메뉴 건너뛰기




Volumn 29, Issue 1, 1997, Pages 63-78

Transforming growth factor βs and wound healing

Author keywords

Chronic wounds; Fibrosis; Scarring; TGF s; Wound healing

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; CYTOKINE; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031016797     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(96)00120-3     Document Type: Review
Times cited : (585)

References (131)
  • 1
    • 0028953810 scopus 로고
    • Transforming growth-factor-β and cell-cycle regulation
    • Alexandrow M. G. and Moses H. L. (1995) Transforming growth-factor-β and cell-cycle regulation. Cancer Res. 55, 1452-1457.
    • (1995) Cancer Res. , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 2
    • 0029154515 scopus 로고
    • The effects of ageing on cutaneous wound healing in mammals
    • Ashcroft G. S., Horan M. A. and Ferguson M. W. J. (1995) The effects of ageing on cutaneous wound healing in mammals. J. Anat. 187, 1-26.
    • (1995) J. Anat. , vol.187 , pp. 1-26
    • Ashcroft, G.S.1    Horan, M.A.2    Ferguson, M.W.J.3
  • 3
    • 4243993084 scopus 로고
    • Redox mediated latent TGF-β activation
    • Barcellos-Hoff M. H. (1995) Redox mediated latent TGF-β activation. Faseb J. 9, A125.
    • (1995) Faseb J. , vol.9
    • Barcellos-Hoff, M.H.1
  • 5
    • 0027141118 scopus 로고
    • One systemic administration of transforming growth factor-β reverses age-or glucocorticoid-impaired wound healing
    • Beck L. S., DeGuzman L., Lee W. P., Xu Y., Siegel M. W. and Amento E. P. (1993) One systemic administration of transforming growth factor-β reverses age-or glucocorticoid-impaired wound healing. J. Clin. Invest. 92, 2841-2849.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2841-2849
    • Beck, L.S.1    Deguzman, L.2    Lee, W.P.3    Xu, Y.4    Siegel, M.W.5    Amento, E.P.6
  • 8
    • 0027375770 scopus 로고
    • Transforming growth factor-β1 enhances glomerular collagen synthesis in diabetic rats
    • Bollineni J. S. and Reddi A. S. (1993) Transforming growth factor-β1 enhances glomerular collagen synthesis in diabetic rats. Diabetes 42, 1673-1677.
    • (1993) Diabetes , vol.42 , pp. 1673-1677
    • Bollineni, J.S.1    Reddi, A.S.2
  • 9
    • 0025277164 scopus 로고
    • Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1
    • Border W. A., Okuda S., Languino L. R., Sporn M. B. and Rouslahti E. (1990) Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1. Nature 346, 371-374.
    • (1990) Nature , vol.346 , pp. 371-374
    • Border, W.A.1    Okuda, S.2    Languino, L.R.3    Sporn, M.B.4    Rouslahti, E.5
  • 10
    • 0028109801 scopus 로고
    • Transforming growth factor β in tissue fibrosis
    • Border W. A. and Noble N. A. (1994) Transforming growth factor β in tissue fibrosis. N. Engl. J. Med. 331, 1286-1292.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 12
    • 0026010305 scopus 로고
    • Transforming growth factor β1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
    • Broekelmann T. J., Limper A. H., Colby T. V. and McDonald J. A. (1991) Transforming growth factor β1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl Acad. Sci. U.S.A. 88, 6642-6646.
    • (1991) Proc. Natl Acad. Sci. U.S.A. , vol.88 , pp. 6642-6646
    • Broekelmann, T.J.1    Limper, A.H.2    Colby, T.V.3    McDonald, J.A.4
  • 14
    • 0023695088 scopus 로고
    • Heterodimeric transforming growth factor β; biological properties and interaction with three types of cell surface receptors
    • Cheifetz S., Bassols A., Stanley K., Ohta M., Greenberger J. and Massagué J. (1988) Heterodimeric transforming growth factor β; biological properties and interaction with three types of cell surface receptors. J. biol. Chem. 263, 10783-10789.
    • (1988) J. Biol. Chem. , vol.263 , pp. 10783-10789
    • Cheifetz, S.1    Bassols, A.2    Stanley, K.3    Ohta, M.4    Greenberger, J.5    Massagué, J.6
  • 15
    • 0011285789 scopus 로고    scopus 로고
    • Do it all protein helps kidney repair
    • Coghlan A, (1996) Do it all protein helps kidney repair. New Scientist 150, 2031, 25.
    • (1996) New Scientist , vol.150 , pp. 25
    • Coghlan, A.1
  • 17
    • 0028222602 scopus 로고
    • Immunohistochemical localization of transforming growth factor-β1 in the lungs of patients with systemic sclerosis, cryptogenic fibrosing alveolitis and other lung disorders
    • Corrin B., Butcher D., McAnulty R. J., du Bois R. M., Black C. M., Laurent G. J. and Harrison N. K. (1994) Immunohistochemical localization of transforming growth factor-β1 in the lungs of patients with systemic sclerosis, cryptogenic fibrosing alveolitis and other lung disorders. Histopathology 24, 145-150.
    • (1994) Histopathology , vol.24 , pp. 145-150
    • Corrin, B.1    Butcher, D.2    McAnulty, R.J.3    Du Bois, R.M.4    Black, C.M.5    Laurent, G.J.6    Harrison, N.K.7
  • 18
    • 0026465895 scopus 로고
    • Wound healing in aged animals: Effect of locally applied TGF-β2 in different model systems
    • Eds Steiner R., Weisz P. B. and Langer R., Birkhauser. Basel
    • Cox D. A., Kunz S., Cerletti N., McMaster G. K. and Burk R. R. (1992) Wound healing in aged animals: effect of locally applied TGF-β2 in different model systems. In Angiogenesis - Key Principles (Eds Steiner R., Weisz P. B. and Langer R.), pp. 287-295. Birkhauser. Basel.
    • (1992) Angiogenesis - Key Principles , pp. 287-295
    • Cox, D.A.1    Kunz, S.2    Cerletti, N.3    McMaster, G.K.4    Burk, R.R.5
  • 19
    • 0025238475 scopus 로고
    • Differential inhibition of transforming growth factor β1 and β2 activity by α2-macroglobulin
    • Danielpour D. and Sporn M. B. (1990) Differential inhibition of transforming growth factor β1 and β2 activity by α2-macroglobulin. J. biol. Chem. 265, 6973-6977.
