Bradham D M, Grotendorst G R. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 1993: 4: 637-645.
21. Yang S H, Kim J S, Oh T J et al. Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA micro-array. Int J Oncol 2003: 22: 741-750.
22. Zhu K, Baudhuin L M, Hong G et al. Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4. J Biol Chem 2001: 276: 41325-41335.
23. Liscovitch M, Cantley L C. Lipid second messengers. Cell 1994: 77: 329-334.
24. Igarashi A, Nashiro K, Kikuchi K et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 1996: 106: 729-733.
25. Grotendorst G R. Connective tissue growth factor: a mediator of TGF-β action on fibroblasts. Cytokine Growth Factor Rev 1997: 8: 171-179.
26. Roberts A B, Sporn M B. Physiological actions and clinical applications of transforming growth factor-β (TGF-β). Growth Factors 1993: 8: 1-9.
27. O'Kane S, Ferguson M W. Transforming growth factor βs and wound healing. Int J Biochem Cell Biol 1997: 29: 63-78.
28. Verrecchia F, Mauviel A. Transforming growth factor-β signaling through the Smad pathway: role in extracellular matrix gene expression and regulation. J Invest Dermatol 2002: 118: 211-215.
29. Duncan M R, Frazier K S, Abramson S et al. Connective tissue growth factor mediates transforming growth factor-β-induced collagen synthesis: down-regulation by camp. FASEB J 1999: 13: 1774-1786.
30. Daniels J T, Schultz G S, Blalock T D et al. Mediation of transforming growth factor-β (1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring. Am J Pathol 2003: 163: 2043-2052.
31. Olivera A, Spiegel S. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 1993: 365: 557-560.
32. Mattie M, Brooker G, Spiegel S. Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J Biol Chem 1994: 269: 3181-3188.
33. Spiegel S. Sphingosine 1-phosphate: a prototype of a new class of second messengers. J Leukoc Biol 1999: 65: 341-344.
34. Bektas M, Barak L S, Jolly P S et al. The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner. Biochemistry 2003: 42: 12181-12191.
35. Heusinger-Ribeiro J, Eberlein M, Wahab N A, Goppelt-Struebe M. Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and camp. J Am Soc Nephrol 2001: 12: 1853-1861.
36. Kranenburg O, Poland M, van Horck F P, Drechsel D, Hall A, Moolenaar W H. Activation of RhoA by lysophosphatidic acid and Ga12/13 subunits in neuronal cells: induction of neurite retraction. Mol Biol Cell 1999: 10: 1851-1857.