Hypertension and hypothalamo-pituitary-adrenal axis hyperactivity affect frontal lobe integrity

Journal of Clinical Endocrinology and Metabolism

Volumn 90, Issue 6, 2005, Pages 3262-3267

  Gold, Stefan M ^a   Dziobek, Isabel ^a   Rogers, Kimberley ^a   Bayoumy, Abdul ^a   McHugh, Pauline F ^a   Convit, Antonio ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; GLUCOCORTICOID; CORTICOTROPIN; HYDROCORTISONE;

ADULT; AGED; ARTICLE; BODY MASS; BRAIN ATROPHY; BRAIN REGION; BRAIN SIZE; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEEDBACK SYSTEM; FEMALE; FRONTAL LOBE; FUNCTIONAL ASSESSMENT; HUMAN; HYPERTENSION; HYPOPHYSIS ADRENAL SYSTEM; LABORATORY TEST; MALE; MEASUREMENT; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT; PRIORITY JOURNAL; SCORING SYSTEM; STATISTICAL ANALYSIS; TEMPORAL LOBE; VOLUMETRY; AREA UNDER THE CURVE; BLOOD; BLOOD PRESSURE; HISTOLOGY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INTELLIGENCE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; REFERENCE VALUE; URINE;

ADRENOCORTICOTROPIC HORMONE; AGED; AREA UNDER CURVE; BLOOD PRESSURE; BODY MASS INDEX; FEMALE; FRONTAL LOBE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; HYPERTENSION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INTELLIGENCE; MALE; MIDDLE AGED; PITUITARY-ADRENAL SYSTEM; REFERENCE VALUES;

EID: 21244456908     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-2181     Document Type: Article

References (51)