    • (1990) J. Biol. Chem. , vol.265 , pp. 6973-6977
    • Danielpour, D.1    Sporn, M.B.2
  • 20
    • 0027978411 scopus 로고
    • Neutralization of transforming growth factor β1 in a mouse model of immune-induced lung fibrosis
    • Denis M. (1994) Neutralization of transforming growth factor β1 in a mouse model of immune-induced lung fibrosis. Immunology 82, 584-590.
    • (1994) Immunology , vol.82 , pp. 584-590
    • Denis, M.1
  • 21
    • 0026059613 scopus 로고
    • Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate insulin-like growth-factor type-II receptor
    • Dennis P. A. and Rifkin D. B. (1991) Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate insulin-like growth-factor type-II receptor. Proc. Natl Acad. Sci. U.S.A. 88, 580-584.
    • (1991) Proc. Natl Acad. Sci. U.S.A. , vol.88 , pp. 580-584
    • Dennis, P.A.1    Rifkin, D.B.2
  • 22
    • 0028173316 scopus 로고
    • TGF-β-receptor-mediated signalling
    • Derynck R. (1994) TGF-β-receptor-mediated signalling. Trends Biochem. Sci. 19, 548-553.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 548-553
    • Derynck, R.1
  • 23
    • 0028906190 scopus 로고
    • Processing of transforming growth-factor-β-1 precursor by human furin convertase
    • DuBois C. M., Laprise M. H., Blanchette F., Gentry L. E. and Leduc R. (1995) Processing of transforming growth-factor-β-1 precursor by human furin convertase. J. biol. Chem. 270, 10618-10624.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10618-10624
    • Dubois, C.M.1    Laprise, M.H.2    Blanchette, F.3    Gentry, L.E.4    Leduc, R.5
  • 24
    • 0029883757 scopus 로고    scopus 로고
    • Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern
    • Fajardo L. F., Prionas S. D., Kwan H. H., Kowalski J. and Allison A. C. (1996) Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern. Lab. Invest. 74, 600-608.
    • (1996) Lab. Invest. , vol.74 , pp. 600-608
    • Fajardo, L.F.1    Prionas, S.D.2    Kwan, H.H.3    Kowalski, J.4    Allison, A.C.5
  • 25
    • 0028972072 scopus 로고
    • Transforming growth factor β (TGFβ) -induced downregulation of cyclin-a expression requires a functional TGFβ receptor complex - Characterization of chimeric and truncated type I and type II receptors
    • Feng X.-H., Filvaroff E. H. and Derynck R. (1995) Transforming growth factor β (TGFβ) -induced downregulation of cyclin-A expression requires a functional TGFβ receptor complex - characterization of chimeric and truncated type I and type II receptors. J. biol. Chem. 270, 24237-24245.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24237-24245
    • Feng, X.-H.1    Filvaroff, E.H.2    Derynck, R.3
  • 27
    • 0029875396 scopus 로고    scopus 로고
    • Transforming growth factors β1, β2 and β3 and their receptors are differentially regulated during normal and impaired wound healing
    • Frank S., Madlener M. and Werner S. (1996) Transforming growth factors β1, β2 and β3 and their receptors are differentially regulated during normal and impaired wound healing. J. biol. Chem. 271, 10188-10193.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10188-10193
    • Frank, S.1    Madlener, M.2    Werner, S.3
  • 28
    • 0027425864 scopus 로고
    • Effect of antibody to transforming growth factor β on bleomycin induced accumulation of lung collagen in mice
    • Giri S. N., Hyde D. M. and Hollinger M. A. (1993) Effect of antibody to transforming growth factor β on bleomycin induced accumulation of lung collagen in mice. Thorax 48, 959-966.
    • (1993) Thorax , vol.48 , pp. 959-966
    • Giri, S.N.1    Hyde, D.M.2    Hollinger, M.A.3
  • 29
    • 0026750620 scopus 로고
    • Transforming growth factor-beta 2 for the treatment of full thickness macular holes. A prospective randomized study
    • Glaser B. M., Michels R. G., Kuppermann B. D., Sjaarda R. N. and Pena R. A. (1992) Transforming growth factor-beta 2 for the treatment of full thickness macular holes. A prospective randomized study. Ophthalmology 99, 1162-1172.
    • (1992) Ophthalmology , vol.99 , pp. 1162-1172
    • Glaser, B.M.1    Michels, R.G.2    Kuppermann, B.D.3    Sjaarda, R.N.4    Pena, R.A.5
  • 30
    • 0029940972 scopus 로고    scopus 로고
    • Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily
    • Graff J. M., Bansal A. and Melton D. A. (1996) Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily. Cell 85, 479-487.
    • (1996) Cell , vol.85 , pp. 479-487
    • Graff, J.M.1    Bansal, A.2    Melton, D.A.3
  • 31
    • 0029898731 scopus 로고    scopus 로고
    • Tamoxifen: Teaching an old dog new tricks?
    • Grainger D. J. and Metcalfe J. C. (1996) Tamoxifen: teaching an old dog new tricks? Nature Med. 2, 381-385.
    • (1996) Nature Med. , vol.2 , pp. 381-385
    • Grainger, D.J.1    Metcalfe, J.C.2
  • 33
    • 0029029807 scopus 로고
    • Release and activation of platelet latent TGFβ in blood clots during dissolution with plasmin
    • Grainger D. J., Wakefield L., Bethell H. W., Farndale R. W. and Metcalfe J. C. (1995b) Release and activation of platelet latent TGFβ in blood clots during dissolution with plasmin. Nature Med. 1, 932-937.
    • (1995) Nature Med. , vol.1 , pp. 932-937
    • Grainger, D.J.1    Wakefield, L.2    Bethell, H.W.3    Farndale, R.W.4    Metcalfe, J.C.5
  • 35
    • 0027017351 scopus 로고
    • Control of transforming growth factor beta activity: Latency vs. activation
    • Harpel J. G., Metz C. N., Kojima S. and Rifkin D. B. (1992) Control of transforming growth factor beta activity: latency vs. activation. Prog. Growth Factor Res. 4, 321-335.
    • (1992) Prog. Growth Factor Res. , vol.4 , pp. 321-335
    • Harpel, J.G.1    Metz, C.N.2    Kojima, S.3    Rifkin, D.B.4
  • 36
    • 0026437639 scopus 로고
    • Sequential-changes in histologic pattern and extracellular-matrix deposition during the healing of chronic venous ulcers
    • Herrick S. E., Sloan P., McGurk M., Freak L., McCollum C. N. and Ferguson M. W. J. (1992) Sequential-changes in histologic pattern and extracellular-matrix deposition during the healing of chronic venous ulcers. Am. J. Pathol. 141, 1085-1095.
    • (1992) Am. J. Pathol. , vol.141 , pp. 1085-1095
    • Herrick, S.E.1    Sloan, P.2    McGurk, M.3    Freak, L.4    McCollum, C.N.5    Ferguson, M.W.J.6
  • 37
    • 0028948764 scopus 로고
    • Extravasation of macromolecules and possible trapping of transforming growth factor-β in venous ulceration
    • Higley H. R., Ksander G. A., Gerhardt C. O. and Falanga V. (1995) Extravasation of macromolecules and possible trapping of transforming growth factor-β in venous ulceration. Br. J. Dermatol. 132, 79-85.
    • (1995) Br. J. Dermatol. , vol.132 , pp. 79-85
    • Higley, H.R.1    Ksander, G.A.2    Gerhardt, C.O.3    Falanga, V.4
  • 38
    • 0027984873 scopus 로고
    • Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta
    • Hildebrand A., Romans M., Rasmussen L. M., Heinegard D., Twardzik D., Border W. A. and Rouslahti E. (1994) Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta. Biochem. J. 303, 527-534.
    • (1994) Biochem. J. , vol.303 , pp. 527-534
    • Hildebrand, A.1    Romans, M.2    Rasmussen, L.M.3    Heinegard, D.4    Twardzik, D.5    Border, W.A.6    Rouslahti, E.7
  • 40
    • 0023712356 scopus 로고
    • Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-β precede bleomycin-induced pulmonary fibrosis in mice
    • Hoyt D. G. and Lazo J. S. (1988) Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-β precede bleomycin-induced pulmonary fibrosis in mice. J. Pharmacol. Exp. Ther. 246, 765-771.
    • (1988) J. Pharmacol. Exp. Ther. , vol.246 , pp. 765-771
    • Hoyt, D.G.1    Lazo, J.S.2
  • 41
    • 0342902626 scopus 로고    scopus 로고
    • Strong induction of activin expression after injury suggests an important role of activin in wound repair
    • Hubner G., Hu Q., Smola H. and Werner S. (1996) Strong induction of activin expression after injury suggests an important role of activin in wound repair. Dev. Biol. 173, 490-498.
    • (1996) Dev. Biol. , vol.173 , pp. 490-498
    • Hubner, G.1    Hu, Q.2    Smola, H.3    Werner, S.4
  • 42
    • 0029905441 scopus 로고    scopus 로고
    • Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
    • Isaka Y., Brees D. K., Ikegaya K., Kaneda Y., Imai E., Noble N. A. and Border W. A. (1996) Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nature Med. 2, 418-423.
    • (1996) Nature Med. , vol.2 , pp. 418-423
    • Isaka, Y.1    Brees, D.K.2    Ikegaya, K.3    Kaneda, Y.4    Imai, E.5    Noble, N.A.6    Border, W.A.7
  • 43
    • 0027373251 scopus 로고
    • Regulation of the levels of 3 transforming growth factor beta messenger RNAs by estrogen and their effects on the proliferation of human breast cancer cells
    • Jeng M. H., TenDijke P., Iwata K. K. and Jordan V. C. (1993) Regulation of the levels of 3 transforming growth factor beta messenger RNAs by estrogen and their effects on the proliferation of human breast cancer cells. Mol. Cell. Endocrinol. 97, 115-123.
    • (1993) Mol. Cell. Endocrinol. , vol.97 , pp. 115-123
    • Jeng, M.H.1    Tendijke, P.2    Iwata, K.K.3    Jordan, V.C.4
  • 45
    • 0028362076 scopus 로고
    • Angiotensin-II stimulates extracellular-matrix protein-synthesis through induction of transforming growth-factor beta expression in rat glomerular mesangial cells
    • Kagami S., Border W. A., Miller D. E. and Noble N. A. (1994) Angiotensin-II stimulates extracellular-matrix protein-synthesis through induction of transforming growth-factor beta expression in rat glomerular mesangial cells. J. Clin. Invest. 93, 2431-2437.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2431-2437
    • Kagami, S.1    Border, W.A.2    Miller, D.E.3    Noble, N.A.4
  • 46
    • 0025830392 scopus 로고
    • Direct evidence for spatial and temporal regulation of transforming growth factor β1 expression during cutaneous wound healing
    • Kane C. J., Hebda P. A., Mansbridge J. N. and Hanawalt P. C. (1991) Direct evidence for spatial and temporal regulation of transforming growth factor β1 expression during cutaneous wound healing. J. Cell Physiol. 148, 157-173.
    • (1991) J. Cell Physiol. , vol.148 , pp. 157-173
    • Kane, C.J.1    Hebda, P.A.2    Mansbridge, J.N.3    Hanawalt, P.C.4
  • 48
    • 0030076509 scopus 로고    scopus 로고
    • TGF-β1 but not TGF-β2 or TGF-β3 is differentially present in epithelial cells of advanced pulmonary fibrosis-an immunohistochemical study
    • Khalil N., O'Connor R. N., Flanders K. C. and Unruh H. (1996) TGF-β1 but not TGF-β2 or TGF-β3 is differentially present in epithelial cells of advanced pulmonary fibrosis-an immunohistochemical study. Am. J. Resp. Cell. Mol. Biol. 14, 131-138.
    • (1996) Am. J. Resp. Cell. Mol. Biol. , vol.14 , pp. 131-138
    • Khalil, N.1    O'Connor, R.N.2    Flanders, K.C.3    Unruh, H.4
  • 49
    • 0028180315 scopus 로고
    • The TGF-β superfamily: New members, new receptors and new genetic tests of function in different organisms
    • Kingsley D. M. (1994a) The TGF-β superfamily: new members, new receptors and new genetic tests of function in different organisms. Genes Dev. 8, 133-146.