1. Whitworth JA, Mangos GJ, Kelly JJ 2000 Cushing, cortisol, and cardiovascular disease. Hypertension 36:912-916
2. Kino T, Vottero A, Charmandari E, Chrousos GP 2002 Familial/sporadic glucocorticoid resistance syndrome and hypertension. Ann NY Acad Sci 970:101-111
3. Torpy DJ, Mullen N, Ilias I, Nieman LK 2002 Association of hypertension and hypokalemia with Cushing's syndrome caused by ectopic ACTH secretion: a series of 58 cases. Ann NY Acad Sci 970:134-144
4. Fernandez-Real JM, Engel WR, Simo R, Salinas I, Webb SM 1998 Study of glucose tolerance in consecutive patients harbouring incidental adrenal tumours. Study Group of Incidental Adrenal Adenoma. Clin Endocrinol (Oxf) 49:53-61
5. Rossi R, Tauchmanova L, Luciano A Di Martino M, Battista C, Del Viscovo L, Nuzzo V, Lombardi G 2000 Subclinical Cushing's syndrome in patients with adrenal incidentaloma: clinical and biochemical features. J Clin Endocrinol Metab 85:1440-1448
6. Vermeulen A, Van der Straeten M 1963 Adrenal cortical function in benign essential hypertension. J Clin Endocrinol Metab 23:574-578
7. Reynolds RM, Walker BR, Syddall HE, Whorwood CB, Wood PJ, Phillips DI 2001 Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors. J Clin Endocrinol Metab 86:245-250
8. Lupien SJ, Nair NP, Briere S, Maheu F, Tu MT, Lemay M, McEwen BS, Meaney MJ 1999 Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev Neurosci 10:117-139
9. Starkman M, Gebarski S, Berent S, Schteingart D 1992 Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome. Biol Psychiatry 32:756-765
10. Bourdeau I, Bard C, Noel B, Leclerc I, Cordeau MP, Belair M, Lesage J, Lafontaine L, Lacroix A 2002 Loss of brain volume in endogenous Cushing's syndrome and its reversibility after corection of hypercortisolism. J Clin Endocrinol Metab 87:1949-1954
11. Starkman MN, Giordani B, Berent S, Schork MA, Schteingart DE 2001 Elevated cortisol levels in Cushing's disease are associated with cognitive decrements. Psychosom Med 63:985-993
12. Starkman MN, Giordani B, Gebarski SS, Schteingart DE 2003 Improvement in learning associated with increased hippocampal formation volume. Biol Psychiatry 53:233-238
13. Kivipelto M, Soininen H, Tuomilehto J 2002 Hypertension and white matter lesions of the brain. J Hypertension 20:387-389
14. Goldstein IB, Bartzokis G, Guthrie D, Shapiro D 2002 Ambulatory blood pressure and brain atrophy in the healthy elderly. Neurology 59:713-719
15. Taki Y, Goto R, Evans A Zijdenbos A, Neelin P, Lerch J, Sato K, Ono S, Kinomura S, Nakagawa M, Sugiura M, Watanabe J, Kawashima R, Fukuda H 2004 Voxel-based morphometry of human brain with age and cerebrovascular risk factors. Neurobiol Aging 25:455-463
16. Den Heijer T, Skoog I, Oudkerk M, de Leeuw FE, de Groot JC, Hofman A, Breteler MM 2003 Association between blood pressure levels over time and brain atrophy in the elderly. Neurobiol Aging 24:307-313
17. DeCarli C, Miller BL, Swan GE, Reed T, Wolf PA, Garner J, Jack L, Carmelli D 1999 Predictors of brain morphology for the men of the NHLBI twin study. Stroke 30:529-536
18. Waldstein SR, Manuck SB, Ryan CM, Muldoon MF 1991 Neuropsychological correlates of hypertension: review and methodologic considerations. Psychol Bull 110:451-468
19. Raz N, Rodrigue KM, Acker JD 2003 Hypertension and the brain: vulnerability of the prefrontal regions and executive functions. Behav Neurosci 117:1169-1180
20. Reisberg B, Ferris SH, de Leon MJ, Crook T 1982 The global deterioration scale for assessment of primary degenerative dementia. Am J Psychiatry 139:1136-1139
21. Reisberg B, Ferris SH, de Leon MJ, Crook T 1988 The Global Deterioration Scale (GDS). Psychopharmacol Bull 24:661-663
22. McEwen BS 2003 Mood disorders and allostatic load. Biol Psychiatry 54:200-207
23. Hamilton M 1967 Development of a rating scale for primary depression illness. Br J Soc Clin Psychol 6:278-296
24. Expert Panel 2001 Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP). Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc 285:2486-2497
25. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL, Jones DW, Materson BJ, Oparil S, Wright Jr JT, Roccella EJ 2003 Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42:1206-1252
26. Heuser I, Yassouridis A, Holsboer F 1994 The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J Psychiat Res 28:341-356
27. Seeman TE, McEwen BS, Singer BH, Albert MS, Rowe JW 1997 Increase in urinary cortisol excretion and memory declines: macarthur studies of successful aging. J Clin Endocrinol Metab 82:2458-2465
28. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA 1987 MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. Am J Roentgenol 149:351-356
29. Convit A, de Leon MJ, Tarshish C, De Santi S, Tsui W, Rusinek H, George A 1997 Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol Aging 18:131-138
30. Convit A, Wolf OT, de Leon MJ Patalinjug M, Kandil E, Caraos C, Scherer A, Saint Louis LA, Cancro R 2001 Volumetric analysis of the pre-frontal regions: findings in aging and schizophrenia. Psychiatry Res 107:61-73
31. Jack CRJ, Bentley MD, Twomey CK, Zinsmeister AR 1990 MR Imaging-based volume measurements of the hippocampal formation and anterior temporal lobe: validation studies. Radiology 176:205-209
32. Haller J, Botteron K, Brunsden B 1994 Hippocampal MR volumetry. Proc SPIE Int Soc Opt Eng 2359:660-671
33. Convit A, McHugh PF, Wolf OT, de Leon MJ, Bobinski M, De Santi S, Roche A, Tsui W 1999 MRI volume of the amygdala: A reliable method allowing separation from the hippocampal formation. Psychiatry Res 90:113-123
34. Van Petten C 2004 Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. Neuropsychologia 42:1394-1413
35. Zachary RA 1940 Shipley Institute of Living Scale-revised. Los Angeles: Western Psychological Services
36. Cockrell JR, Folstein MF 1988 Mini-mental state examination (MMSE). Psychopharmacol Bull 24:689-692
37. Wechsler D 1955 Wechsler adult intelligence scale. New York: Psychological Corp
38. Moran LJ, Mefferd RB 1959 Repetitive psychometric measures. Psychol Rep 5:269-275
39. Wechsler D 1987 Wechsler memory scale-revised. San Antonio: Psychological Corp/Harcourt Brace Javanovich
40. Stroop JR 1935 Studies of interference in serial verbal reactions. J Exp Psychol 18:643-662
41. Shallice T 1982 Specific impairment of planning. Philos Trans R Soc Lond B 298:199-209
42. Moore TL, Killiany RJ, Rosene DL, Prusty S, Hollander W, Moss MB 2002 Impairment of executive function induced by hypertension in the rhesus monkey (Macaca mulatta). Behav Neurosci 116:387-396
43. Wiseman RM, Saxby BK, Burton EJ, Barber R, Ford GA, O'Brien JT 2004 Hippocampal atrophy, whole brain volume, and white matter lesions in older hypertensive subjects. Neurology 63:1892-1897
44. Sheline YI 2003 Neuroimaging studies of mood disorder effects on the brain. Biol Psychiatry 54:338-352
45. Sullivan RM, Gratton A 2002 Prefrontal cortical regulation of hypothalamic-pituitary-adrenal function in the rat and implications for psychopathology: side matters. Psychoneuroendocrinology 27:99-114
46. Tchiteya BM, Lecours AR, Elie R, Lupien SJ 2003 Impact of a unilateral brain lesion on cortisol secretion and emotional state: anterior/posterior dissociation in humans. Psychoneuroendocrinology 28:674-686
47. Sapolsky RM, Pulsinelli WA 1985 Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications. Science 229:1397-1400
48. Tsubota S, Adachi N, Chen J, Yorozuya T, Nagaro T, Arai T 1999 Dexamethasone changes brain monoamine metabolism and aggravates ischemic neuronal damage in rats. Anesthesiology 90:515-523
49. Sugo N, Hurn PD, Morahan MB, Hattori K, Traystman RJ, DeVries AC 2002 Social stress exacerbates focal cerebral ischemia in mice. Stroke 33:1660-1664
50. Tuor UI, Chumas PD, Del Bigio MR 1995 Prevention of hypoxic-ischemic damage with dexamethasone is dependent on age and not influenced by fasting. Exp Neurol 132:116-122
51. Walker BR, Best R, Shackleton CH, Padfield PL, Edwards CR 1996 Increased vasoconstrictor sensitivity to glucocorticoids in essential hypertension. Hypertension 27:190-196