    • (1994) Genes Dev. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 50
    • 0027976891 scopus 로고
    • What do BMPs do in mammals? clues form the short-ear mutation
    • Kingsley D. M. (1994b) What do BMPs do in mammals? Clues form the short-ear mutation. Trends Genet. 10, 16-21.
    • (1994) Trends Genet. , vol.10 , pp. 16-21
    • Kingsley, D.M.1
  • 51
    • 0027298030 scopus 로고
    • Mechanism of retinoid-induced activation of latent transforming growth factor-beta in bovine endothelial cells
    • Kojima S. and Rifkin D. B. (1993) Mechanism of retinoid-induced activation of latent transforming growth factor-beta in bovine endothelial cells. J. Cell Physiol. 155, 323-332.
    • (1993) J. Cell Physiol. , vol.155 , pp. 323-332
    • Kojima, S.1    Rifkin, D.B.2
  • 54
    • 0027743449 scopus 로고
    • Spatial and temporal patterns of immunoreactive transforming growth factor β1, β2 and β3 during excisional wound repair
    • Levine J. H., Moses H. L., Gold L. I. and Nanney L. B. (1993) Spatial and temporal patterns of immunoreactive transforming growth factor β1, β2 and β3 during excisional wound repair. Am. J. Pathol. 143, 368-380.
    • (1993) Am. J. Pathol. , vol.143 , pp. 368-380
    • Levine, J.H.1    Moses, H.L.2    Gold, L.I.3    Nanney, L.B.4
  • 56
    • 0028230259 scopus 로고
    • Effects of transforming growth factor-β1 on scar production in the injured central nervous system of the rat
    • Logan A., Berry M., Gonzalez A. M., Frautschy S. A., Sporn M. B. and Baird M. W. J. (1994) Effects of transforming growth factor-β1 on scar production in the injured central nervous system of the rat. Eur. J. Neurosci. 6, 355-363.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 355-363
    • Logan, A.1    Berry, M.2    Gonzalez, A.M.3    Frautschy, S.A.4    Sporn, M.B.5    Baird, M.W.J.6
  • 57
    • 0028973641 scopus 로고
    • Elevated levels of platelet derived growth factor and transforming growth factor β1 in bronchoalveolar lavage fluid from patients with scleroderma
    • Ludwicka A., Ohba T., Trojanowska M., Yamakage A., Strange C., Smith E. A., Leroy E. C., Sutherland S. and Silver R. M. (1995) Elevated levels of platelet derived growth factor and transforming growth factor β1 in bronchoalveolar lavage fluid from patients with scleroderma. J. Rheum. 22, 1876-1883.
    • (1995) J. Rheum. , vol.22 , pp. 1876-1883
    • Ludwicka, A.1    Ohba, T.2    Trojanowska, M.3    Yamakage, A.4    Strange, C.5    Smith, E.A.6    Leroy, E.C.7    Sutherland, S.8    Silver, R.M.9
  • 58
    • 0028882261 scopus 로고
    • BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning
    • Luo G., Hofmann C., Bronckers A. L. J. J., Sohocki M., Bradley A. and Karsenty G. (1995) BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. Genes Dev. 9, 2808-2820.
    • (1995) Genes Dev. , vol.9 , pp. 2808-2820
    • Luo, G.1    Hofmann, C.2    Bronckers, A.L.J.J.3    Sohocki, M.4    Bradley, A.5    Karsenty, G.6
  • 59
    • 0025946857 scopus 로고
    • The DVR gene family in embryonic development
    • Lyons K. M., Jones C. M. and Hogan B. L. M. (1991) The DVR gene family in embryonic development. Trends Genet. 7, 408-412.
    • (1991) Trends Genet. , vol.7 , pp. 408-412
    • Lyons, K.M.1    Jones, C.M.2    Hogan, B.L.M.3
  • 60
    • 0025215307 scopus 로고
    • Mechanism of activation of latent recombinant transforming growth factor-β1 by plasmin
    • Lyons R. M., Gentry L. E., Purchio A. F. and Moses H. L. (1990) Mechanism of activation of latent recombinant transforming growth factor-β1 by plasmin. J. Cell Biol. 110, 1361-1367.
    • (1990) J. Cell Biol. , vol.110 , pp. 1361-1367
    • Lyons, R.M.1    Gentry, L.E.2    Purchio, A.F.3    Moses, H.L.4
  • 61
    • 0030031433 scopus 로고    scopus 로고
    • Localization of type-i procollagen gene expression in silica-induced granulomatous lung disease and implication of transforming growth factor β as a mediator of fibrosis
    • Mariani T. J., Roby J. D., Mecham R. P., Parks W. C., Crouch E. and Pierce R. A. (1996) Localization of type-I procollagen gene expression in silica-induced granulomatous lung disease and implication of transforming growth factor β as a mediator of fibrosis. Am. J. Pathol. 148, 151-164.
    • (1996) Am. J. Pathol. , vol.148 , pp. 151-164
    • Mariani, T.J.1    Roby, J.D.2    Mecham, R.P.3    Parks, W.C.4    Crouch, E.5    Pierce, R.A.6
  • 62
    • 0029417041 scopus 로고
    • TGF-β and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders
    • Martyre M. C. (1995) TGF-β and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders. Leukemia Lymphoma 20, 39.
    • (1995) Leukemia Lymphoma , vol.20 , pp. 39
    • Martyre, M.C.1
  • 63
    • 0025222517 scopus 로고
    • The transforming growth factor-beta family
    • Massagué J. (1990) The transforming growth factor-beta family. Annu. Rev. Cell. Biol. 6, 597-641.
    • (1990) Annu. Rev. Cell. Biol. , vol.6 , pp. 597-641
    • Massagué, J.1
  • 65
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signalling: Receptors, transducers and Mad proteins
    • Massagué J. (1996) TGFβ signalling: receptors, transducers and Mad proteins. Cell 85, 947-950.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 66
    • 0028279174 scopus 로고
    • Activin receptors and cellular signaling by the receptor serine kinase family
    • Mathews L. S. (1994) Activin receptors and cellular signaling by the receptor serine kinase family. Endocr. Rev. 15, 310-325.
    • (1994) Endocr. Rev. , vol.15 , pp. 310-325
    • Mathews, L.S.1
  • 69
    • 0028962723 scopus 로고
    • Pathogenesis of lung fibrosis and potential new therapeutic strategies
    • McAnulty R, J. and Laurent G. J. (1995) Pathogenesis of lung fibrosis and potential new therapeutic strategies. Exp. Nephrol. 3, 96-107.
    • (1995) Exp. Nephrol. , vol.3 , pp. 96-107
    • McAnulty, R.J.1    Laurent, G.J.2
  • 70
    • 0002358287 scopus 로고    scopus 로고
    • Fetal wound healing and the development of antiscarring therapies for adult wound healing
    • Ed. Clark R. A. F., Plenum Press, New York
    • McCallion R. L. and Ferguson M. W. J. (1996) Fetal wound healing and the development of antiscarring therapies for adult wound healing. In The Molecular and Cellular Biology of Wound Repair (Ed. Clark R. A. F.), pp. 561-600. Plenum Press, New York.
    • (1996) The Molecular and Cellular Biology of Wound Repair , pp. 561-600
    • McCallion, R.L.1    Ferguson, M.W.J.2
  • 73
    • 0025765844 scopus 로고
    • A role of the latent TGF-β1 binding protein in the assembly and secretion of TGFβ1
    • Miyazono K., Olofsson A., Colosetti P. and Heldin C. H. (1991) A role of the latent TGF-β1 binding protein in the assembly and secretion of TGFβ1. EMBO J. 10, 1091-1101.
    • (1991) EMBO J. , vol.10 , pp. 1091-1101
    • Miyazono, K.1    Olofsson, A.2    Colosetti, P.3    Heldin, C.H.4
  • 74
    • 0023262932 scopus 로고
    • Accelerated healing of incisional wounds in rats induced by transforming growth factor-β
    • Mustoe T. A., Pierce G. F., Thomason A., Gramates P., Sporn M. B. and Deuel T. F. (1987) Accelerated healing of incisional wounds in rats induced by transforming growth factor-β. Science 237, 1333-1336.
    • (1987) Science , vol.237 , pp. 1333-1336
    • Mustoe, T.A.1    Pierce, G.F.2    Thomason, A.3    Gramates, P.4    Sporn, M.B.5    Deuel, T.F.6
  • 75
    • 0025827178 scopus 로고
    • Immunohistochemical detection of transforming growth factor β1 in fibrotic liver diseases
    • Nagy P., Schaff Z. and Lapis K. (1991) Immunohistochemical detection of transforming growth factor β1 in fibrotic liver diseases. Hepalology 14, 269-273.
    • (1991) Hepalology , vol.14 , pp. 269-273
    • Nagy, P.1    Schaff, Z.2    Lapis, K.3
  • 76
    • 0028219896 scopus 로고
    • The expression of transforming growth factor type beta in fetal and adult rabbit skin wounds
    • Nath R. K., LaRegina M., Markham H., Ksander G. A. and Weeks P. M. (1994) The expression of transforming growth factor type beta in fetal and adult rabbit skin wounds. J. Pediat. Surg. 29, 416-421.
    • (1994) J. Pediat. Surg. , vol.29 , pp. 416-421
    • Nath, R.K.1    LaRegina, M.2    Markham, H.3    Ksander, G.A.4    Weeks, P.M.5
  • 77
    • 0026450848 scopus 로고
    • Expression of transforming growth factor β1 is increased in human vascular restenosis lesions
    • Nikol S., Isner J. M., Pickering J. G., Kearney M., Leclerc G. and Weir L. (1992) Expression of transforming growth factor β1 is increased in human vascular restenosis lesions. J. Clin. Invest. 90, 1582-1592.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1582-1592
    • Nikol, S.1    Isner, J.M.2    Pickering, J.G.3    Kearney, M.4    Leclerc, G.5    Weir, L.6
  • 78
    • 0025887628 scopus 로고
    • Purification of a new type high molecular weight receptor (Type V Receptor) of transforming growth factor β (TGF-β) from bovine liver
    • O'Grady P., Kuo M.-D., Baldassare J. J., Huang S. S. and Huang J. S. (1991) Purification of a new type high molecular weight receptor (Type V Receptor) of transforming growth factor β (TGF-β) from bovine liver. J. biol. Chem. 266, 8583-8589.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8583-8589
    • O'Grady, P.1    Kuo, M.-D.2    Baldassare, J.J.3    Huang, S.S.4    Huang, J.S.5
  • 79
    • 0026795503 scopus 로고
    • Purification and characterisation of transforming growth factor-β2.3 and -β1.2 heterodimers from bovine bone
    • Ogawa Y., Schmidt D. K., Dasch J. R., Chang R.-J. and Glaser C. B. (1992) Purification and characterisation of transforming growth factor-β2.3 and -β1.2 heterodimers from bovine bone. J. biol. Chem. 267, 2325-2328.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2325-2328
    • Ogawa, Y.1    Schmidt, D.K.2    Dasch, J.R.3    Chang, R.-J.4    Glaser, C.B.5
  • 80
    • 0025102712 scopus 로고
    • Elevated expression of transforming growth factor-β and proteoglycan production in experimental glomerulonephritis: Possible role in expansion of the mesangial extracellular matrix
    • Okuda S., Languino L. R., Rouslahti E. and Border W. A. (1990) Elevated expression of transforming growth factor-β and proteoglycan production in experimental glomerulonephritis: possible role in expansion of the mesangial extracellular matrix. J. Clin. Invest. 86, 453-462.
    • (1990) J. Clin. Invest. , vol.86 , pp. 453-462
    • Okuda, S.1    Languino, L.R.2    Rouslahti, E.3    Border, W.A.4
  • 81
    • 0025776771 scopus 로고
    • Activation of collagen gene expression in keloids: Co-localization of type I and type VI collagen and transforming growth factor β1 mRNA
    • Peltonen J., Hsiao L. L., Jaakkola S., Sollberg S., Aumailley M., Timpl R., Chu M. L. and Uitto J. (1991) Activation of collagen gene expression in keloids: co-localization of type I and type VI collagen and transforming growth factor β1 mRNA. J. Invest. Dermatol. 97, 240-248.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 240-248
    • Peltonen, J.1    Hsiao, L.L.2    Jaakkola, S.3    Sollberg, S.4    Aumailley, M.5    Timpl, R.6    Chu, M.L.7    Uitto, J.8
  • 82
    • 0000988121 scopus 로고
    • Transforming growth factor β reverses the glucocorticoid-induced wound healing deficit in rats: Possible regulation in macrophages by platelet-derived growth factor
    • Pierce G. F., Mustoe T. A., Lingelbach J., Masakowski V. R., Gramates P. and Deuel T. F. (1989) Transforming growth factor β reverses the glucocorticoid-induced wound healing deficit in rats: possible regulation in macrophages by platelet-derived growth factor. Proc. Natl Acad. Sci. U.S.A. 86, 2229-2233.
    • (1989) Proc. Natl Acad. Sci. U.S.A. , vol.86 , pp. 2229-2233
    • Pierce, G.F.1    Mustoe, T.A.2    Lingelbach, J.3    Masakowski, V.R.4    Gramates, P.5    Deuel, T.F.6
  • 84
    • 0023710423 scopus 로고
    • Identification of mannose 6-phosphate in 2 asparagine-linked sugar chains of recombinant transforming growth factor-β-1 precursor
    • Purchio A. F., Cooper J. A., Brunner A. M., Lioubin M. N., Gentry L. E., Kovacina K. S., Roth R. A. and Marquardt H. (1988) Identification of mannose 6-phosphate in 2 asparagine-linked sugar chains of recombinant transforming growth factor-β-1 precursor. J. biol. Chem. 263, 14211-14215.
    • (1988) J. Biol. Chem. , vol.263 , pp. 14211-14215
    • Purchio, A.F.1    Cooper, J.A.2    Brunner, A.M.3    Lioubin, M.N.4    Gentry, L.E.5    Kovacina, K.S.6    Roth, R.A.7    Marquardt, H.8
  • 85
    • 0025727212 scopus 로고
    • Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: Incisional wound model
    • Quaglino D., Nanney L. B., Ditesheim J. A. and Davidson J. M. (1991) Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model. J. Invest. Dermatol. 97, 34-42.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 34-42
    • Quaglino, D.1    Nanney, L.B.2    Ditesheim, J.A.3    Davidson, J.M.4
  • 86
    • 0024998055 scopus 로고
    • Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: Excisional wound model
    • Quaglino D., Nanney L. B., Kennedy R. and Davidson J. M. (1990) Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: excisional wound model. Lab. Invest. 63, 307-319.
    • (1990) Lab. Invest. , vol.63 , pp. 307-319
    • Quaglino, D.1    Nanney, L.B.2    Kennedy, R.3    Davidson, J.M.4
  • 87
    • 84989096027 scopus 로고    scopus 로고
    • Transforming growth factor β: Activity and efficacy in animal models of wound healing
    • Roberts A. B. (1996) Transforming growth factor β: activity and efficacy in animal models of wound healing. Wound Rep. Reg. 3, 408-418.
    • (1996) Wound Rep. Reg. , Issue.3 , pp. 408-418
    • Roberts A, B.1
  • 92
    • 0028351248 scopus 로고
    • Elevated expression of type-VII collagen in the skin of patients with systemic-sclerosis - Regulation by transforming growth-factor-β
    • Rudnicka L., Varga J., Christiane A. M., Iozzo R. V., Jimenez S. A. and Uitto J. (1994) Elevated expression of type-VII collagen in the skin of patients with systemic-sclerosis - regulation by transforming growth-factor-β. J. Clin. Invest. 93, 1709-1715.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1709-1715
    • Rudnicka, L.1    Varga, J.2    Christiane, A.M.3    Iozzo, R.V.4    Jimenez, S.A.5    Uitto, J.6
  • 94
    • 0030058699 scopus 로고    scopus 로고
    • Association of the small latent transforming growth factor-β with an eight cysteine repeat of its binding protein (LTBP-1)
    • Saharinen J., Taipale J. and Keski-Oja J. (1996) Association of the small latent transforming growth factor-β with an eight cysteine repeat of its binding protein (LTBP-1). EMBO J. 15, 245-253.
    • (1996) EMBO J. , vol.15 , pp. 245-253
    • Saharinen, J.1    Taipale, J.2    Keski-Oja, J.3
  • 95
    • 0025079739 scopus 로고
    • Gene expression in normal and doxorubicin-impaired wounds: Importance of transforming growth factor beta
    • Salomon G. D., Kasid A., Bernstein E., Buresh C., Director E. and Norton J. A. (1990) Gene expression in normal and doxorubicin-impaired wounds: importance of transforming growth factor beta. Surgery 108, 318-322.
    • (1990) Surgery , vol.108 , pp. 318-322
    • Salomon, G.D.1    Kasid, A.2    Bernstein, E.3    Buresh, C.4    Director, E.5    Norton, J.A.6
  • 97
    • 0029980518 scopus 로고    scopus 로고
    • Modulation of transforming growth factor β levels on microvascular endothelial cells during in vitro angiogenesis
    • Sankar S., Mahooti-Brooks N., Bensen L., McCarthy T. L., Centrella M. and Madri J. A. (1996) Modulation of transforming growth factor β levels on microvascular endothelial cells during in vitro angiogenesis. J. Clin. Invest. 97, 1436-1446.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1436-1446
    • Sankar, S.1    Mahooti-Brooks, N.2    Bensen, L.3    McCarthy, T.L.4    Centrella, M.5    Madri, J.A.6
  • 98
    • 0029337807 scopus 로고
    • Increased expression of transforming growth factor β isoforms (β1, β2, β3) in bleomycin-induced pulmonary fibrosis
    • Santana A., Saxena B., Noble N. A., Gold L. I. and Marshall B. C. (1995) Increased expression of transforming growth factor β isoforms (β1, β2, β3) in bleomycin-induced pulmonary fibrosis. Am. J. Resp. Cell. Mol. Biol. 13, 34-44.
    • (1995) Am. J. Resp. Cell. Mol. Biol. , vol.13 , pp. 34-44
    • Santana, A.1    Saxena, B.2    Noble, N.A.3    Gold, L.I.4    Marshall, B.C.5
  • 99
    • 0030058914 scopus 로고    scopus 로고
    • The C elegam sma-2, sma-3 and sma-4 genes define a novel conserved family of TGF-β pathway components
    • Savage C., Das P., Finelli A., Townsend S., Sun C., Baird S. and Padgett R. (1996) The C elegam sma-2, sma-3 and sma-4 genes define a novel conserved family of TGF-β pathway components. Proc. Natl Acad. Sci. U.S.A. 93, 790-794.
    • (1996) Proc. Natl Acad. Sci. U.S.A. , vol.93 , pp. 790-794
    • Savage, C.1    Das, P.2    Finelli, A.3    Townsend, S.4    Sun, C.5    Baird, S.6    Padgett, R.7
  • 100
    • 0027333290 scopus 로고
    • TGF-βs and TGF-β type II receptor in human epidermis: Differential expression in acute and chronic skin wounds
    • Schmid P., Cox D., Bilbe G., McMaster G., Morrison C., Stahelin H., Luscher N. and Seiler W. (1993a) TGF-βs and TGF-β Type II receptor in human epidermis: differential expression in acute and chronic skin wounds. J. Pathol. 171, 191-197.
    • (1993) J. Pathol. , vol.171 , pp. 191-197
    • Schmid, P.1    Cox, D.2    Bilbe, G.3    McMaster, G.4    Morrison, C.5    Stahelin, H.6    Luscher, N.7    Seiler, W.8
  • 101
    • 0027170515 scopus 로고
    • Injury induced expression of TGF-β1 mRNA is enhanced by exogenously applied TGF-βs
    • Schmid P., Kunz S., Cerletti N., McMaster G. and Cox D. (1993b) Injury induced expression of TGF-β1 mRNA is enhanced by exogenously applied TGF-βs. Biochem. Biophys. Res. Commun. 194, 399-406.
    • (1993) Biochem. Biophys. Res. Commun. , vol.194 , pp. 399-406
    • Schmid, P.1    Kunz, S.2    Cerletti, N.3    McMaster, G.4    Cox, D.5
  • 102
    • 0027305971 scopus 로고
    • Thrombospondin causes activation of latent transforming growth factor β secreted by endothelial cells by a novel mechanism
    • Schultz-Cherry S. and Murphy-Ulrich J. E. (1993) Thrombospondin causes activation of latent transforming growth factor β secreted by endothelial cells by a novel mechanism. J. Cell. Biol. 122, 923-932.
    • (1993) J. Cell. Biol. , vol.122 , pp. 923-932
    • Schultz-Cherry, S.1    Murphy-Ulrich, J.E.2
  • 103
    • 0028940853 scopus 로고
    • Genetic characterisation and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
    • Sekelsky J. J., Newfeld S. J., Raftery L. A., Chartoff E. H. and Gelbart W. M. (1995) Genetic characterisation and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.
    • (1995) Genetics , vol.139 , pp. 1347-1358
    • Sekelsky, J.J.1    Newfeld, S.J.2    Raftery, L.A.3    Chartoff, E.H.4    Gelbart, W.M.5
  • 104
    • 0026505458 scopus 로고
    • Control of scarring in adult wounds by neutralising antibody to transforming growth factor β
    • Shah M., Foreman D. M. and Ferguson M. W. J. (1992) Control of scarring in adult wounds by neutralising antibody to transforming growth factor β. Lancet 339, 213-214.
    • (1992) Lancet , vol.339 , pp. 213-214
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.J.3
  • 105
    • 0028174630 scopus 로고
    • Neutralizing antibodies to TGFβ1,2 reduces cutaneous scarring in adult rodents
    • Shah M., Foreman D. M. and Ferguson M. W. J. (1994) Neutralizing antibodies to TGFβ1,2 reduces cutaneous scarring in adult rodents. J. Cell Sci. 107, 1137-1157.
    • (1994) J. Cell Sci. , vol.107 , pp. 1137-1157
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.J.3
  • 106
    • 0028986030 scopus 로고
    • Neutralization of TGFβ1 and TGFβ2 or exogenous addition of TGFβ3 to cutaneous wounds reduces scarring
    • Shah M., Foreman D. M. and Ferguson M. W. J. (1995) Neutralization of TGFβ1 and TGFβ2 or exogenous addition of TGFβ3 to cutaneous wounds reduces scarring. J. Cell Sci. 108, 983-1002.
    • (1995) J. Cell Sci. , vol.108 , pp. 983-1002
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.J.3
  • 107
    • 0011288450 scopus 로고    scopus 로고
    • Fetal wound healing and scarless surgery
    • Eds Jackson I. T. and Sommerlad B. C., Churchill Livingstone, Edinburgh
    • Shah M., Whitby D. J. and Ferguson M. W. J. (1996) Fetal wound healing and scarless surgery. In Recent Advances in Plastic Surgery (Eds Jackson I. T. and Sommerlad B. C.), pp. 1-12. Churchill Livingstone, Edinburgh.
    • (1996) Recent Advances in Plastic Surgery , pp. 1-12
    • Shah, M.1    Whitby, D.J.2    Ferguson, M.W.J.3
  • 111
    • 37049184914 scopus 로고
    • Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo
    • Sporn M. B., Roberts A. B., Shull J. H., Smith J. M. and Ward J. M. (1983) Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science 219, 1329-1330.
    • (1983) Science , vol.219 , pp. 1329-1330
    • Sporn, M.B.1    Roberts, A.B.2    Shull, J.H.3    Smith, J.M.4    Ward, J.M.5
  • 112
    • 0026445528 scopus 로고
    • Transforming growth factor-beta: Recent progress and new challenges
    • Sporn M. B. and Roberts A. B. (1992) Transforming growth factor-beta: recent progress and new challenges. J. Cell. Biol. 119, 1017-1021.
    • (1992) J. Cell. Biol. , vol.119 , pp. 1017-1021
    • Sporn, M.B.1    Roberts, A.B.2
  • 113
    • 0011374950 scopus 로고    scopus 로고
    • Neutralizing antibody to TGF-β and mannose-6-phosphate modulate corneal wound healing following PRK
    • Sutton G. L., Patmore A., Verma S., Joussen A. M. and Marshall J. (1996) Neutralizing antibody to TGF-β and mannose-6-phosphate modulate corneal wound healing following PRK. Invest. Ophthal. Visual. Sci. 37, 924.
    • (1996) Invest. Ophthal. Visual. Sci. , vol.37 , pp. 924
    • Sutton, G.L.1    Patmore, A.2    Verma, S.3    Joussen, A.M.4    Marshall, J.5
  • 114
    • 0027976521 scopus 로고
    • Latent transforming growth factor β1 associates to fibroblast extracellular matrix via latent TGF-β binding protein
    • Taipale J., Miyazono K., Heldin C.-H. and Keski-Oja J. (1994) Latent transforming growth factor β1 associates to fibroblast extracellular matrix via latent TGF-β binding protein. J. Cell. Biol. 124, 171-181.
    • (1994) J. Cell. Biol. , vol.124 , pp. 171-181
    • Taipale, J.1    Miyazono, K.2    Heldin, C.-H.3    Keski-Oja, J.4
  • 116
    • 0029916476 scopus 로고    scopus 로고
    • Elevated levels of plasminogen-activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts
    • Tuan T. L., Zhu J. Y., Sun B., Nichter L. S., Nimni M. E. and Laug W. E. (1996) Elevated levels of plasminogen-activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts. J. Invest. Dermatol. 106, 1007-1011.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 1007-1011
    • Tuan, T.L.1    Zhu, J.Y.2    Sun, B.3    Nichter, L.S.4    Nimni, M.E.5    Laug, W.E.6
  • 118
    • 0023886444 scopus 로고
    • Latent transforming growth factor-β from human-platelets - A high molecular-weight complex containing precursor sequences
    • Wakefield L. M., Smith D. M., Flanders K. C. and Sporn M. B. (1988) Latent transforming growth factor-β from human-platelets - a high molecular-weight complex containing precursor sequences. J. biol. Chem. 263, 7646-7654.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7646-7654
    • Wakefield, L.M.1    Smith, D.M.2    Flanders, K.C.3    Sporn, M.B.4
  • 119
    • 0027999325 scopus 로고
    • Transforming growth factor β isoform 2-specific high affinity binding to native α2-macroglobulin
    • Webb D. J., Atkins T. L., Crookston K. P., Burmester J. K., Qian S. W. and Gonias S. L. (1994) Transforming growth factor β isoform 2-specific high affinity binding to native α2-macroglobulin. J. biol. Chem. 269, 30402-30406.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30402-30406
    • Webb, D.J.1    Atkins, T.L.2    Crookston, K.P.3    Burmester, J.K.4    Qian, S.W.5    Gonias, S.L.6
  • 120
    • 0027291380 scopus 로고
    • Altered expression of small proteoglycans, collagen, and transforming growth factor-β1 in developing bleomycin-induced pulmonary fibrosis in rats
    • Westergren-Thorsson G., Hernnas J., Sarnstrand B., Oldberg A., Heinegard D. and Malmstrom A. (1993) Altered expression of small proteoglycans, collagen, and transforming growth factor-β1 in developing bleomycin-induced pulmonary fibrosis in rats. J. Clin. Invest. 92, 632-637.
    • (1993) J. Clin. Invest. , vol.92 , pp. 632-637
    • Westergren-Thorsson, G.1    Hernnas, J.2    Sarnstrand, B.3    Oldberg, A.4    Heinegard, D.5    Malmstrom, A.6
  • 121
    • 0025847137 scopus 로고
    • The extracellular matrix in fetal and adult wound healing
    • Whitby D. J. and Ferguson M. W. J. (1991a) The extracellular matrix in fetal and adult wound healing. Development 112, 651-668.
    • (1991) Development , vol.112 , pp. 651-668
    • Whitby, D.J.1    Ferguson, M.W.J.2
  • 122
    • 0025946070 scopus 로고
    • Immunohistochemical localisation of growth factors in lip wounds of fetal, neonatal and adult mice
    • Whitby D. J. and Ferguson M. W. J. (1991b) Immunohistochemical localisation of growth factors in lip wounds of fetal, neonatal and adult mice. Dev. Biol. 147, 207-215.
    • (1991) Dev. Biol. , vol.147 , pp. 207-215
    • Whitby, D.J.1    Ferguson, M.W.J.2
  • 123
    • 0029022221 scopus 로고
    • GS domain mutations that constitutively activate TbRI, the downstream signalling component in the TGFβ receptor complex
    • Wieser R., Wrana J. L. and Massagué J. (1995) GS domain mutations that constitutively activate TbRI, the downstream signalling component in the TGFβ receptor complex. EMBO J. 14, 2199-2208.
    • (1995) EMBO J. , vol.14 , pp. 2199-2208
    • Wieser, R.1    Wrana, J.L.2    Massagué, J.3
  • 124
    • 0029997368 scopus 로고    scopus 로고
    • Hepatic silicosis, cirrhosis, and liver-tumors in mice and hamsters - Studies of transforming growth-factor-β expression
    • Williams A. O. and Knapton A. D. (1996) Hepatic silicosis, cirrhosis, and liver-tumors in mice and hamsters - studies of transforming growth-factor-β expression. Hepatology 23, 1268-1275.
    • (1996) Hepatology , vol.23 , pp. 1268-1275
    • Williams, A.O.1    Knapton, A.D.2
  • 125
    • 0026721147 scopus 로고
    • The bone morphogenetic protein family and osteogenesis
    • Wozney J. M. (1992) The bone morphogenetic protein family and osteogenesis. Mol. Reprod. Dev. 32, 160-167.
    • (1992) Mol. Reprod. Dev. , vol.32 , pp. 160-167
    • Wozney, J.M.1
  • 128
    • 0027479442 scopus 로고
    • Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy
    • Yamamoto T., Nakamura T., Noble N. A., Rouslahti E. and Border W. A. (1993) Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy. Proc. Natl Acad. Sci. U.S.A. 90, 1814-1818.
    • (1993) Proc. Natl Acad. Sci. U.S.A. , vol.90 , pp. 1814-1818
    • Yamamoto, T.1    Nakamura, T.2    Noble, N.A.3    Rouslahti, E.4    Border, W.A.5
  • 129
    • 0028280073 scopus 로고
    • Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis
    • Yamamoto T., Noble N. A., Miller D. E. and Border W. A. (1994) Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis. Kidney Int. 45, 916-927.
    • (1994) Kidney Int. , vol.45 , pp. 916-927
    • Yamamoto, T.1    Noble, N.A.2    Miller, D.E.3    Border, W.A.4
  • 131
    • 0028218461 scopus 로고
    • Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor β
    • Ziyadeh F. N., Sharma K., Ericksen M. and Wolf G. (1994) Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor β. J. Clin. Invest. 93, 536-542.
    • (1994) J. Clin. Invest. , vol.93 , pp. 536-542
    • Ziyadeh, F.N.1    Sharma, K.2    Ericksen, M.3    Wolf, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.